A

How does DeepSeek-R1 perform on USMLE?

medRxiv

Abstract

Abstract DeepSeek, a Chinese artificial intelligence company, released its first free chatbot app based on its DeepSeek-R1 model. DeepSeek provides its models, algorithms, and training details to ensure transparency and reproducibility. Their new model is trained with reinforcement learning, allowing it to learn through interactions and feedback rather than relying solely on supervised learning. Reports showcase that DeepSeek’s model shows competitive performances against established large language models (LLMs) such as Anthropic’s Claude and OpenAI’s GPT-4o on established benchmarks in language understanding, mathematics (AIME 2024) and programming (Codeforces) while trained at a fraction of the costs. Additionally, running inference shows significantly lower costs, leading to DeepSeek surpassing ChatGPT as the most downloaded free app on the American iOS App Store. This development contributed to a nearly 17% drop in Nvidia’s share price, resulting in the most significant one-day loss in U.S. history, amounting to nearly $600 billion. The open-source models also bring a significant shift in the healthcare system, allowing cost-efficient medical LLMs to be deployed within hospital networks. To understand its performance in the healthcare sector, we analyse the new DeepSeek-R1 model on the United States Medical Licensing Examination (USMLE) and compare it to ChatGPT.

Authors 4

  1. Essen University Hospital

    Affiliation as printed

    Institute for Artificial Intelligence in Medicine (IKIM), Essen University Hospital (AöR), Girardetstraße 2, 45131 Essen, Germany

  2. Essen University Hospital

    Affiliation as printed

    Center for Virtual and Extended Reality in Medicine (ZvRM), Essen University Hospital (AöR), Hufelandstraße 55, 45147 Essen, Germany

    Institute for Artificial Intelligence in Medicine (IKIM), Essen University Hospital (AöR), Girardetstraße 2, 45131 Essen, Germany

  3. Universitätsklinikum Aachen · RWTH Aachen University

    Affiliation as printed

    Department of Oral and Maxillofacial Surgery, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074 Aachen, Germany

    Institute of Medical Informatics, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074 Aachen, Germany

  4. Jan Egger corresponding

    Essen University Hospital · Stiftung Universitätsmedizin Essen · University of Duisburg-Essen

    Affiliation as printed

    Cancer Research Center Cologne Essen (CCCE), University Medicine Essen (AöR), Hufelandstraße 55, 45147 Essen, Germany

    Center for Virtual and Extended Reality in Medicine (ZvRM), Essen University Hospital (AöR), Hufelandstraße 55, 45147 Essen, Germany

    Institute for Artificial Intelligence in Medicine (IKIM), Essen University Hospital (AöR), Girardetstraße 2, 45131 Essen, Germany

    University of Duisburg-Essen, Faculty of Computer Science, Schützenbahn 70, 45127 Essen, Germany

Cited by 11 stored of 11

11 results

No patents citing this paper on Lens.org (checked 2026-10-06).

References 21