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January 29, 2022 article Open access Aachen paper

Process mining for healthcare: Characteristics and challenges

Journal of Biomedical Informatics, vol. 127, pp. 103994

DOI: 10.1016/j.jbi.2022.103994 Full text (OA) OpenAlex

Abstract

Process mining techniques can be used to analyse business processes using the data logged during their execution. These techniques are leveraged in a wide range of domains, including healthcare, where it focuses mainly on the analysis of diagnostic, treatment, and organisational processes. Despite the huge amount of data generated in hospitals by staff and machinery involved in healthcare processes, there is no evidence of a systematic uptake of process mining beyond targeted case studies in a research context. When developing and using process mining in healthcare, distinguishing characteristics of healthcare processes such as their variability and patient-centred focus require targeted attention. Against this background, the Process-Oriented Data Science in Healthcare Alliance has been established to propagate the research and application of techniques targeting the data-driven improvement of healthcare processes. This paper, an initiative of the alliance, presents the distinguishing characteristics of the healthcare domain that need to be considered to successfully use process mining, as well as open challenges that need to be addressed by the community in the future.

Authors 55

  1. Jorge Muñoz-Gama corresponding

    Pontificia Universidad Católica de Chile

    Affiliation as printed

    Pontificia Universidad Católica de Chile, Chile

  2. Niels Martin corresponding

    Research Foundation - Flanders · Hasselt University

    Affiliation as printed

    Hasselt University, Belgium; Research Foundation Flanders (FWO), Belgium

    Hasselt University, Belgium

    Research Foundation Flanders (FWO), Belgium

  3. Carlos Fernández-Llatas corresponding

    Karolinska Institutet · Universitat Politècnica de València

    Affiliation as printed

    Universitat Politècnica de València, Spain; Karolinska Institutet, Sweden

    Karolinska Institutet, Sweden

    Universitat Politècnica de València, Spain

  4. Owen Ashby Johnson corresponding

    University of Leeds

    Affiliation as printed

    University of Leeds, United Kingdom

  5. Marcos Sepúlveda corresponding

    Pontificia Universidad Católica de Chile

    Affiliation as printed

    Pontificia Universidad Católica de Chile, Chile

  6. Emmanuel Helm corresponding

    University of Applied Sciences Upper Austria

    Affiliation as printed

    University of Applied Sciences Upper Austria, Austria

  7. Víctor Galvez-Yanjari corresponding

    Pontificia Universidad Católica de Chile

    Affiliation as printed

    Pontificia Universidad Católica de Chile, Chile

  8. Eric Rojas

    Pontificia Universidad Católica de Chile

    Affiliation as printed

    Pontificia Universidad Católica de Chile, Chile

  9. Antonio Martínez-Millana

    Universitat Politècnica de València

    Affiliation as printed

    Universitat Politècnica de València, Spain

  10. Davide Aloini

    University of Pisa

    Affiliation as printed

    University of Pisa, Italy

  11. Ilaria Angela Amantea

    University of Luxembourg · University of Turin · University of Bologna

    Affiliation as printed

    University of Turin, Italy; University of Bologna, Italy; University of Luxembourg, Luxembourg

    University of Bologna, Italy

    University of Luxembourg, Luxembourg

    University of Turin, Italy

  12. Robert Andrews

    Queensland University of Technology

    Affiliation as printed

    Queensland University of Technology, Australia

  13. Michael Arias

    Universidad de Costa Rica

    Affiliation as printed

    Universidad de Costa Rica, Costa Rica

  14. Iris Beerepoot

    Utrecht University

    Affiliation as printed

    Utrecht University, The Netherlands

  15. Elisabetta Benevento

    University of Pisa

    Affiliation as printed

    University of Pisa, Italy

  16. Andrea Burattin

    Technical University of Denmark

    Affiliation as printed

    Technical University of Denmark, Denmark

  17. Daniel Capurro N

    The University of Melbourne

    Affiliation as printed

    University of Melbourne, Australia

  18. Josep Carmona

    Universitat Politècnica de Catalunya

    Affiliation as printed

    Universitat Politècnica de Catalunya, Spain

  19. Marco Comuzzi

    Ulsan National Institute of Science and Technology

    Affiliation as printed

    Ulsan National Institute of Science and Technology (UNIST), Republic of Korea

  20. Benjamin Dalmas

    Université Clermont Auvergne · Mines Saint-Étienne

    Affiliation as printed

    Mines Saint-Etienne, France; Université Clermont Auvergne, France

    Mines Saint-Etienne, France

    Université Clermont Auvergne, France

  21. René de la Fuente

    Pontificia Universidad Católica de Chile · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Hasselt University

