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Polymeric Nanoparticles: Polymeric Nanoparticles with Neglectable Protein Corona (Small 18/2020)

Small, vol. 16

Abstract

Currently it is assumed that each nanoparticle rapidly adsorbs proteins when it enters the living organism. However, this is not a general property of all nanosized drug delivery systems. In article number 1907574, Stefan Tenzer, Matthias Barz, Rudolf Zentel, and co-workers present three self-assembled polymeric structures, which are effectively free of a protein corona and additionally show prolonged circulation profiles in vivo.

Authors 16

  1. Johannes Gutenberg University Mainz

    Affiliation as printed

    Institute of Organic Chemistry Johannes Gutenberg University Mainz Duesbergweg 10‐14 Mainz D‐55128 Germany

    Institute of Organic Chemistry, Johannes Gutenberg University Mainz, Duesbergweg 10-14, Mainz, D-55128 Germany

  2. Johannes Gutenberg University Mainz

    Affiliation as printed

    Institute of Physical Chemistry Johannes Gutenberg University Mainz Duesbergweg 10‐14 Mainz D‐55128 Germany

    Institute of Physical Chemistry, Johannes Gutenberg University Mainz, Duesbergweg 10-14, Mainz, D-55128 Germany

  3. Cristal Therapeutics (Netherlands)

    Affiliation as printed

    Cristal Therapeutics Oxfordlaan 55 Maastricht 6229 EV The Netherlands

    Cristal Therapeutics, Oxfordlaan 55, Maastricht, 6229 EV The Netherlands

  4. Johannes Gutenberg University Mainz

    Affiliation as printed

    Institute of Organic Chemistry Johannes Gutenberg University Mainz Duesbergweg 10‐14 Mainz D‐55128 Germany

    Institute of Organic Chemistry, Johannes Gutenberg University Mainz, Duesbergweg 10-14, Mainz, D-55128 Germany

  5. University Medical Center of the Johannes Gutenberg University Mainz

    Affiliation as printed

    Institute for Immunology University Medical Center of Mainz Langenbeckstr. 1 Mainz 55131 Germany

    Institute for Immunology, University Medical Center of Mainz, Langenbeckstr. 1, Mainz, 55131 Germany

  6. Universitätsklinikum Aachen · RWTH Aachen University

    Affiliation as printed

    Department of Nanomedicine and Theranostics Institute for Experimental Molecular Imaging RWTH Aachen University Clinic Forckenbecktrasse 55 Aachen 52074 Germany

    Department of Nanomedicine and Theranostics, Institute for Experimental Molecular Imaging, RWTH Aachen University Clinic, Forckenbecktrasse 55, Aachen, 52074 Germany

  7. Universitätsklinikum Aachen · RWTH Aachen University

    Affiliation as printed

    Department of Nanomedicine and Theranostics Institute for Experimental Molecular Imaging RWTH Aachen University Clinic Forckenbecktrasse 55 Aachen 52074 Germany

    Department of Nanomedicine and Theranostics, Institute for Experimental Molecular Imaging, RWTH Aachen University Clinic, Forckenbecktrasse 55, Aachen, 52074 Germany

  8. Cristal Therapeutics (Netherlands)

    Affiliation as printed

    Cristal Therapeutics Oxfordlaan 55 Maastricht 6229 EV The Netherlands

    Cristal Therapeutics, Oxfordlaan 55, Maastricht, 6229 EV The Netherlands

  9. Universitätsklinikum Aachen · RWTH Aachen University

    Affiliation as printed

    Department of Nanomedicine and Theranostics Institute for Experimental Molecular Imaging RWTH Aachen University Clinic Forckenbecktrasse 55 Aachen 52074 Germany

    Department of Nanomedicine and Theranostics, Institute for Experimental Molecular Imaging, RWTH Aachen University Clinic, Forckenbecktrasse 55, Aachen, 52074 Germany

  10. University Medical Center of the Johannes Gutenberg University Mainz · Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg-Universität Mainz

    Affiliation as printed

    TRON ‐ Translational Oncology at the University Medical Center of Johannes Gutenberg University gGmbH Freiligrathstr. 12 Mainz 55131 Germany

    TRON - Translational Oncology at the University Medical Center of Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz, 55131 Germany

  11. Fraunhofer Institute for Microengineering and Microsystems

    Affiliation as printed

    Fraunhofer Institute for Microengineering and Microsystems IMM Carl‐Zeiss‐Str. 18‐20 Mainz 55129 Germany

    Fraunhofer Institute for Microengineering and Microsystems IMM, Carl-Zeiss-Str. 18-20, Mainz, 55129 Germany

  12. Max Planck Institute for Polymer Research

    Affiliation as printed

    Max Planck Institute for Polymer Research Ackermannweg 10 Mainz 55128 Germany

    Max Planck Institute for Polymer Research, Ackermannweg 10, Mainz, 55128 Germany

  13. Max Planck Institute for Polymer Research

    Affiliation as printed

    Max Planck Institute for Polymer Research Ackermannweg 10 Mainz 55128 Germany

    Max Planck Institute for Polymer Research, Ackermannweg 10, Mainz, 55128 Germany

  14. University Medical Center of the Johannes Gutenberg University Mainz

    Affiliation as printed

    Institute for Immunology University Medical Center of Mainz Langenbeckstr. 1 Mainz 55131 Germany

    Institute for Immunology, University Medical Center of Mainz, Langenbeckstr. 1, Mainz, 55131 Germany

  15. Johannes Gutenberg University Mainz

    Affiliation as printed

    Institute of Organic Chemistry Johannes Gutenberg University Mainz Duesbergweg 10‐14 Mainz D‐55128 Germany

    Institute of Organic Chemistry, Johannes Gutenberg University Mainz, Duesbergweg 10-14, Mainz, D-55128 Germany

  16. Johannes Gutenberg University Mainz

    Affiliation as printed

    Institute of Organic Chemistry Johannes Gutenberg University Mainz Duesbergweg 10‐14 Mainz D‐55128 Germany

    Institute of Organic Chemistry, Johannes Gutenberg University Mainz, Duesbergweg 10-14, Mainz, D-55128 Germany

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