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Validation and update of a prediction model for risk of relapse after cessation of anti-TNF treatment in Crohn’s disease2022 European Journal of Gastroenterology & Hepatology article Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Sebastiaan ten Bokkel Huinink, D C de Jong, Daan Nieboer, Doranne Thomassen, Ewout Willem Steyerberg, Marcel G. W. Dijkgraaf, +19 more
4citations -
Validation of biomarkers of aging2024 Nature Medicine article Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Mahdi Moqri, Chiara Maria Stella Herzog, Jesse R. Poganik, Kejun Ying, Jamie Nicole Justice, Daniel W. Belsky, +23 more
331citations -
Development and validation of the PORTRET tool to predict recurrence, overall survival, and other-cause mortality in older patients with breast cancer in the Netherlands: a population-based study2021 The Lancet Healthy Longevity article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access
Willeke G van der Plas-Krijgsman, Daniele Giardiello, Hein Putter, Ewout Willem Steyerberg, Esther Bastiaannet, Anne Margarethe Stiggelbout, +5 more
30citations -
Prospective validation of the BOADICEA multifactorial breast cancer risk prediction model in a large prospective cohort study2022 Journal of Medical Genetics article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Xin Yang, Mikael Eriksson, Kamila Czene, Andrew Lee, Goska Leslie, Michael J. Lush, +9 more
98citations -
Transfer Learning and Machine Learning for Training Five-Year Survival Prognostic Models in Early Breast Cancer: Development and Validation Study2026 Journal of Medical Internet Research article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access
Lisa Pilgram, Kai Yang, Ana-Alicia Beltran-Bless, Gregory R. Pond, Lisa Vandermeer, John Frederick Hilton, +17 more
0citations -
Transfer Learning and Machine Learning for Training Five-Year Survival Prognostic Models in Early Breast Cancer: Development and Validation Study2026 Journal of Medical Internet Research article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access
Lisa Pilgram, Kai Yang, Ana-Alicia Beltran-Bless, Gregory R. Pond, Lisa Vandermeer, John Frederick Hilton, +19 more
0citations -
Validation of the BOADICEA Model in a Prospective Cohort of BRCA1/2 Pathogenic Variant Carriers2024 medRxiv preprint Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Xin Yang, Thea M. Mooij, Goska Leslie, Lorenzo Ficorella, Nadine Andrieu, Karin Kast, +34 more
2citations -
External validation of PREDICT Breast v3.1 for overall survival in international cohorts, including young and invasive lobular subgroups2026 Breast Cancer Research and Treatment article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access
Elfi M. Verheul, Frank Doornkamp, Iurii Petrov, Sabine Siesling, Hester Floor Lingsma, Linetta B. Koppert, +32 more
0citations -
Computational Models for Clinical Applications in Personalized Medicine—Guidelines and Recommendations for Data Integration and Model Validation2022 Journal of Personalized Medicine article Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Catherine Bjerre Collin, Tom Gebhardt, Martin Golebiewski, Tugce Karaderi, Maximilian Hillemanns, Faiz M. Khan, +4 more
116citations -
Validation of the BOADICEA model and a 313-variant polygenic risk score for breast cancer risk prediction in a Dutch prospective cohort2020 Genetics in Medicine article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Inge M. M. Lakeman, Mar Rodríguez‐Girondo, Andrew Lee, Rikje Ruiter, Bruno H. Ch. Stricker, Sara Renata Alex Wijnant, +6 more
90citations -
Validation of the BOADICEA model in a prospective cohort of BRCA1/2 pathogenic variant carriers2024 Journal of Medical Genetics article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Xin Yang, Thea M. Mooij, Goska Leslie, Lorenzo Ficorella, Nadine Andrieu, Karin Kast, +34 more
16citations -
Validation of the Prognostic Performance of Breast Cancer Index in Hormone Receptor–Positive Postmenopausal Breast Cancer Patients in the TEAM Trial2024 Clinical Cancer Research article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access
John M.S. Bartlett, Keying Xu, Jenna Wong, Gregory R. Pond, Yi Zhang, Melanie Spears, +11 more
6citations -
