DIALS : implementation and evaluation of a new integration package

• Metabolic engineering of doxorubicin biosynthesis through P450-redox partner optimization and structural analysis of DoxA

  2026 Nature Communications article Medicine Microbial Natural Products and Biosynthesis Open access

  0

  citations
• The novel GlcNAc 6-phosphate dehydratase NagS governs a metabolic checkpoint that controls nutrient signaling in Streptomyces

  2025 PLoS Biology article Biochemistry, Genetics and Molecular Biology Bacterial Genetics and Biotechnology Open access

  0

  citations
• A new pathway in central metabolism mediates nutrient control of development and antibiotic production by Streptomyces

  2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Microbial Natural Products and Biosynthesis Open access

  2

  citations
• Bacterial esterases reverse lipopolysaccharide ubiquitylation to block host immunity

  2024 Cell Host & Microbe article Immunology and Microbiology Immune Response and Inflammation Open access

  32

  citations
• Estrogen Receptor α/14-3-3 molecular glues as alternative treatment strategy for endocrine resistant breast cancer

  2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Estrogen and related hormone effects Open access

  5

  citations
• Functional and structural asymmetry suggest a unifying principle for catalysis in membrane-bound pyrophosphatases

  2024 EMBO Reports article Biochemistry, Genetics and Molecular Biology ATP Synthase and ATPases Research Open access

  11

  citations
• Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors

  2023 Science article Computer Science Computational Drug Discovery Methods Open access

  191

  citations
• Cellular Validation of a Chemically Improved Inhibitor Identifies Monoubiquitination on OTUB2

  2023 ACS Chemical Biology article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access

  9

  citations
• The CCP 4 suite: integrative software for macromolecular crystallography

  2023 Acta Crystallographica Section D Structural Biology article Materials Science Enzyme Structure and Function Open access cited by 3 patents

  919

  citations
• Functional and structural asymmetry suggest a unifying principle for catalysis in integral membrane-bound pyrophosphatases

  2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology ATP Synthase and ATPases Research Open access

  2

  citations
• Chemical Toolkit for PARK7: Potent, Selective, and High-Throughput

  2022 Journal of Medicinal Chemistry article Medicine Parkinson's Disease Mechanisms and Treatments Open access cited by 1 patent

  16

  citations
• CCP 4 Cloud for structure determination and project management in macromolecular crystallography

  2022 Acta Crystallographica Section D Structural Biology article Materials Science Enzyme Structure and Function Open access cited by 2 patents

  89

  citations
• Crystal structures of BMPRII extracellular domain in binary and ternary receptor complexes with BMP10

  2022 Nature Communications article Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access

  23

  citations
• Synthesis of broad-specificity activity-based probes for exo -β-mannosidases

  2021 Organic & Biomolecular Chemistry article Chemistry Carbohydrate Chemistry and Synthesis Open access

  14

  citations
• CYP154C5 Regioselectivity in Steroid Hydroxylation Explored by Substrate Modifications and Protein Engineering**

  2020 ChemBioChem article Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization Open access

  25

  citations
• Structure of a GH51 α- L -arabinofuranosidase from Meripilus giganteus: conserved substrate recognition from bacteria to fungi

  2020 Acta Crystallographica Section D Structural Biology article Materials Science Enzyme Structure and Function Open access

  14

  citations
• Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown

  2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access

  149

  citations
• Identification and characterization of diverse OTU deubiquitinases in bacteria

  2020 The EMBO Journal article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access

  67

  citations
• Identification and characterization of diverse OTU deubiquitinases in bacteria

  2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access

  5

  citations

19 results