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The EHA Research Roadmap: Normal Hematopoiesis.

Utrecht University Repository (Utrecht University)

Abstract

In 2016, the European Hematology Association (EHA) published the EHA Roadmap for European Hematology Research1 aiming to highlight achievements in the diagnostics and treatment of blood disorders, and to better inform European policy makers and other stakeholders about the urgent clinical and scientific needs and priorities in the field of hematology. Each section was coordinated by 1–2 section editors who were leading international experts in the field. In the 5 years that have followed, advances in the field of hematology have been plentiful. As such, EHA is pleased to present an updated Research Roadmap, now including 11 sections, each of which will be published separately. The updated EHA Research Roadmap identifies the most urgent priorities in hematology research and clinical science, therefore supporting a more informed, focused, and ideally a more funded future for European hematology research. The 11 EHA Research Roadmap sections include Normal Hematopoiesis; Malignant Lymphoid Diseases; Malignant Myeloid Diseases; Anemias and Related Diseases; Platelet Disorders; Blood Coagulation and Hemostatic Disorders; Transfusion Medicine; Infections in Hematology; Hematopoietic Stem Cell Transplantation; CAR-T and Other Cell-based Immune Therapies; and Gene Therapy.

Authors 41

  1. Sorbonne Université · Laboratoire de Biologie du Développement · Institut de Biologie Paris-Seine

    Affiliation as printed

    Sorbonne Université, Institut de Biologie Paris Seine, Laboratoire de Biologie du Développement/UMR7622, Paris, France

  2. University of Pavia

    Affiliation as printed

    Department of Molecular Medicine, University of Pavia, Italy

  3. Instituto de Salud Carlos III · Josep Carreras Leukaemia Research Institute · Centro de Investigación Biomédica en Red de Cáncer

    Affiliation as printed

    Centro de Investigación Biomedica en Red-Oncología (CIBERONC), Instituto de Salud Carlos III, Madrid, Spain

    ISC - Instituto de Salud Carlos III [Madrid] (Carretera de Majadahonda - Pozuelo, 28220 Majadahonda, Madrid, Espagne - Spain)

    Josep Carreras Leukemia Research Institute (IJC), Barcelona, Spain

  4. IRCCS Ospedale San Raffaele

    Affiliation as printed

    IRCCS San Raffaele Scientific Institute [Milan, Italie] (Ospedale San Raffaele - Milano, via Olgettina 60, 20132 Milano, Italia - Italy)

  5. Affiliation as printed

    The Francis Crick Institute [London] (Mill Hill Laboratory, London - United Kingdom)

  6. Inserm · École Pratique des Hautes Études · Université Paris Cité · Université Paris Sciences et Lettres · HIPI - Immunologie humaine, physiopathologie et immunithérapie · Institut de recherche Saint-Louis

    Affiliation as printed

    INSERM U976, Universite de Paris, Ecole Pratique des Hautes Etudes/PSL Research University, Institut de Recherche Saint Louis, France

  7. Sorbonne Université · Laboratoire de Biologie du Développement · Institut de Biologie Paris-Seine

    Affiliation as printed

    Sorbonne Université, Institut de Biologie Paris Seine, Laboratoire de Biologie du Développement/UMR7622, Paris, France

  8. Inserm · Institut Pasteur · Université Paris Cité

    Affiliation as printed

    Unité Lymphopoïèse, Département d’Immunologie, INSERM U1223, Institut Pasteur, Cellule Pasteur, Université de Paris, France

  9. Erasmus MC

    Affiliation as printed

    Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands

  10. Sorbonne Université · Laboratoire de Biologie du Développement · Institut de Biologie Paris-Seine

    Affiliation as printed

    Sorbonne Université, Institut de Biologie Paris Seine, Laboratoire de Biologie du Développement/UMR7622, Paris, France

  11. Leiden University · Leiden University Medical Center

    Affiliation as printed

    LUMC - Leiden University Medical Center (Leids Universitair Medisch Centrum, Universiteit Leiden - 1233 ZA, Leiden - Netherlands)

  12. MRC Centre for Regenerative Medicine · University of Edinburgh

    Affiliation as printed

    Centre for Regenerative Medicine, Institute for Regeneration and Repair, University of Edinburgh, Scotland

  13. University of Verona

    Affiliation as printed

    Università degli Studi di Verona, Italy

  14. University of Cambridge · Cambridge University Press

    Affiliation as printed

    CAM - University of Cambridge [UK] (The Old Schools, Trinity Lane, Cambridge CB2 1TN - United Kingdom)

  15. Haukeland University Hospital · University of Bergen

    Affiliation as printed

    Department of Clinical Science, Centre for Cancer Biomarkers CCBIO, University of Bergen, Norway

    Department of Medicine, Hematology Section, Haukeland University Hospital, Bergen, Norway

  16. Wellcome/MRC Cambridge Stem Cell Institute · University of Cambridge

    Affiliation as printed

    Wellcome - MRC Cambridge Stem Cell Institute and Department of Haematology, University of Cambridge, United Kingdom

  17. Universitat Pompeu Fabra · Barcelona Institute of Science and Technology · Centre for Genomic Regulation

    Affiliation as printed

    Center for Genomic Regulation, Barcelona Institute for Science and Technology and Universitat Pompeu Fabra, Barcelona, Spain

