Learning Epistasis and Residue Coevolution Patterns: Current Trends and Future Perspectives for Advancing Enzyme Engineering

• Lessons learned on how to reengineer enzymes for improved performance in ionic liquids: insights from BSLA saturation mutagenesis library

  2026 Green Chemistry article Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization Open access

  1

  citations
• Capturing intrinsic protein dynamics for explaining beneficial substitutions from protein engineering campaigns

  2025 Biotechnology Advances article Biochemistry, Genetics and Molecular Biology Protein Structure and Dynamics

  5

  citations
• Global Dynamic Design (GDD) Empowers Cytochrome P450s for Improved Catalytic Performance

  2025 ACS Sustainable Chemistry & Engineering article Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization

  2

  citations
• Machine Learning-Assisted Engineering of Light, Oxygen, Voltage Photoreceptor Adduct Lifetime

  2023 JACS Au article Neuroscience Photoreceptor and optogenetics research Open access

  6

  citations
• Engineering of Substrate Tunnel of P450 CYP116B3 though Machine Learning

  2023 Catalysts article Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization Open access

  8

  citations

5 results

• Machine learning-assisted enzyme engineering

  2020 Methods in enzymology on CD-ROM/Methods in enzymology book-chapter Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization

  122

  citations
• PyPEF—An Integrated Framework for Data-Driven Protein Engineering

  2021 Journal of Chemical Information and Modeling article Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization

  39

  citations
• Chemogenetic Evolution of a Peroxidase-like Artificial Metalloenzyme

  2021 ACS Catalysis article Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization

  31

  citations
• Protein Engineering by Efficient Sequence Space Exploration Through Combination of Directed Evolution and Computational Design Methodologies

  2021 Protein Engineering other Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization

  13

  citations
• A hybrid model combining evolutionary probability and machine learning leverages data-driven protein engineering

  2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Protein Structure and Dynamics Open access

  11

  citations

5 results