Developing downstream processes for the purification of recombinant proteins and small molecules from Nicotiana benthamiana biomass

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  2020 Biotechnology Advances article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications

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  2020 Biotechnology Advances article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access cited by 2 patents

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• The Emergency Response Capacity of Plant-Based Biopharmaceutical Manufacturing-What It Is and What It Could Be

  2020 Frontiers in Plant Science article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access

  78

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• The use of predictive models to develop chromatography-based purification processes

  2022 Frontiers in Bioengineering and Biotechnology article Biochemistry, Genetics and Molecular Biology Protein purification and stability Open access

  51

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• Simple plant‐based production and purification of the assembled human ferritin heavy chain as a nanocarrier for tumor‐targeted drug delivery and bioimaging in cancer therapy

  2022 Biotechnology and Bioengineering article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access

  30

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• A combined pH and temperature precipitation step facilitates the purification of tobacco‐derived recombinant proteins that are sensitive to extremes of either parameter

  2020 Biotechnology Journal article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access

  28

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• Killer to cure: Expression and production costs calculation of tobacco plant‐made cancer‐immune checkpoint inhibitors

  2023 Plant Biotechnology Journal article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access

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• Advanced score system and automated search strategies for parameter estimation in mechanistic chromatography modeling

  2021 Journal of Chromatography A article Chemistry Analytical Chemistry and Chromatography Open access cited by 2 patents

  24

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• Bayesian optimization using multiple directional objective functions allows the rapid inverse fitting of parameters for chromatography simulations

  2022 Journal of Chromatography A article Chemistry Analytical Chemistry and Chromatography Open access

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• Nicotiana spp. for the Expression and Purification of Functional IgG3 Antibodies Directed Against the Staphylococcus aureus Alpha Toxin

  2021 Frontiers in Chemical Engineering book-review Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access

  19

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• Design, optimization, production and activity testing of recombinant immunotoxins expressed in plants and plant cells for the treatment of monocytic leukemia

  2023 Bioengineered article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access

  14

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• Precision analysis for the determination of steric mass action parameters using eight tobacco host cell proteins

  2021 Journal of Chromatography A article Biochemistry, Genetics and Molecular Biology Protein purification and stability Open access

  13

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• Optimizing interleukin-6 and 8 expression, clarification and purification in plant cell packs and plants for application in advanced therapy medicinal products and cellular agriculture

  2024 Journal of Biotechnology article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access

  11

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• Membrane-based inverse-transition purification facilitates a rapid isolation of various spider-silk elastin-like polypeptide fusion proteins from extracts of transgenic tobacco

  2024 Transgenic Research article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access

  7

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• Extraction and purification of malaria vaccine candidate CLCT produced by transient expression in Nicotiana benthamiana plants

  2023 Discover Chemical Engineering article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access

  6

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15 results