The Rotterdam Study: objectives and design update

• DNA methylation of genes involved in lipid metabolism drives adiponectin levels and metabolic disease

  2025 Diabetologia article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access

  7

  citations
• Identification of SENP7 and UTF1/VENTX as new loci influencing clustered protocadherin methylation across blood and brain using a genome-wide association study

  2025 Molecular Psychiatry article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access

  1

  citations
• Biomarkers of endothelial dysfunction and cognition: A two‐step IPD meta‐analysis

  2024 Alzheimer s & Dementia article Medicine Dementia and Cognitive Impairment Research Open access

  7

  citations
• Impact of QRS misclassifications on heart-rate-variability parameters (results from the CARLA cohort study)

  2024 PLoS ONE article Medicine Heart Rate Variability and Autonomic Control Open access

  1

  citations
• The inactive X chromosome accumulates widespread epigenetic variability with age

  2023 Clinical Epigenetics article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access

  22

  citations
• Metabolomic predictors of phenotypic traits can replace and complement measured clinical variables in population-scale expression profiling studies

  2022 BMC Genomics article Biochemistry, Genetics and Molecular Biology Metabolomics and Mass Spectrometry Studies Open access

  3

  citations
• Challenges at the APOE locus: a robust quality control approach for accurate APOE genotyping

  2022 Alzheimer s Research & Therapy article Medicine Alzheimer's disease research and treatments Open access

  23

  citations
• Circulating Metabolome and White Matter Hyperintensities in Women and Men

  2022 Circulation article Medicine Cerebrovascular and genetic disorders Open access

  41

  citations
• Functional genomics analysis identifies T and NK cell activation as a driver of epigenetic clock progression

  2022 Genome biology article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access cited by 1 patent

  71

  citations
• Challenges at the APOE locus: A robust quality control approach for accurate APOE genotyping

  2021 medRxiv preprint Medicine Alzheimer's disease research and treatments Open access

  2

  citations
• Rare and low-frequency exonic variants and gene-by-smoking interactions in pulmonary function

  2021 Scientific Reports article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  5

  citations
• Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFNγ Signaling in Celiac Disease

  2021 Frontiers in Genetics article Medicine Celiac Disease Research and Management Open access cited by 1 patent

  48

  citations
• Prevalence of Monogenic Bone Disorders in a Dutch Cohort of Atypical Femur Fracture Patients

  2020 Journal of Bone and Mineral Research article Medicine Bone health and osteoporosis research Open access

  19

  citations
• Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids

  2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  61

  citations
• Serum fatty acid chain length associates with prevalent symptomatic end-stage osteoarthritis, independent of BMI

  2020 Scientific Reports article Medicine Osteoarthritis Treatment and Mechanisms Open access

  14

  citations
• Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference

  2020 Genome biology article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access cited by 1 patent

  41

  citations
• Long-term prognosis after kidney donation: a propensity score matched comparison of living donors and non-donors from two population cohorts

  2020 European Journal of Epidemiology article Medicine Organ Donation and Transplantation Open access

  33

  citations
• CDH6 and HAGH protein levels in plasma associate with Alzheimer’s disease in APOE ε4 carriers

  2020 Scientific Reports article Medicine Dementia and Cognitive Impairment Research Open access

  31

  citations
• The Aging Imageomics Study: rationale, design and baseline characteristics of the study population

  2020 Mechanisms of Ageing and Development article Medicine Dementia and Cognitive Impairment Research Open access cited by 2 patents

  33

  citations
• The role of gene expression on human sexual dimorphism: too early to call

  2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  3

  citations

20 results