A Tutorial on RxODE: Simulating Differential Equation Pharmacometric Models in R

• Toward optimal moxifloxacin dosing in tuberculous meningitis: A translational physiologically based pharmacokinetic modeling approach

  2026 European Journal of Pharmaceutical Sciences article Medicine Antibiotics Pharmacokinetics and Efficacy Open access

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• Toward optimal moxifloxacin dosing in tuberculous meningitis: a translational physiologically based pharmacokinetic modeling approach

  2025 medRxiv preprint Medicine Antibiotics Pharmacokinetics and Efficacy Open access

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• Dose Optimization of Vancomycin in Pediatric Post-Cardiac Surgery Patients: A Population Pharmacokinetic Modeling Study

  2024 Clinical Pharmacokinetics article Medicine Antibiotics Pharmacokinetics and Efficacy Open access

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  citations
• Exploring Kp,uu,BBB Values Smaller than Unity in Remoxipride: A Physiologically-Based CNS Model Approach Highlighting Brain Metabolism in Drugs with Passive Blood-Brain Barrier Transport

  2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Barrier Structure and Function Studies Open access

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• In vivo evolution of antimicrobial resistance in a biofilm model of Pseudomonas aeruginosa lung infection

  2024 The ISME Journal article Biochemistry, Genetics and Molecular Biology Bacterial biofilms and quorum sensing Open access

  40

  citations
• Revisiting Cerebrospinal Fluid Flow Direction and Rate in Physiologically Based Pharmacokinetic Model

  2022 Pharmaceutics article Neuroscience Cerebrospinal fluid and hydrocephalus Open access

  16

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• Population Pharmacokinetics of Flucloxacillin In Bone and Soft Tissue– Standard Dosing is Not Sufficient to Achieve Therapeutic Concentrations

  2022 Pharmaceutical Research article Medicine Antibiotics Pharmacokinetics and Efficacy

  10

  citations
• Design principles of collateral sensitivity-based dosing strategies

  2021 Nature Communications article Biochemistry, Genetics and Molecular Biology Evolution and Genetic Dynamics Open access

  63

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• Design principles of collateral sensitivity-based dosing strategies

  2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Evolution and Genetic Dynamics Open access

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• Population Pharmacokinetic and Pharmacogenetic Analysis of Mitotane in Patients with Adrenocortical Carcinoma: Towards Individualized Dosing

  2020 Clinical Pharmacokinetics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access

  13

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10 results