R-ODAF: Omics data analysis framework for regulatory application

• Applicability of NAMs to support a read-across based hazard assessment workflow for systemic toxicity: a conazole case study

  2026 Archives of Toxicology article Veterinary Animal testing and alternatives Open access

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  citations
• Analytical choices drive toxicogenomic potency estimates: a systematic evaluation of transcriptomic points of departure

  2026 Toxicological Sciences article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access

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  citations
• Polyaromatic hydrocarbon driven developmental toxicity is dependent on the aryl hydrocarbon receptor: A case study with benzo(a)pyrene

  2026 Regulatory Toxicology and Pharmacology article Environmental Science Toxic Organic Pollutants Impact Open access

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  citations
• Systematic comparison of temporal hepatotoxicant-induced gene network responses across 3 liver test systems

  2026 Toxicological Sciences article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access

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  citations
• Discrimination of Steatotic and Non-Steatotic Chemicals Through Transcriptome Analysis in Primary Human Hepatocytes

  2026 International Journal of Molecular Sciences article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access

  1

  citations
• Quantitative adverse outcome pathway modeling of cisplatin-induced nephrotoxicity: developing in vitro and in vivo models for predictive extrapolation

  2026 Toxicological Sciences article Veterinary Animal testing and alternatives Open access

  1

  citations
• Advancing transcriptomics-based mechanistic assessment of nephrotoxicity in vitro using the human RPTEC/TERT1 TXG-MAPr gene co-expression network

  2025 Toxicological Sciences article Veterinary Animal testing and alternatives Open access

  2

  citations
• Mathematical modelling reveals compound-specific stress pathway activity

  2025 Toxicology article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access

  4

  citations
• Qualitative and quantitative concentration-response modelling of gene co-expression networks to unlock hepatotoxic mechanisms for next generation chemical safety assessment

  2024 ALTEX article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access

  5

  citations
• Qualitative and quantitative concentration-response modelling of gene co-expression networks to unlock hepatotoxic mechanisms for next generation chemical safety assessment_Suppl1

  2024 ALTEX article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access

  0

  citations
• Qualitative and quantitative concentration-response modelling of gene co-expression networks to unlock hepatotoxic mechanisms for next generation chemical safety assessment_Suppl5

  2024 ALTEX article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access

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• Qualitative and quantitative concentration-response modelling of gene co-expression networks to unlock hepatotoxic mechanisms for next generation chemical safety assessment_Suppl3

  2024 ALTEX article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access

  0

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• Qualitative and quantitative concentration-response modelling of gene co-expression networks to unlock hepatotoxic mechanisms for next generation chemical safety assessment_Suppl2

  2024 ALTEX article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access

  0

  citations
• Qualitative and quantitative concentration-response modelling of gene co-expression networks to unlock hepatotoxic mechanisms for next generation chemical safety assessment_Suppl6

  2024 ALTEX article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access

  0

  citations
• Qualitative and quantitative concentration-response modelling of gene co-expression networks to unlock hepatotoxic mechanisms for next generation chemical safety assessment_Suppl7

  2024 ALTEX article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access

  0

  citations
• Qualitative and quantitative concentration-response modelling of gene co-expression networks to unlock hepatotoxic mechanisms for next generation chemical safety assessment_Suppl8

  2024 ALTEX article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access

  0

  citations
• Systems toxicology to advance human and environmental hazard assessment: A roadmap for advanced materials

  2022 Nano Today article Environmental Science Environmental Toxicology and Ecotoxicology Open access

  25

  citations
• Multi-omics HeCaToS dataset of repeated dose toxicity for cardiotoxic & hepatotoxic compounds

  2022 Scientific Data data-paper Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access

  16

  citations

18 results