The macro domain is an ADP‐ribose binding module

• Dimerization of human PARP15 is required for NAD + binding and automodification

  2026 FEBS Journal article Medicine PARP inhibition in cancer therapy Open access

  0

  citations
• Parp7 generates an ADP-ribosyl degron that controls negative feedback of androgen signaling

  2025 The EMBO Journal article Medicine Prostate Cancer Treatment and Research Open access

  10

  citations
• Evolutionary and molecular basis of ADP-ribosylation reversal by zinc-dependent macrodomains

  2024 Journal of Biological Chemistry article Biochemistry, Genetics and Molecular Biology Biochemical and Molecular Research Open access

  8

  citations
• Pathological and physiological roles of ADP-ribosylation: established functions and new insights

  2024 Biological Chemistry article Medicine PARP inhibition in cancer therapy

  3

  citations
• Mono‐ADP‐Ribosylation of Peptides: An Overview of Synthetic and Chemoenzymatic Methodologies

  2024 ChemBioChem article Biochemistry, Genetics and Molecular Biology Chemical Synthesis and Analysis Open access

  6

  citations
• PARP14 is a PARP with both ADP-ribosyl transferase and hydrolase activities

  2023 Science Advances article Medicine PARP inhibition in cancer therapy Open access

  75

  citations
• PARP14 is a PARP with both ADP-ribosyl transferase and hydrolase activities

  2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine PARP inhibition in cancer therapy Open access

  4

  citations
• Intracellular mono-ADP-ribosyltransferases at the host–virus interphase

  2022 Cellular and Molecular Life Sciences article Immunology and Microbiology interferon and immune responses Open access

  31

  citations
• The search for inhibitors of macrodomains for targeting the readers and erasers of mono-ADP-ribosylation

  2021 Drug Discovery Today article Medicine PARP inhibition in cancer therapy

  21

  citations
• Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins

  2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Biochemical and Structural Characterization Open access cited by 2 patents

  90

  citations
• Comparative analysis of MACROD1, MACROD2 and TARG1 expression, localisation and interactome

  2020 Scientific Reports article Biochemistry, Genetics and Molecular Biology Cancer-related gene regulation Open access

  43

  citations
• The Controversial Roles of ADP-Ribosyl Hydrolases MACROD1, MACROD2 and TARG1 in Carcinogenesis

  2020 Cancers article Medicine PARP inhibition in cancer therapy Open access

  31

  citations

12 results