  18. Princess Máxima Center

    Affiliation as printed

    Prinses Máxima Centrum voor kinderoncologie, Utecht, The Netherlands

  19. Université Paris Cité · Institut des Maladies Génétiques Imagine

    Affiliation as printed

    Department of Hematology and Laboratory of Physiopathology and Treatment of Blood Disorders, Hôpital Necker, Imagine institute, University of Paris, France

  20. John Radcliffe Hospital · University of Oxford

    Affiliation as printed

    John Radcliffe Hospital [Oxford University Hospital] (Headley Way, Headington, Oxford OX3 9DU - United Kingdom)

  21. Cyprus Institute of Neurology and Genetics

    Affiliation as printed

    Cyprus Institute of Neurology and Genetics (Nicosia Cyprus - Cyprus)

  22. Essen University Hospital

    Affiliation as printed

    Institute for Transfusion Medicine, University Hospital Essen, Germany

  23. University of Manchester

    Affiliation as printed

    University of Manchester [Manchester] (Oxford Rd, Manchester M13 9PL - United Kingdom)

  24. Goethe University Frankfurt · Georg Speyer Haus

    Affiliation as printed

    Goethe University Frankfurt and Georg-Speyer-Haus, Frankfurt am Main, Germany

  25. University of Manchester

    Affiliation as printed

    University of Manchester [Manchester] (Oxford Rd, Manchester M13 9PL - United Kingdom)

  26. Imperial College London

    Affiliation as printed

    Imperial College London (South Kensington Campus, London SW7 2AZ - United Kingdom)

  27. Radboud University Nijmegen · Radboud Institute for Molecular Life Sciences

    Affiliation as printed

    Department of Molecular Biology, RIMLS, Radboud University, Nijmegen, The Netherlands

  28. University of Cambridge · Cambridge University Press

    Affiliation as printed

    CAM - University of Cambridge [UK] (The Old Schools, Trinity Lane, Cambridge CB2 1TN - United Kingdom)

    NHSBT (France)

  29. Institució Catalana de Recerca i Estudis Avançats · Instituto de Salud Carlos III · Universitat de Barcelona

    Affiliation as printed

    Department of Biomedicine, School of Medicine, Universitat de Barcelona, Barcelona, Spain

    ISC - Instituto de Salud Carlos III [Madrid] (Carretera de Majadahonda - Pozuelo, 28220 Majadahonda, Madrid, Espagne - Spain)

    Institució Catalana de Recerca i Estudis Avancats (ICREA), Barcelona, Spain

    RICORS-RETAV, Instituto de Salud Carlos III, Madrid, Spain

    UB - Universitat de Barcelona (Gran Via de les Corts Catalanes, 585, 08007 Barcelona - Spain)

  30. Technical University of Munich

    Affiliation as printed

    Department of Internal Medicine III, Technical University of Munich, School of Medicine, Germany

  31. Erasmus MC · Erasmus University Rotterdam

    Affiliation as printed

    Department of Cell Biology, Erasmus University Medical Center Rotterdam, The Netherlands

  32. University of Copenhagen · Novo Nordisk Foundation · Rigshospitalet

    Affiliation as printed

    Biotech Research and Innovation Center (BRIC), University of Copenhagen, Denmark

    Novo Nordisk Foundation Center for Stem Cell Biology, DanStem, Faculty of Health Sciences, University of Copenhagen, Denmark

    The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Denmark

  33. Erasmus MC

    Affiliation as printed

    Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands

  34. University Medical Center Utrecht · Hubrecht Institute for Developmental Biology and Stem Cell Research

    Affiliation as printed

    Hubrecht Institute [Utrecht, Netherlands] (Uppsalalaan 8, 3584 CT Utrecht. - Netherlands)

    UMCU - University Medical Center [Utrecht] (Heidelberglaan 100 3584 CX Utrecht - Netherlands)

  35. Princess Máxima Center

    Affiliation as printed

    Prinses Máxima Centrum voor kinderoncologie, Utecht, The Netherlands

  36. University of Copenhagen · Novo Nordisk Foundation · Rigshospitalet

    Affiliation as printed

    Biotech Research and Innovation Center (BRIC), University of Copenhagen, Denmark

    Department of Hematology, Rigshospitalet/National University Hospital, University of Copenhagen, Denmark

    Novo Nordisk Foundation Center for Stem Cell Biology, DanStem, Faculty of Health Sciences, University of Copenhagen, Denmark

    The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Denmark

  37. Erasmus MC

    Affiliation as printed

    Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands

  38. Institut Gustave Roussy

    Affiliation as printed

    Gustave Roussy, Villejuif, France

  39. Josep Carreras Leukaemia Research Institute

    Affiliation as printed

    Red Blood Cell and Hematopoietic Disorders Research Unit, Institute for Leukaemia Research Josep Carreras, Badalona, Barcelona

  40. Sorbonne Université · Laboratoire de Biologie du Développement · Institut de Biologie Paris-Seine

    Affiliation as printed

    Sorbonne Université, Institut de Biologie Paris Seine, Laboratoire de Biologie du Développement/UMR7622, Paris, France

  41. University Medical Center Groningen · University of Groningen

    Affiliation as printed

    UMCG - University Medical Center Groningen [Groningen] (PO box 30.001 9700 RB Groningen - Netherlands)

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References 71