Unraveling the Complex Interplay Between T Cell Metabolism and Function

• Glutamine-driven mTORC1 activity enforces glycolytic bias, hyperactivation and aberrant proliferation in T cells in chronic B-cell leukemia

  2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism

  0

  citations
• CD27 costimulation supports metabolic fitness of CD4+ T cells by enhancing de novo nucleotide and protein synthesis

  2025 The Journal of Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access

  6

  citations
• Oleic acid triggers metabolic rewiring of T cells poising them for T helper 9 differentiation

  2024 iScience article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access

  18

  citations
• Oleic acid triggers CD4 + T cells to be metabolically rewired and poised to differentiate into proinflammatory T cell subsets upon activation

  2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access

  1

  citations
• A PD-1-ST2 axis controls Th2 effector function in tissue via a metabolic checkpoint

  2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology IL-33, ST2, and ILC Pathways Open access

  1

  citations
• Effects of fatty acids on T cell function: role in atherosclerosis

  2021 Nature Reviews Cardiology review Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access

  63

  citations
• Deficiency of the Circadian Clock Gene Bmal1 Reduces Microglial Immunometabolism

  2020 Frontiers in Immunology article Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access

  77

  citations

7 results