September 25, 2026 article Open access Unlocking microbial dark matter: A biotechnology framework for replenishing the antibiotic pipeline Biotechnology Advances DOI: 10.1016/j.biotechadv.2026.109054 Full text (OA) OpenAlex Authors 0 Author list not loaded yet. Cited by 0 stored of 0 References 12 Search Sort Most cited Newest Oldest Patent citations Title Any typearticle review book-chapter conference-paper preprint dissertation book dataset other Any fieldAgricultural and Biological Sciences Arts and Humanities Biochemistry, Genetics and Molecular Biology Business, Management and Accounting Chemical Engineering Chemistry Computer Science Decision Sciences Dentistry Earth and Planetary Sciences Economics, Econometrics and Finance Energy Engineering Environmental Science Health Professions Immunology and Microbiology Materials Science Mathematics Medicine Neuroscience Nursing Pharmacology, Toxicology and Pharmaceutics Physics and Astronomy Psychology Social Sciences Veterinary Open access Natural products in drug discovery: advances and opportunities 2021 Nature Reviews Drug Discovery review Medicine Microbial Natural Products and Biosynthesis Open access cited by 8 patents 5,478 citations antiSMASH 6.0: improving cluster detection and comparison capabilities 2021 Nucleic Acids Research article Medicine Microbial Natural Products and Biosynthesis Open access cited by 7 patents 2,597 citations antiSMASH 7.0: new and improved predictions for detection, regulation, chemical structures and visualisation 2023 Nucleic Acids Research article Medicine Microbial Natural Products and Biosynthesis Open access cited by 2 patents 2,311 citations MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration 2024 Nucleic Acids Research article Medicine Microbial Natural Products and Biosynthesis Open access 252 citations A community resource for paired genomic and metabolomic data mining 2021 Nature Chemical Biology article Medicine Microbial Natural Products and Biosynthesis Open access cited by 1 patent 130 citations Maximizing Heterologous Expression of Engineered Type I Polyketide Synthases: Investigating Codon Optimization Strategies 2023 ACS Synthetic Biology article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access 43 citations PARAS: High-Accuracy Machine Learning of Substrate Specificities in Nonribosomal Peptide Synthetases 2026 JACS Au article Medicine Microbial Natural Products and Biosynthesis Open access 34 citations MITE: the Minimum Information about a Tailoring Enzyme database for capturing specialized metabolite biosynthesis 2025 Nucleic Acids Research article Medicine Microbial Natural Products and Biosynthesis Open access 11 citations Discovery and Derivatization of Tridecaptin Antibiotics with Altered Host Specificity and Enhanced Bioactivity 2024 ACS Chemical Biology article Medicine Microbial Natural Products and Biosynthesis Open access 9 citations Translating community-wide spectral library into actionable chemical knowledge: a proof of concept with monoterpene indole alkaloids 2025 Journal of Cheminformatics article Chemistry Mass Spectrometry Techniques and Applications Open access 7 citations nanoRAPIDS as an analytical pipeline for the discovery of novel bioactive metabolites in complex culture extracts at the nanoscale 2024 Communications Chemistry article Medicine Microbial Natural Products and Biosynthesis Open access 5 citations FERMO: A Dashboard for Biochemometric Prioritization of Molecular Features from Mass Spectral Data 2026 ACS Measurement Science Au article Biochemistry, Genetics and Molecular Biology Metabolomics and Mass Spectrometry Studies Open access 2 citations 12 results