An Artificial Phase‐Transitional Underwater Bioglue with Robust and Switchable Adhesion Performance
Angewandte Chemie International Edition, vol. 60, pp. 12082–12089
Abstract
Complex coacervation enables important wet adhesion processes in natural and artificial systems. However, existed synthetic coacervate adhesives show limited wet adhesion properties, non-thermoresponsiveness, and inferior biodegradability, greatly hampering their translations. Herein, by harnessing supramolecular assembly and rational protein design, we present a temperature-sensitive wet bioadhesive fabricated through recombinant protein and surfactant. Mechanical performance of the bioglue system is actively tunable with thermal triggers. In cold condition, adhesion strength of the bioadhesive was only about 50 kPa. By increasing temperature, the strength presented up to 600 kPa, which is remarkably stronger than other biological counterparts. This is probably due to the thermally triggered phase transition of the engineered protein and the formation of coacervate, thus leading to the enhanced wet adhesion bonding.
Authors 13
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University of Science and Technology of China · Chinese Academy of Sciences · Changchun Institute of Applied Chemistry · State Key Laboratory of Rare Earth Resources Utilization
Affiliation as printed
State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 China
University of Science and Technology of China Hefei 230026 China
State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022 China
These authors contributed equally to this work
University of Science and Technology of China, Hefei, 230026 China
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Jilin University · Chinese Academy of Sciences · Changchun Institute of Applied Chemistry · State Key Laboratory of Rare Earth Resources Utilization · Tsinghua University
Affiliation as printed
Department of Chemistry Tsinghua University Beijing 100084 China
Department of Urology China-Japan Union Hospital of Jilin University Changchun 130022 China
State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 China
Department of Chemistry, Tsinghua University, Beijing, 100084 China
Department of Urology, China-Japan Union Hospital of Jilin University, Changchun, 130022 China
State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022 China
These authors contributed equally to this work
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Chinese Academy of Sciences · Changchun Institute of Applied Chemistry · State Key Laboratory of Rare Earth Resources Utilization
Affiliation as printed
State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 China
State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022 China
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Chinese Academy of Sciences · Changchun Institute of Applied Chemistry · State Key Laboratory of Rare Earth Resources Utilization
Affiliation as printed
State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 China
State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022 China
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Affiliation as printed
Institute of Process Equipment College of Energy Engineering Zhejiang University Hangzhou 310027 China
Institute of Process Equipment, College of Energy Engineering, Zhejiang University, Hangzhou, 310027 China
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Affiliation as printed
School of Engineering and Applied Sciences Harvard University 29 Oxford Street Cambridge MA 02138 USA
School of Engineering and Applied Sciences, Harvard University, 29 Oxford Street, Cambridge, MA, 02138 USA
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Russian Academy of Sciences · Lomonosov Moscow State University · Semenov Institute of Chemical Physics
Affiliation as printed
Physics Department Lomonosov Moscow State University Moscow 119991 Russian Federation
Semenov Federal Research Center for Chemical Physics Russian Academy of Sciences 119991 Moscow Russian Federation
Physics Department, Lomonosov Moscow State University, Moscow, 119991 Russian Federation
Semenov Federal Research Center for Chemical Physics, Russian Academy of Sciences, 119991 Moscow, Russian Federation
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Affiliation as printed
Department of Urology China-Japan Union Hospital of Jilin University Changchun 130022 China
Department of Urology, China-Japan Union Hospital of Jilin University, Changchun, 130022 China
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Affiliation as printed
Institute of Process Equipment College of Energy Engineering Zhejiang University Hangzhou 310027 China
Institute of Process Equipment, College of Energy Engineering, Zhejiang University, Hangzhou, 310027 China
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Igor I. Potemkin Aachen
South Ural State University · Lomonosov Moscow State University · DWI – Leibniz Institute for Interactive Materials
Affiliation as printed
DWI—Leibniz Institute for Interactive Materials Forckenbeckstr. 50 52056 Aachen Germany
National Research South Ural State University 454080 Chelyabinsk Russian Federation
Physics Department Lomonosov Moscow State University Moscow 119991 Russian Federation
National Research South Ural State University, 454080 Chelyabinsk, Russian Federation
Physics Department, Lomonosov Moscow State University, Moscow, 119991 Russian Federation
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DWI – Leibniz Institute for Interactive Materials · RWTH Aachen University
Affiliation as printed
DWI—Leibniz Institute for Interactive Materials Forckenbeckstr. 50 52056 Aachen Germany
Institute of Technical and Macromolecular Chemistry RWTH Aachen University Worringerweg 1 52074 Aachen Germany
Institute of Technical and Macromolecular Chemistry, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany
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University of Science and Technology of China · Chinese Academy of Sciences · Changchun Institute of Applied Chemistry · State Key Laboratory of Rare Earth Resources Utilization · Tsinghua University
Affiliation as printed
Department of Chemistry Tsinghua University Beijing 100084 China
State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 China
University of Science and Technology of China Hefei 230026 China
Department of Chemistry, Tsinghua University, Beijing, 100084 China
State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022 China
University of Science and Technology of China, Hefei, 230026 China
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Kai Liu corresponding
University of Science and Technology of China · Chinese Academy of Sciences · Changchun Institute of Applied Chemistry · State Key Laboratory of Rare Earth Resources Utilization · Tsinghua University
Affiliation as printed
Department of Chemistry Tsinghua University Beijing 100084 China
State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 China
University of Science and Technology of China Hefei 230026 China
Department of Chemistry, Tsinghua University, Beijing, 100084 China
State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022 China
University of Science and Technology of China, Hefei, 230026 China
Cited by 79 stored of 79
Cited by patents worldwide 1 (Lens.org)
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