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Ion channel regulation and function Sign in to save
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Papers 97
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The Potential Effect of Nav1.8 in Autism Spectrum Disorder: Evidence From a Congenital Case With Compound Heterozygous SCN10A Mutations2021 Frontiers in Molecular Neuroscience article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Björn Heinrichs, Baowen Liu, Jin Zhang, Jannis Meents, Kim Huyen Trang Le, Andelain Erickson, +10 more
4citations -
Safety, Pharmacokinetics, and Pharmacodynamics of a First‐in‐Class ClC ‐1 Inhibitor to Enhance Muscle Excitability: Phase I Randomized Controlled Trial2024 Clinical Pharmacology & Therapeutics article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Titia Q. Ruijs, Catherine M.K.E. de Cuba, Jules A. A. C. Heuberger, Jane Bold, Thomas Skjærlund Grønnebæk, Klaus Gjervig Jensen, +13 more
4citations -
Kir7.1 is the physiological target for hormones and steroids that regulate uteroplacental function2025 Science Advances article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Monika Haoui, Citlalli Vergara, Lina Kenzler, Geraldine Zimmer‐Bensch, David Fleck, Christopher Wiesbrock, +2 more
3citations -
The second PI(3,5)P2 binding site in the S0 helix of KCNQ1 stabilizes PIP2-at the primary PI1 site with potential consequences on intermediate-to-open state transition2023 Biological Chemistry article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function
Maurice Dellin, Ina Rohrbeck, Purva Asrani, Julian Alexander Schreiber, Nadine Ritter, Frank Glorius, +14 more
3citations -
Mechanisms of Glioblastoma Replication: Ca2+ Flares and Cl− Currents2024 Molecular Cancer Research article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function cited by 1 patent
Yunzhen Li, Cesar Adolfo Sánchez Triviño, Andres Hernandez, Simone Mortal, Federica Spada, Ilona Krivosheia, +8 more
3citations -
Loss-of-function variants in the KCNQ5 gene are associated with genetic generalized epilepsies2021 medRxiv preprint Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Johanna Krüger, Julian Schubert, Josua Kegele, Audrey Labalme, Miaomiao Mao, Jacqueline Heighway, +15 more
3citations -
Modulating effects of FGF12 variants on Na V 1.2 and Na V 1.6 associated with Developmental and Epileptic Encephalopathy and Autism Spectrum Disorder2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Simone Seiffert, Manuela Pendziwiat, Tatjana Bierhals, Himanshu Goel, Niklas Schwarz, Amelie T. van der Ven, +5 more
2citations -
Carriers of SCN9A variants linked to inherited and acquired pain syndromes show no alteration in the prevalence of pain or analgesic usage in the UK Biobank cohort2025 medRxiv preprint Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Graeme W. T. Newton, Corin Charman, Aidan P. Nickerson, Keith Geoffrey Phillips, Achim Kless, James Philip Dunham, +1 more
2citations -
Disruption of ClC-3-mediated 2Cl−/H+ exchange leads to behavioural deficits and thalamic atrophy2025 Scientific Reports article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Carina Balduin, Guanxiao Qi, Michael Schöneck, Verena Trinkel, Sarah Schemmert, Gustavo A. Guzman, +9 more
1citations -
Altered NaV1.9 channel activity in two Tyr66Ser variant carriers with small fiber dysfunction2025 The Journal of General Physiology article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function
Noortje W.M. van den Braak, Samuel Kuehs, Greta Z. Peschke, Barbara Namer, Annette Lischka, Katja Eggermann, +10 more
1citations -
α‐Adrenoreceptor blocker phentolamine inhibits voltage‐gated sodium channels via the local anaesthetic binding site2025 British Journal of Pharmacology article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Idil Toklucu, Vishal Sudha Bhagavath Eswaran, Raya Bott, Aylin Bilge Kesdoğan, Arnim Johannes Gaebler, Julia Stingl, +3 more
1citations -
Phentolamine selectively blocks C-fiber conduction in different species, including humans2025 Regional Anesthesia & Pain Medicine article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function
Stanislav Koulchitsky, Andelain Erickson, Tal Hoffmann, Idil Toklucu, Raya Bott, Jannis Körner, +9 more
1citations -
High-throughput electrophysiology reveals subtype specific temperature dependence of sodium channel activation and inactivation2022 Biophysical Journal article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Sophia Kriegeskorte, Raya Bott, Ralf Hausmann, Angelika Lampert
1citations -
Sodium channels expressed in nociceptors contribute distinctly to action potential subthreshold phase, upstroke and shoulder2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Phil Alexander Köster, Enrico Leipold, Anna Maxion, Barbara Namer, Thomas Stiehl, Angelika Lampert
1citations -
Specific presynaptic functions require distinct Drosophila Cav2 splice isoforms2024 eLife preprint Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Lukas Kilo, Daniel Gottschalk, Jashar Arian, Lea Deneke, Christof Rickert, Oliver Kobler, +3 more
1citations -
SAFETY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF A CLC-1 INHIBITOR - A FIRST-IN-CLASS COMPOUND THAT ENHANCES MUSCLE EXCITABILITY: A PHASE I, SINGLE- AND MULTIPLE-ASCENDING DOSE STUDY2024 medRxiv preprint Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Titia Q. Ruijs, Catherine M.K.E. de Cuba, Jules A. A. C. Heuberger, Jane Bold, Thomas Groennebaek, Klaus Gjervig Jensen, +12 more
1citations
Most active Aachen authors
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Angelika Lampert 4,522 citations overall29 papers
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Ralf Hausmann 2,621 citations overall10 papers
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Jannis Körner 274 citations overall9 papers
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Jannis Meents 955 citations overall7 papers
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Petra A. I. Hautvast 647 citations overall7 papers
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Vishal Sudha Bhagavath Eswaran 116 citations overall7 papers
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Giulia Rossetti 3,028 citations overall6 papers
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Raya Bott 120 citations overall6 papers
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Lukas Kilo 59 citations overall6 papers
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Ingo Kurth 13,878 citations overall5 papers
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Marc Spehr 5,894 citations overall5 papers
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Geert Jan Groeneveld 5,330 citations overall5 papers
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Barbara Namer 3,378 citations overall5 papers
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Jules A. A. C. Heuberger 1,618 citations overall5 papers
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Jan‐Philipp Machtens 1,012 citations overall5 papers