Modulation of the ACOD1/itaconate pathway differentially affects atherosclerosis severity across genetic models and sexes

Journal of Clinical Investigation, vol. 135

Abstract

Haase, Lara; Belkacemi, Anouar; Neises, Laura; Kiweler, Nicole; Wesely, Christine; Huchzermeier, Rosanna; Bozic, Maja; Khakdan, Arefeh; Sánchez, Marta; Mary, Arnaud; Sachs, Nadja; Winter, Hanna; Glaab, Enrico; Heneka, Michael T.; van der Vorst, Emiel Pc; Mittelbronn, Michel; Meiser, Johannes; Schneider, Jochen G.

Authors 16

1. Lara Haase

   University of Luxembourg · Luxembourg Institute of Health · Luxembourg Centre for Systems Biomedicine

   Affiliation as printed

   Cancer Metabolism Group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg

   Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Campus Belval, Esch-sur-Alzette, Luxembourg

2. Anouar Belkacemi

   Heidelberg University · German Centre for Cardiovascular Research

   Affiliation as printed

   German Centre for Cardiovascular Research (DZHK), Heidelberg/Mannheim/Munich, Germany

   Institute of Pharmacology, Heidelberg University, Heidelberg, Germany

3. Laura Neises

   Luxembourg Institute of Health

   Affiliation as printed

   Cancer Metabolism Group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg

4. Nicole Kiweler

   Luxembourg Institute of Health

   Affiliation as printed

   Cancer Metabolism Group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg

5. Christine Wesely

   Saarland University

   Affiliation as printed

   Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany

6. Rosanna Huchzermeier Aachen Department of Internal Medicine I (Cardiology)

   Universitätsklinikum Aachen

   Affiliation as printed

   Department of Internal Medicine-I, University Hospital Aachen, Aachen, Germany

7. Arefeh Khakdan

   University of Luxembourg

   Affiliation as printed

   Department of Life Science and Medicine, University of Luxembourg, Campus Belval, Esch-sur-Alzette, Luxembourg

8. Arnaud Mary

   University of Luxembourg · Luxembourg Centre for Systems Biomedicine

   Affiliation as printed

   Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Campus Belval, Esch-sur-Alzette, Luxembourg

9. Nadja Sachs

   TUM Klinikum · German Centre for Cardiovascular Research · Technical University of Munich

   Affiliation as printed

   Department of Vascular Surgery, and

   German Centre for Cardiovascular Research (DZHK), Heidelberg/Mannheim/Munich, Germany

   Department for Vascular and Endovascular Surgery, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany

10. Hanna Winter

    TUM Klinikum · German Centre for Cardiovascular Research · Technical University of Munich

    Affiliation as printed

    German Centre for Cardiovascular Research (DZHK), Heidelberg/Mannheim/Munich, Germany

    Institute of Molecular Vascular Medicine, TUM University Hospital, Munich, Germany

    Department for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

11. Enrico Glaab

    University of Luxembourg · Luxembourg Centre for Systems Biomedicine

    Affiliation as printed

    Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Campus Belval, Esch-sur-Alzette, Luxembourg

12. Michael Thomas Heneka

    University of Luxembourg · Luxembourg Centre for Systems Biomedicine

    Affiliation as printed

    Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Campus Belval, Esch-sur-Alzette, Luxembourg

13. Emiel P. C. van der Vorst Aachen Department of Internal Medicine I (Cardiology)

    Universitätsklinikum Aachen · Ludwig-Maximilians-Universität München

    Affiliation as printed

    Department of Internal Medicine-I, University Hospital Aachen, Aachen, Germany

    Institute for Cardiovascular Prevention, Ludwig-Maximilians-Universität, Munich, Germany

14. Michel Guy André Mittelbronn

    University of Luxembourg

    Affiliation as printed

    Department of Life Science and Medicine, University of Luxembourg, Campus Belval, Esch-sur-Alzette, Luxembourg

15. Johannes Meiser

    Luxembourg Institute of Health

    Affiliation as printed

    Cancer Metabolism Group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg

16. Jochen G. Schneider corresponding

    University of Luxembourg · Luxembourg Centre for Systems Biomedicine

    Affiliation as printed

    Department of Life Science and Medicine, University of Luxembourg, Campus Belval, Esch-sur-Alzette, Luxembourg

    Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Campus Belval, Esch-sur-Alzette, Luxembourg