    Affiliation as printed

    Pontificia Universidad Católica de Chile, Chile

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  22. Chiara Di Francescomarino

    Pontificia Universidad Católica de Chile · Fondazione Bruno Kessler · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Hasselt University

    Affiliation as printed

    Fondazione Bruno Kessler, Italy

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  23. Claudio Di Ciccio

    Pontificia Universidad Católica de Chile · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Sapienza University of Rome · Hasselt University

    Affiliation as printed

    Sapienza University of Rome, Italy

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  24. Roberto Gatta

    Centre Hospitalier Universitaire Vaudois · Philips (Netherlands) · University of Brescia

    Affiliation as printed

    Universitá degli Studi di Brescia, Italy; Lausanne University Hospital (CHUV), Switzerland

    Lausanne University Hospital (CHUV), Switzerland

    af Philips Research, the Netherlands

  25. Chiara Ghidini

    Pontificia Universidad Católica de Chile · Fondazione Bruno Kessler · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Hasselt University

    Affiliation as printed

    Fondazione Bruno Kessler, Italy

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  26. Fernanda Gonzalez-Lopez

    Pontificia Universidad Católica de Chile · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Hasselt University

    Affiliation as printed

    Pontificia Universidad Católica de Chile, Chile

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  27. Gema Ibáñez-Sánchez

    Pontificia Universidad Católica de Chile · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Hasselt University

    Affiliation as printed

    Universitat Politècnica de València, Spain

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  28. Hilda B. Klasky

    Oak Ridge National Laboratory · Pontificia Universidad Católica de Chile · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Hasselt University

    Affiliation as printed

    Oak Ridge National Laboratory, United States

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  29. Angelina Prima Kurniati

    Pontificia Universidad Católica de Chile · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Telkom University · Hasselt University

    Affiliation as printed

    Telkom University, Indonesia

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  30. Xixi Lu

    Pontificia Universidad Católica de Chile · Utrecht University · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Hasselt University

    Affiliation as printed

    Utrecht University, The Netherlands

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  31. Felix Mannhardt

    Pontificia Universidad Católica de Chile · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Eindhoven University of Technology · Hasselt University

    Affiliation as printed

    Eindhoven University of Technology, The Netherlands

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  32. Ronny S. Mans

    Pontificia Universidad Católica de Chile · Research Foundation - Flanders · Karolinska Institutet · Philips (Netherlands) · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Hasselt University

    Affiliation as printed

    Philips Research, the Netherlands

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  33. Mar Marcos

    Universitat Jaume I · Pontificia Universidad Católica de Chile

    Affiliation as printed

    Universitat Jaume I, Spain

    Pontificia Universidad Católica de Chile, Chile

  34. Renata Medeiros de Carvalho

    Pontificia Universidad Católica de Chile · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Eindhoven University of Technology · Hasselt University

    Affiliation as printed

    Eindhoven University of Technology, The Netherlands

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  35. Marco Pegoraro Aachen

    Ulsan National Institute of Science and Technology · RWTH Aachen University

    Affiliation as printed

    RWTH Aachen University, Germany

    Ulsan National Institute of Science and Technology (UNIST), Republic of Korea

  36. Simon Kar-Sing Poon

    The University of Sydney

    Affiliation as printed

    The University of Sydney, Australia

  37. Luise Pufahl

    Technische Universität Berlin · Technical University of Munich

    Affiliation as printed

    Technische Universitaet Berlin, Germany

    Technical University of Munich, Germany

  38. Hajo Alexander Reijers

    Pontificia Universidad Católica de Chile · Utrecht University · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Eindhoven University of Technology · Hasselt University

