Complement Inhibitors in Clinical Trials for Glomerular Diseases

• Targeted complement inhibition using bispecific antibodies that bind local antigens and endogenous complement regulators

  2024 Frontiers in Immunology article Immunology and Microbiology Complement system in diseases Open access cited by 1 patent

  11

  citations
• Moss-produced human complement factor H with modified glycans has an extended half-life and improved biological activity

  2024 Frontiers in Immunology article Immunology and Microbiology Complement system in diseases Open access cited by 2 patents

  16

  citations
• Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy

  2023 Nature Genetics article Medicine Renal Diseases and Glomerulopathies Open access

  191

  citations
• Lectin and alternative complement pathway activation in cutaneous manifestations of IgA-vasculitis: A new target for therapy?

  2022 Molecular Immunology article Immunology and Microbiology Complement system in diseases Open access

  20

  citations
• GWAS defines pathogenic signaling pathways and prioritizes drug targets for IgA nephropathy

  2021 medRxiv preprint Medicine Renal Diseases and Glomerulopathies Open access

  5

  citations
• Deposition of the Membrane Attack Complex in Healthy and Diseased Human Kidneys

  2021 Frontiers in Immunology article Immunology and Microbiology Complement system in diseases Open access

  84

  citations
• Precision medicine in immunoglobulin A nephropathy: still a journey ahead

  2021 Nephrology Dialysis Transplantation article Medicine Renal Diseases and Glomerulopathies Open access

  6

  citations
• Arteriolar C4d in IgA Nephropathy: A Cohort Study

  2020 American Journal of Kidney Diseases article Medicine Renal Diseases and Glomerulopathies Open access

  42

  citations

8 results