GPCRdb in 2021: integrating GPCR sequence, structure and function

• Large scale investigation of GPCR molecular dynamics data uncovers allosteric sites and lateral gateways

  2025 Nature Communications article Biochemistry, Genetics and Molecular Biology Receptor Mechanisms and Signaling Open access

  68

  citations
• Graph‐based algorithms to dissect long‐distance water‐mediated H‐bond networks for conformational couplings in GPCRs

  2024 British Journal of Pharmacology article Biochemistry, Genetics and Molecular Biology Receptor Mechanisms and Signaling Open access

  14

  citations
• Structure-Based Discovery of Mouse Trace Amine-Associated Receptor 5 Antagonists

  2023 Journal of Chemical Information and Modeling article Computer Science Computational Drug Discovery Methods Open access

  7

  citations
• Machine Learning-aided Discovery of Novel Chemotype Antagonists for G Protein-coupled Receptors: The Case of the Adenosine A 2A Receptor

  2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Computer Science Computational Drug Discovery Methods Open access

  2

  citations
• Molecular determinants of acrylamide neurotoxicity through covalent docking

  2023 Frontiers in Pharmacology article Agricultural and Biological Sciences Potato Plant Research Open access

  9

  citations
• Modeling the Orthosteric Binding Site of the G Protein-Coupled Odorant Receptor OR5K1

  2023 Journal of Chemical Information and Modeling article Biochemistry, Genetics and Molecular Biology Receptor Mechanisms and Signaling Open access

  30

  citations
• AI-based identification of therapeutic agents targeting GPCRs: introducing ligand type classifiers and systems biology

  2023 Chemical Science article Computer Science Computational Drug Discovery Methods Open access

  17

  citations
• A Chemical Biological Approach to Study G Protein-Coupled Receptors: Labeling the Adenosine A1 Receptor Using an Electrophilic Covalent Probe

  2022 ACS Chemical Biology article Biochemistry, Genetics and Molecular Biology Receptor Mechanisms and Signaling Open access

  14

  citations
• ADGRL1 haploinsufficiency causes a variable spectrum of neurodevelopmental disorders in humans and alters synaptic activity and behavior in a mouse model

  2022 The American Journal of Human Genetics article Biochemistry, Genetics and Molecular Biology Genetics and Neurodevelopmental Disorders Open access

  49

  citations
• Cancer-Associated Mutations of the Adenosine A2A Receptor Have Diverse Influences on Ligand Binding and Receptor Functions

  2022 Molecules article Biochemistry, Genetics and Molecular Biology Adenosine and Purinergic Signaling Open access

  7

  citations
• Modeling the Orthosteric Binding Site of the G Protein-Coupled Odorant Receptor OR5K1

  2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Receptor Mechanisms and Signaling Open access

  2

  citations
• FAIR Genomes metadata schema promoting Next Generation Sequencing data reuse in Dutch healthcare and research

  2022 Scientific Data data-paper Computer Science Research Data Management Practices Open access

  32

  citations

12 results