Structure protects function - An enabler for the functionalization of component surfaces by biohybrid coatings

Procedia CIRP, vol. 110, pp. 133–138

Abstract

The biological transformation is a growing part of current research in manufacturing and enables new possibilities in the development of innovative products. Modular functional assemblies based on biological building blocks potentially enable efficient and economical functionalization of component surfaces. Surface functionalization covers a range of industries and applications with high economic and technological potential and societal relevance. In dentistry, inflammation of the gums near the implant (periimplant infection) is one of the most common complications after implant implantation. The infections are mainly due to bacterial contamination or bacterial colonization at the implant. Biohybrid coatings based on modular functional assemblies represent an innovative solution for surface functionalization to prevent these periimplant infections. However, in addition to the advantages of modular functional assemblies, there are various challenges for the establishment of functional assemblies in series production. These pose new requirements for the manufacturing technology. The aim of interdisciplinary collaboration between biotechnology, soft matter nanotechnology, polymer chemistry, and production engineering is to provide implant surfaces (using titanium dental implants as an example) with an innovative biohybrid coating in combination with microstructuring. The coating prevents the bacterial colonization of the implant while the microstructure increases the robustness and longevity of the coating. The challenges in manufacturing these micro-structures of surfaces, the generation of biohybrid coatings as well as an outlook on the innovative use of functionalized surfaces are described in this paper.

Authors 10

1. Thomas Bergs Aachen Fraunhofer Institute for Production Technology IPT Laboratory for Machine Tools and Production Engineering (WZL)

   Fraunhofer Institute for Production Technology IPT · RWTH Aachen University

   Affiliation as printed

   Fraunhofer Institute for Production Technology IPT, Steinbachstr. 17, 52074 Aachen, Germany

   Laboratory for Machine Tools and Production Engineering (WZL) of RWTH Aachen University, Campus-Boulevard 30, 52074 Aachen, Germany

2. Ulrich Schwaneberg Aachen Chair of Biotechnology DWI-Leibniz-Institute for Interactive Materials e.V

   DWI – Leibniz Institute for Interactive Materials · RWTH Aachen University

   Affiliation as printed

   Chair of Biotechnology, RWTH Aachen University, Worringerweg 3, 52074 Aachen, Germany

   DWI - Leibniz Institute for Interactive Materials e.V., Forckenbeckstraße 50, 52074 Aachen, Germany

3. Sebastian Apelt corresponding Aachen Laboratory for Machine Tools and Production Engineering (WZL)

   RWTH Aachen University

   Affiliation as printed

   Laboratory for Machine Tools and Production Engineering (WZL) of RWTH Aachen University, Campus-Boulevard 30, 52074 Aachen, Germany

4. Felix Jakob Aachen DWI-Leibniz-Institute for Interactive Materials e.V

   DWI – Leibniz Institute for Interactive Materials

   Affiliation as printed

   DWI - Leibniz Institute for Interactive Materials e.V., Forckenbeckstraße 50, 52074 Aachen, Germany

5. César Rodriguez‐Emmenegger Aachen DWI-Leibniz-Institute for Interactive Materials e.V

   DWI – Leibniz Institute for Interactive Materials

   Affiliation as printed

   DWI - Leibniz Institute for Interactive Materials e.V., Forckenbeckstraße 50, 52074 Aachen, Germany

6. Alexander Beckers Aachen Laboratory for Machine Tools and Production Engineering (WZL)

   RWTH Aachen University

   Affiliation as printed

   Laboratory for Machine Tools and Production Engineering (WZL) of RWTH Aachen University, Campus-Boulevard 30, 52074 Aachen, Germany

7. Abdulkadir Yayci Aachen DWI-Leibniz-Institute for Interactive Materials e.V

   DWI – Leibniz Institute for Interactive Materials

   Affiliation as printed

   DWI - Leibniz Institute for Interactive Materials e.V., Forckenbeckstraße 50, 52074 Aachen, Germany

8. Maximilian Nöth Aachen Chair of Biotechnology

   RWTH Aachen University

   Affiliation as printed

   Chair of Biotechnology, RWTH Aachen University, Worringerweg 3, 52074 Aachen, Germany

9. Manuela Garay‐Sarmiento Aachen DWI-Leibniz-Institute for Interactive Materials e.V

   DWI – Leibniz Institute for Interactive Materials

   Affiliation as printed

   DWI - Leibniz Institute for Interactive Materials e.V., Forckenbeckstraße 50, 52074 Aachen, Germany

10. Sebastian Barth Aachen Laboratory for Machine Tools and Production Engineering (WZL)

    RWTH Aachen University

    Affiliation as printed

    Laboratory for Machine Tools and Production Engineering (WZL) of RWTH Aachen University, Campus-Boulevard 30, 52074 Aachen, Germany