Scale‐down models to optimize a filter train for the downstream purification of recombinant pharmaceutical proteins produced in tobacco leaves

• Optimizing interleukin-6 and 8 expression, clarification and purification in plant cell packs and plants for application in advanced therapy medicinal products and cellular agriculture

  2024 Journal of Biotechnology article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access

  11

  citations
• Membrane-based inverse-transition purification facilitates a rapid isolation of various spider-silk elastin-like polypeptide fusion proteins from extracts of transgenic tobacco

  2024 Transgenic Research article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access

  7

  citations
• Design, optimization, production and activity testing of recombinant immunotoxins expressed in plants and plant cells for the treatment of monocytic leukemia

  2023 Bioengineered article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access

  14

  citations
• Risk assessment and bioburden evaluation of Agrobacterium tumefaciens-mediated transient protein expression in plants using the CaMV35S promoter

  2023 BMC Biotechnology article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access

  7

  citations
• Killer to cure: Expression and production costs calculation of tobacco plant‐made cancer‐immune checkpoint inhibitors

  2023 Plant Biotechnology Journal article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access

  28

  citations
• The use of antifoam agents to eliminate bubbles during biotechnological sample analysis

  2023 Discover Chemical Engineering article Biochemistry, Genetics and Molecular Biology Protein purification and stability Open access

  3

  citations
• Production of Complex Proteins in Plants: From Farming to Manufacturing

  2023 Cell engineering book-chapter Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications

  2

  citations
• Simple plant‐based production and purification of the assembled human ferritin heavy chain as a nanocarrier for tumor‐targeted drug delivery and bioimaging in cancer therapy

  2022 Biotechnology and Bioengineering article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access

  30

  citations
• Bayesian optimization using multiple directional objective functions allows the rapid inverse fitting of parameters for chromatography simulations

  2022 Journal of Chromatography A article Chemistry Analytical Chemistry and Chromatography Open access

  24

  citations
• Reducing water uptake into BY‐2 cells by systematically optimizing the cultivation parameters increases product yields achieved by transient expression in plant cell packs

  2022 Biotechnology Journal article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access cited by 1 patent

  10

  citations
• Strategies for Efficient and Sustainable Protein Extraction and Purification from Plant Tissues

  2022 Methods in molecular biology book-chapter Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications

  9

  citations
• Expression of Biofilm-Degrading Enzymes in Plants and Automated High-Throughput Activity Screening Using Experimental Bacillus subtilis Biofilms

  2021 Frontiers in Bioengineering and Biotechnology article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access

  10

  citations
• A combined pH and temperature precipitation step facilitates the purification of tobacco‐derived recombinant proteins that are sensitive to extremes of either parameter

  2020 Biotechnology Journal article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access

  28

  citations
• Robot Cookies – Plant Cell Packs as an Automated High-Throughput Screening Platform Based on Transient Expression

  2020 Frontiers in Bioengineering and Biotechnology article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access

  53

  citations

14 results