Mycobacterium tuberculosis Peptides Presented by HLA-E Molecules Are Targets for Human CD8+ T-Cells with Cytotoxic as well as Regulatory Activity

• Conformation of HLA-E/peptide complex guides interaction with two novel HLA-E receptors: Stabilin 1 and 2

  2025 PLoS ONE article Immunology and Microbiology Immune Cell Function and Interaction Open access

  3

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• HLA-E/peptide complexes differentially interact with NKG2A/CD94 and T cell receptors

  2025 The Journal of Immunology article Immunology and Microbiology Immune Cell Function and Interaction Open access

  10

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• HLA-E/Mtb specific CD4+ and CD8+ T cells have a memory phenotype in individuals with TB infection

  2024 Frontiers in Immunology article Medicine Tuberculosis Research and Epidemiology Open access

  4

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• Mtb specific HLA-E restricted T cells are induced during Mtb infection but not after BCG administration in non-human primates and humans

  2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Tuberculosis Research and Epidemiology Open access

  1

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• Mtb HLA-E-tetramer-sorted CD8+ T cells have a diverse TCR repertoire

  2024 iScience article Immunology and Microbiology T-cell and B-cell Immunology Open access

  8

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• The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent

  2023 Cell Reports article Immunology and Microbiology Immune Cell Function and Interaction Open access

  20

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• Extensive flow cytometric immunophenotyping of human PBMC incorporating detection of chemokine receptors, cytokines and tetramers

  2023 Cytometry Part A article Immunology and Microbiology T-cell and B-cell Immunology Open access

  14

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• Thermal‐exchange HLA‐E multimers reveal specificity in HLA‐E and NKG2A / CD94 complex interactions

  2022 Immunology article Biochemistry, Genetics and Molecular Biology vaccines and immunoinformatics approaches Open access

  9

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• Identification of HLA-E Binding Mycobacterium tuberculosis–Derived Epitopes through Improved Prediction Models

  2022 The Journal of Immunology article Biochemistry, Genetics and Molecular Biology vaccines and immunoinformatics approaches Open access

  21

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• Antigen presentation by MHC-E: a putative target for vaccination?

  2022 Trends in Immunology review Biochemistry, Genetics and Molecular Biology vaccines and immunoinformatics approaches Open access

  33

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• Discovery of HLA-E-Presented Epitopes: MHC-E/Peptide Binding and T-Cell Recognition

  2022 Methods in molecular biology book-chapter Biochemistry, Genetics and Molecular Biology vaccines and immunoinformatics approaches Open access

  13

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• All mycobacteria are inventive, but some are more Daedalean than others

  2021 Immunological Reviews review Medicine Tuberculosis Research and Epidemiology Open access

  1

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• The role of donor‐unrestricted T‐cells, innate lymphoid cells, and NK cells in anti‐mycobacterial immunity

  2021 Immunological Reviews review Medicine Tuberculosis Research and Epidemiology Open access

  44

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• Conventional and Unconventional Lymphocytes in Immunity Against Mycobacterium tuberculosis

  2020 Springer eBooks book-chapter Medicine Tuberculosis Research and Epidemiology

  0

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• Peptide Binding to HLA-E Molecules in Humans, Nonhuman Primates, and Mice Reveals Unique Binding Peptides but Remarkably Conserved Anchor Residues

  2020 The Journal of Immunology article Biochemistry, Genetics and Molecular Biology vaccines and immunoinformatics approaches Open access cited by 1 patent

  38

  citations

15 results