Platforms for antibiotic discovery

• Discovery and Derivatization of Tridecaptin Antibiotics with Altered Host Specificity and Enhanced Bioactivity

  2024 ACS Chemical Biology article Medicine Microbial Natural Products and Biosynthesis Open access

  9

  citations
• Recent Advances in the Development of Polymyxin Antibiotics: 2010–2023

  2024 ACS Infectious Diseases article Immunology and Microbiology Antimicrobial Peptides and Activities Open access cited by 2 patents

  69

  citations
• Semisynthetic polymyxins with potent antibacterial activity and reduced kidney cell toxicity

  2023 RSC Medicinal Chemistry article Chemistry Antimicrobial agents and applications Open access

  6

  citations
• The ubiquitous catechol moiety elicits siderophore and angucycline production in Streptomyces

  2022 Communications Chemistry article Medicine Microbial Natural Products and Biosynthesis Open access

  31

  citations
• Expansion of RiPP biosynthetic space through integration of pan-genomics and machine learning uncovers a novel class of lanthipeptides

  2020 PLoS Biology article Medicine Microbial Natural Products and Biosynthesis Open access cited by 2 patents

  131

  citations
• A VersaTile-driven platform for rapid hit-to-lead development of engineered lysins

  2020 Science Advances article Environmental Science Bacteriophages and microbial interactions Open access cited by 8 patents

  143

  citations
• Integration of machine learning and pan-genomics expands the biosynthetic landscape of RiPP natural products

  2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Microbial Natural Products and Biosynthesis Open access

  5

  citations

7 results