Validation of tRNA-derived fragments as diagnostic biomarkers in suspected acute stroke; limitations in analysis and quantification methods2025 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology RNA modifications and cancer Open access
Tamar Woudenberg, M. Leontien van der Bent, Daphne A. L. van den Homberg, Thuy Nguyen, Marieke J.H. Wermer, Ido R. van den Wijngaard, +3 more
4citations -
Validation of minimal risk of recurrence classification by the Breast Cancer Index in early stage breast cancer2025 npj Breast Cancer article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access
Marie-France Jilderda, John M.S. Bartlett, Gerrit‐Jan Liefers, Y Zhang, Hywel Dunn-Davies, Valerie Rebattu, +12 more
2citations -
PREDICT version 3.1 overestimates survival in older women with breast cancer: a population-based external validation2026 The Breast article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access
Julia N. Wolbink, Leti van Bodegom‐Vos, Luuk C. A. Ciere, Saskia le Cessie, Hein Putter, Anna Z. de Boer, +4 more
0citations -
EchoGO validation bundle: frozen materials for cross-species consensus enrichment in transcriptomic interpretation2026 Zenodo (CERN European Organization for Nuclear Research) dataset Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Camilo Escobar-Sierra, Felix Langschied, Angelina Miller, Pedro A. Inostroza
0citations -
EchoGO validation and reproducibility compendium2026 Zenodo (CERN European Organization for Nuclear Research) dataset Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Camilo Escobar-Sierra, Felix Langschied, Angelina Miller, Pedro A. Inostroza
0citations -
EchoGO validation and reproducibility compendium2026 Zenodo (CERN European Organization for Nuclear Research) dataset Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Camilo Escobar-Sierra, Felix Langschied, Angelina Miller, Pedro A. Inostroza
0citations -
Advancing methanotroph bioprocessing with novel small-scale methane transfer measurement, scale-up validation, and gas composition optimization0citations
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P388 Prediction model to safely CEASE anti-TNF therapy in Crohn’s disease: validation of a predictive diagnostic tool for the cessation of anti-TNF treatment in CD in a Dutch population2020 Journal of Crohn s and Colitis conference-abstract Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Sebastiaan ten Bokkel Huinink, D. de Jong, Janneke van der Woude, Daan Nieboer, Ewout Willem Steyerberg, Frank H.J. Wolfhagen, +14 more
0citations -
Recommendations for detection, validation, and evaluation of RNA editing events in cardiovascular and neurological/neurodegenerative diseases2023 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology RNA regulation and disease Open access
Korina Karagianni, Alessia Bibi, Alisia Madè, Shubhra Acharya, Mikko Parkkonen, Teodora Barbălată, +7 more
21citations -
Validation of the 70-gene signature test (MammaPrint) to identify patients with breast cancer aged ≥ 70 years with ultralow risk of distant recurrence: A population-based cohort study2022 Journal of Geriatric Oncology article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access
Iris Noordhoek, Esther Bastiaannet, Nienke Aafke de Glas, Josien C C Scheepens, Laura J. Esserman, Jelle Wesseling, +7 more
15citations -
External validation and clinical utility assessment of PREDICT breast cancer prognostic model in young, systemic treatment-naïve women with node-negative breast cancer2023 European Journal of Cancer article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access
Yuwei Wang, Annegien Broeks, Daniele Giardiello, Michael Hauptmann, Katarzyna Jóźwiak, Esther A. Koop, +13 more
6citations -
Definition and Validation of an Exposure Measurement Method for a Typical Load of a Base Station2025 Bioelectromagnetics article Biochemistry, Genetics and Molecular Biology Electromagnetic Fields and Biological Effects Open access
Anna‐Malin Schiffarth, Tam Julian Ta, Christian Bornkessel, Lisa‐Marie Schilling, Matthias Hein, Dirk Heberling
2citations -
Validation of the association between MRI and gene signatures in facioscapulohumeral dystrophy muscle: implications for clinical trial design2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access
Chao-Jen Wong, Seth D. Friedman, Lauren D. Snider, Sean R. Bennett, Takako Iida Jones, Peter L. Jones, +10 more
2citations