Using cloud infrastructure to facilitate data collection and conversion of HLA diagnostic data for the 18th International HLA and Immunogenetics Workshop
HLA, vol. 101, pp. 484–495
Abstract
The International HLA and Immunogenetics Workshop (IHIW) is a recurring gathering of researchers, technologists and clinicians where participants contribute to collaborative projects with a variety of goals, and come to consensus on definitions and standards for representing HLA and immunogenic determinants. The collaborative and international nature of these workshops, combined with the multifaceted goals of several specific workshop components, necessitates the collection and curation of a wide assortment of data, as well as an adaptable platform for export and analysis. With the aim of ensuring data quality and creation of reusable datasets, specific standards and nomenclature conventions are continuously being developed, and are an integral part of IHIW. Here we present the 18th IHIW Database, a purpose-built and extensible cloud-based file repository and web application for collecting and analyzing project-specific data. This platform is based on open-source software and uses established HLA data standards and web technologies to facilitate de-centralized data repository ownership, reduce duplicated efforts, and promote continuity for future IHIWs.
Authors 8
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Benedict M. Matern corresponding
University Medical Center Utrecht
Affiliation as printed
Center for Translational Immunology UMC Utrecht Utrecht The Netherlands
Center for Translational Immunology, UMC Utrecht, Utrecht, The Netherlands
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Affiliation as printed
PIRCHE AG Berlin Germany
PIRCHE AG, Berlin, Germany
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Affiliation as printed
GenDx, Genome Diagnostics B.V. Utrecht The Netherlands
GenDx, Genome Diagnostics B.V., Utrecht, The Netherlands
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Affiliation as printed
PIRCHE AG Berlin Germany
PIRCHE AG, Berlin, Germany
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University Medical Center Utrecht
Affiliation as printed
Center for Translational Immunology UMC Utrecht Utrecht The Netherlands
Center for Translational Immunology, UMC Utrecht, Utrecht, The Netherlands
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Cynthia S. M. Kramer Aachen Department of Immunology Leiden University Medical Center Leiden The Netherlands Department of Immunology, Leiden University Medical Center
Leiden University Medical Center
Affiliation as printed
Department of Immunology Leiden University Medical Center Leiden The Netherlands
Department of Immunology, Leiden University Medical Center, Leiden, The Netherlands
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Sebastiaan Heidt Aachen Department of Immunology Leiden University Medical Center Leiden The Netherlands Department of Immunology, Leiden University Medical Center
Leiden University Medical Center
Affiliation as printed
Department of Immunology Leiden University Medical Center Leiden The Netherlands
Department of Immunology, Leiden University Medical Center, Leiden, The Netherlands
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University Medical Center Utrecht
Affiliation as printed
Center for Translational Immunology UMC Utrecht Utrecht The Netherlands
Central Diagnostics Laboratory UMC Utrecht Utrecht The Netherlands
Center for Translational Immunology, UMC Utrecht, Utrecht, The Netherlands
Central Diagnostics Laboratory, UMC Utrecht, Utrecht, The Netherlands
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