Drug repurposing: progress, challenges and recommendations

• PPP-COMPUTE: A Pandemic Pharmacology Platform for COMPUTational Evaluation of Anti-infectives in Pandemic Preparedness

  2026 medRxiv preprint Computer Science Computational Drug Discovery Methods Open access

  0

  citations
• Targeting chitinase-3-like protein-1 in pancolitis by a drug-repurposing approach

  2026 Biochemical Pharmacology article Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access

  0

  citations
• Primary human intestinal organoids model enteric infection of monkeypox virus and enable scalable drug discovery

  2026 Science Advances article Immunology and Microbiology Poxvirus research and outbreaks Open access

  3

  citations
• A phenotype-driven data and drug repurposing strategy used to identify potential treatments targeting chondrocyte hypertrophy in osteoarthritis

  2025 Biomedicine & Pharmacotherapy article Medicine Osteoarthritis Treatment and Mechanisms Open access

  0

  citations
• Primary human intestinal organoids recapitulate enteric infection of monkeypox virus and enable scalable drug discovery

  2025 medRxiv preprint Immunology and Microbiology Poxvirus research and outbreaks Open access

  3

  citations
• Restructuring knowledge graphs with conceptual models: implications for machine learning predictions in drug repurposing

  2025 Research Square preprint Computer Science Computational Drug Discovery Methods Open access

  0

  citations
• Restructuring Knowledge Graphs with Conceptual Models: Implications for Machine Learning Predictions in Drug Repurposing

  2025 Lecture notes in computer science conference-paper Computer Science Semantic Web and Ontologies Open access

  0

  citations
• Single-cell and genetic multi-omics analysis combined with experiments confirmed the signature and potential targets of cuproptosis in hepatocellular carcinoma

  2023 Frontiers in Cell and Developmental Biology article Medicine Ferroptosis and cancer prognosis Open access

  5

  citations
• Antidepressants as a potential candidate to reduce microglia activation in neurodegenerative diseases. A systematic review and meta-analysis of preclinical studies

  2023 Journal of Affective Disorders Reports review Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access

  8

  citations
• Nanomedicine for Treating Muscle Dystrophies: Opportunities, Challenges, and Future Perspectives

  2022 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access

  19

  citations
• Recent advances in metabolomics analysis for early drug development

  2022 Drug Discovery Today article Biochemistry, Genetics and Molecular Biology Metabolomics and Mass Spectrometry Studies Open access

  140

  citations
• Treatment with HIV-Protease Inhibitor Nelfinavir Identifies Membrane Lipid Composition and Fluidity as a Therapeutic Target in Advanced Multiple Myeloma

  2021 Cancer Research article Medicine Multiple Myeloma Research and Treatments Open access

  13

  citations
• Challenges and Opportunities for Drug Repositioning in Fibrodysplasia Ossificans Progressiva

  2021 Biomedicines article Medicine Heterotopic Ossification and Related Conditions Open access

  21

  citations

13 results