Nanoparticle Diagnostics and Theranostics in the Clinic

Journal of Nuclear Medicine, vol. 63, pp. 1802–1808

Abstract

Nanoparticles possess unique features that may be useful for disease diagnosis and therapy. Preclinically, many different nanodiagnostics have been explored, but only a few have made it to the market. We here provide an overview of nanoparticle-based imaging agents currently used and evaluated in the clinic and discuss preclinical progress and translational avenues for the use of nanoparticles for diagnostic and theranostic applications.

Authors 5

1. Roger M. Pallares Aachen Institute for Experimental Molecular Imaging

   Universitätsklinikum Aachen · RWTH Aachen University

   Affiliation as printed

   Institute for Experimental Molecular Imaging, RWTH Aachen University Hospital, Aachen, Germany; rmoltopallar@ukaachen.de tlammers@ukaachen.de

   Institute for Experimental Molecular Imaging, RWTH Aachen University Hospital, Aachen, Germany

2. Felix Manuel Mottaghy Aachen Department of Nuclear Medicine

   Maastricht University Medical Centre · Maastricht University · Universitätsklinikum Aachen · RWTH Aachen University

   Affiliation as printed

   Department of Nuclear Medicine, RWTH Aachen University Hospital, Aachen, Germany

   Department of Radiology and Nuclear Medicine, Maastricht University Medical Center, Maastricht, The Netherlands; and

   Department of Radiology and Nuclear Medicine, Maastricht University Medical Center, Maastricht, The Netherlands

3. Volkmar Schulz Aachen Institute for Experimental Molecular Imaging Physics Institute III B

   Universitätsklinikum Aachen · RWTH Aachen University

   Affiliation as printed

   Institute for Experimental Molecular Imaging, RWTH Aachen University Hospital, Aachen, Germany

   Physics Institute III B, RWTH Aachen University, Aachen, Germany

4. Fabian M. Kiessling Aachen Institute for Experimental Molecular Imaging

   Universitätsklinikum Aachen · RWTH Aachen University

   Affiliation as printed

   Institute for Experimental Molecular Imaging, RWTH Aachen University Hospital, Aachen, Germany

5. Twan Lammers Aachen Institute for Experimental Molecular Imaging

   Universitätsklinikum Aachen · RWTH Aachen University

   Affiliation as printed

   Institute for Experimental Molecular Imaging, RWTH Aachen University Hospital, Aachen, Germany; rmoltopallar@ukaachen.de tlammers@ukaachen.de

   Institute for Experimental Molecular Imaging, RWTH Aachen University Hospital, Aachen, Germany