    Affiliation as printed

    Eindhoven University of Technology, The Netherlands; Utrecht University, The Netherlands

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  39. Simon Remy

    Pontificia Universidad Católica de Chile · University of Potsdam · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Hasselt University

    Affiliation as printed

    University of Potsdam, Germany

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  40. Stefanie Rinderle‐Ma

    Technical University of Munich

    Affiliation as printed

    Technical University of Munich, Germany

  41. Lucia Sacchi

    Pontificia Universidad Católica de Chile · University of Pavia · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Hasselt University

    Affiliation as printed

    University of Pavia, Italy

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  42. Fernando Seoane

    Karolinska University Hospital · Pontificia Universidad Católica de Chile · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Hasselt University · University of Borås

    Affiliation as printed

    Karolinska Institutet, Sweden; Karolinska University Hospital, Sweden; University of Borås, Sweden

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  43. Minseok Song

    Pohang University of Science and Technology

    Affiliation as printed

    Pohang University of Science and Technology, Republic of Korea

  44. Alessandro Stefanini

    University of Pisa · Pontificia Universidad Católica de Chile · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Hasselt University

    Affiliation as printed

    University of Pisa, Italy

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  45. Emilio Sulis

    Pontificia Universidad Católica de Chile · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · University of Turin · Universitat Politècnica de València · Hasselt University

    Affiliation as printed

    University of Turin, Italy

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  46. Arthur H. M. ter Hofstede

    Queensland University of Technology · Pontificia Universidad Católica de Chile · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Hasselt University

    Affiliation as printed

    Queensland University of Technology, Australia

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  47. Pieter Jelle Toussaint

    Norwegian University of Science and Technology · Mines Saint-Étienne · Technical University of Denmark

    Affiliation as printed

    Norwegian University of Science and Technology, Norway

    Technical University of Denmark, Denmark

    aj Mines Saint-Etienne, France

  48. Vicente Traver

    Pontificia Universidad Católica de Chile · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Hasselt University

    Affiliation as printed

    Universitat Politècnica de València, Spain

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  49. Zoe Valero-Ramón

    Pontificia Universidad Católica de Chile · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Hasselt University

    Affiliation as printed

    Universitat Politècnica de València, Spain

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  50. Inge van de Weerd

    Pontificia Universidad Católica de Chile · Utrecht University · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Hasselt University

    Affiliation as printed

    Utrecht University, The Netherlands

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  51. Wil M. P. van der Aalst Aachen

    Pontificia Universidad Católica de Chile · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Hasselt University · RWTH Aachen University

    Affiliation as printed

    RWTH Aachen University, Germany

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  52. Rob J. B. Vanwersch

    Queensland University of Technology · Eindhoven University of Technology

    Affiliation as printed

    Eindhoven University of Technology, The Netherlands

    Queensland University of Technology, Australia

  53. Mathias Weske

    Pontificia Universidad Católica de Chile · University of Potsdam · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Hasselt University

    Affiliation as printed

    University of Potsdam, Germany

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  54. Moe Thandar Wynn

    Queensland University of Technology · Pontificia Universidad Católica de Chile · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Hasselt University

    Affiliation as printed

    Queensland University of Technology, Australia

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

  55. Francesca Zerbato

    Pontificia Universidad Católica de Chile · University of St.Gallen · Research Foundation - Flanders · Karolinska Institutet · University of Applied Sciences Upper Austria · Universitat Politècnica de València · Hasselt University

    Affiliation as printed

    University of St. Gallen, Switzerland

    -Yanjari), Research Foundation Flanders (FWO), Belgium (N. Martin),

    Hasselt University, Belgium (N. Martin),

    Karolinska Institutet, Sweden (C. Fernandez-Llatas),

    Pontificia Universidad Católica de Chile (J

    Universitat Politècnica de València, Spain (C. Fernandez-Llatas),

    University of Applied Sciences Upper Austria, Austria

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References 182