Daptomycin inhibits cell envelope synthesis by interfering with fluid membrane microdomains

• Bacterial cell envelope-targeting antibiotics

  2025 Nature Reviews Microbiology review Biochemistry, Genetics and Molecular Biology Antibiotic Resistance in Bacteria Open access

  31

  citations
• The stomatin-like protein StlP organizes membrane microdomains to govern polar growth in filamentous actinobacteria under hyperosmotic stress

  2025 Nature Communications article Biochemistry, Genetics and Molecular Biology Bacterial Genetics and Biotechnology Open access

  4

  citations
• Ticagrelor alters the membrane of Staphylococcus aureus and enhances the activity of vancomycin and daptomycin without eliciting cross-resistance

  2024 mBio article Medicine Antimicrobial Resistance in Staphylococcus Open access

  10

  citations
• Semisynthetic guanidino lipoglycopeptides with potent in vitro and in vivo antibacterial activity

  2024 Science Translational Medicine article Medicine Antimicrobial Resistance in Staphylococcus Open access

  26

  citations
• A classic antibiotic reimagined: Rationally designed bacitracin variants exhibit potent activity against vancomycin-resistant pathogens

  2024 Proceedings of the National Academy of Sciences article Immunology and Microbiology Antimicrobial Peptides and Activities Open access

  28

  citations
• Host defence peptide plectasin targets bacterial cell wall precursor lipid II by a calcium-sensitive supramolecular mechanism

  2024 Nature Microbiology article Immunology and Microbiology Antimicrobial Peptides and Activities Open access

  46

  citations
• Harzianic acid exerts antimicrobial activity against Gram-positive bacteria and targets the cell membrane

  2024 Frontiers in Microbiology article Medicine Microbial Natural Products and Biosynthesis Open access

  7

  citations
• A Clinically Selected Staphylococcus aureus clpP Mutant Survives Daptomycin Treatment by Reducing Binding of the Antibiotic and Adapting a Rod-Shaped Morphology

  2023 Antimicrobial Agents and Chemotherapy article Medicine Antimicrobial Resistance in Staphylococcus Open access

  16

  citations
• Novel determinant of antibiotic resistance: a clinically selected Staphylococcus aureus clpP mutant survives daptomycin treatment by reducing binding of the antibiotic and adapting a rod-shaped morphology

  2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Antimicrobial Resistance in Staphylococcus Open access

  2

  citations
• Classification of antimicrobial mechanism of action using dynamic bacterial morphology imaging

  2022 Scientific Reports article Chemistry Antimicrobial agents and applications Open access

  20

  citations
• Mechanistic insights into the C 55 -P targeting lipopeptide antibiotics revealed by structure–activity studies and high-resolution crystal structures

  2022 Chemical Science article Immunology and Microbiology Antimicrobial Peptides and Activities Open access

  24

  citations
• Harzianic Acid has multi-target antimicrobial activity against Gram-Positive Bacteria

  2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Microbial Natural Products and Biosynthesis Open access

  5

  citations
• Berkchaetoazaphilone B has antimicrobial activity and affects energy metabolism

  2021 Scientific Reports article Medicine Microbial Natural Products and Biosynthesis Open access

  5

  citations
• Structural studies on cell surface receptors and lipopeptide antibiotics

  2021 dissertation Biochemistry, Genetics and Molecular Biology Receptor Mechanisms and Signaling Open access

  0

  citations
• Classification of antimicrobial mechanism of action using bacterial time-lapse imaging

  2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Bacterial Genetics and Biotechnology Open access

  0

  citations
• Binding Studies Reveal Phospholipid Specificity and Its Role in the Calcium-Dependent Mechanism of Action of Daptomycin

  2021 ACS Infectious Diseases article Immunology and Microbiology Antimicrobial Peptides and Activities Open access

  49

  citations
• The Cell Envelope Stress Response of Bacillus subtilis towards Laspartomycin C

  2020 Antibiotics article Biochemistry, Genetics and Molecular Biology Bacterial Genetics and Biotechnology Open access

  13

  citations

17 results