Mouse Models for Atherosclerosis and Pharmaceutical Modifiers

• Efficacy of a novel PCSK9 inhibitory peptide alone and with evinacumab in a mouse model of atherosclerosis

  2025 Journal of Lipid Research article Medicine Lipoproteins and Cardiovascular Health Open access

  6

  citations
• Silencing of the von Willebrand factor gene in proatherothrombotic APOE∗3-Leiden.CETP transgenic mice

  2025 Research and Practice in Thrombosis and Haemostasis article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access

  1

  citations
• Liver-targeted Angptl4 silencing by antisense oligonucleotide treatment attenuates hyperlipidaemia and atherosclerosis development in APOE*3-Leiden.CETP mice

  2024 Cardiovascular Research article Medicine Lipid metabolism and disorders Open access

  17

  citations
• Atherosclerosis: an overview of mouse models and a detailed methodology to quantify lesions in the aortic root

  2024 Vascular Biology article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access

  14

  citations
• Atorvastatin Attenuates Diet-Induced Non-Alcoholic Steatohepatitis in APOE*3-Leiden Mice by Reducing Hepatic Inflammation

  2023 International Journal of Molecular Sciences article Medicine Liver Disease Diagnosis and Treatment Open access

  16

  citations
• Validating human and mouse tissues commonly used in atherosclerosis research with coronary and aortic reference tissue: similarities but profound differences in disease initiation and plaque stability

  2023 JVS Vascular Science article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access

  6

  citations
• Lipid profiling analyses from mouse models and human infants

  2022 STAR Protocols article Biochemistry, Genetics and Molecular Biology Metabolomics and Mass Spectrometry Studies Open access

  8

  citations
• Phosphorylcholine antibodies restrict infarct size and left ventricular remodelling by attenuating the unreperfused post‐ischaemic inflammatory response

  2021 Journal of Cellular and Molecular Medicine article Medicine Cardiac Fibrosis and Remodeling Open access

  6

  citations
• Atherothrombosis model by silencing of protein C in APOE*3-Leiden.CETP transgenic mice

  2021 Journal of Thrombosis and Thrombolysis article Medicine Blood Coagulation and Thrombosis Mechanisms Open access

  6

  citations
• Novel high-intensive cholesterol-lowering therapies do not ameliorate knee OA development in humanized dyslipidemic mice

  2021 Osteoarthritis and Cartilage article Medicine Osteoarthritis Treatment and Mechanisms Open access

  13

  citations
• Beneficial effects of brown fat activation on top of PCSK9 inhibition with alirocumab on dyslipidemia and atherosclerosis development in APOE*3-Leiden.CETP mice

  2021 Pharmacological Research article Medicine Lipoproteins and Cardiovascular Health Open access

  18

  citations
• Hepatic Scavenger Receptor Class B Type 1 Knockdown Reduces Atherosclerosis and Enhances the Antiatherosclerotic Effect of Brown Fat Activation in APOE*3-Leiden.CETP Mice

  2021 Arteriosclerosis Thrombosis and Vascular Biology article Medicine Cholesterol and Lipid Metabolism Open access

  11

  citations
• Lipid ratios representing SCD1, FADS1, and FADS2 activities as candidate biomarkers of early growth and adiposity

  2021 EBioMedicine article Biochemistry, Genetics and Molecular Biology Lipid metabolism and biosynthesis Open access

  23

  citations
• Effects on cardiac function, remodeling and inflammation following myocardial ischemia–reperfusion injury or unreperfused myocardial infarction in hypercholesterolemic APOE*3-Leiden mice

  2020 Scientific Reports article Medicine Cardiac Fibrosis and Remodeling Open access

  27

  citations
• Role of homeostatic iron regulator protein in hepatic cholesterol metabolism: interaction between Kupffer cells and hepatocytes?

  2020 European Heart Journal article Medicine Cholesterol and Lipid Metabolism Open access

  3

  citations

15 results