CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

• Deciphering the regulatory landscape of enhancer RNAs in health and disease

  2026 Signal Transduction and Targeted Therapy article Biochemistry, Genetics and Molecular Biology Cancer-related molecular mechanisms research Open access

  10

  citations
• Identification of a SNAI1 enhancer RNA that drives cancer cell plasticity

  2025 Nature Communications article Biochemistry, Genetics and Molecular Biology Cancer-related molecular mechanisms research Open access

  9

  citations
• On RNA-programmable gene modulation as a versatile set of principles targeting muscular dystrophies

  2024 Molecular Therapy article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access

  7

  citations
• The lncRNA LETS1 promotes TGF-β–induced EMT and cancer cell migration by transcriptionally activating a TβR1-stabilizing mechanism

  2023 Science Signaling article Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access

  30

  citations
• A Versatile Clustered Regularly Interspaced Palindromic Repeats Toolbox to Study Neurological CaV3.2 Channelopathies by Promoter-Mediated Transcription Control

  2022 Frontiers in Molecular Neuroscience article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access cited by 1 patent

  2

  citations
• CRISPR/Cas9 editing in conditionally immortalized HoxB8 cells for studying gene regulation in mouse dendritic cells

  2021 European Journal of Immunology article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access

  13

  citations
• CRISPR and KRAS: a match yet to be made

  2021 Journal of Biomedical Science article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access cited by 1 patent

  22

  citations
• Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element

  2021 The American Journal of Human Genetics article Biochemistry, Genetics and Molecular Biology Genomics and Chromatin Dynamics Open access

  9

  citations
• A versatile CRISPR toolbox to study neurological Ca V 3.2 channelopathies by promoter-mediated transcription control

  2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access

  1

  citations
• FAM72, Glioblastoma Multiforme (GBM) and Beyond

  2021 Cancers article Medicine Glioma Diagnosis and Treatment Open access

  20

  citations
• Comprehensive Mapping of Key Regulatory Networks that Drive Oncogene Expression

  2020 Cell Reports article Biochemistry, Genetics and Molecular Biology Genomics and Chromatin Dynamics Open access

  18

  citations

11 results