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Complement system in diseases Sign in to save
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Papers 197
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Use of eculizumab in children with allogeneic haematopoietic stem cell transplantation associated thrombotic microangiopathy - a multicentre retrospective PDWP and IEWP EBMT study2022 Bone Marrow Transplantation article Immunology and Microbiology Complement system in diseases Open access
Peter Švec, Reem Elfeky, Jacques‐Emmanuel Galimard, Christine S. Higham, Arnaud Dalissier, Troy C. Quigg, +30 more
20citations -
Lectin and alternative complement pathway activation in cutaneous manifestations of IgA-vasculitis: A new target for therapy?2022 Molecular Immunology article Immunology and Microbiology Complement system in diseases Open access
Jeffrey J. Damman, Antien L. Mooyaart, Thierry P. P. van den Bosch, Marc A. Seelen, Martijn B. van Doorn
20citations -
Risk factors for thromboembolic events in patients with paroxysmal nocturnal hemoglobinuria (PNH): a nested case–control study in the International PNH Registry2023 Annals of Hematology article Immunology and Microbiology Complement system in diseases Open access
Britta Höchsmann, Régis Peffault de Latour, Alexander Röth, Timothy Devos, Christopher Jordan Patriquin, Wen‐Chien Chou, +4 more
19citations -
Small-molecule screen reveals pathways that regulate C4 secretion in stem cell-derived astrocytes2022 Stem Cell Reports article Immunology and Microbiology Complement system in diseases Open access
Francesca A. Rapino, Ted E. Natoli, Francesco Limone, Jack Blank, Matthew Tegtmeyer, William C. Chen, +16 more
19citations -
Complement activation in secondary thrombotic microangiopathies2025 Nephrology Dialysis Transplantation article Immunology and Microbiology Complement system in diseases Open access
Johann Morelle, Fernando Caravaca‐Fontán, Fádi Fakhouri, Eleni A. Frangou, Annette N. Bruchfeld, Jürgen Floege, +9 more
18citations -
Enhancing complement activation by therapeutic anti-tumor antibodies: Mechanisms, strategies, and engineering approaches2024 Seminars in Immunology article Immunology and Microbiology Complement system in diseases Open access
Vitalijs Ovcinnikovs, Karin Dijkman, Gijs G. Zom, Frank J M Beurskens, Leendert Adrianus Trouw
18citations -
Plasma-derived and recombinant C1 esterase inhibitor: Binding profiles and neuroprotective properties in brain ischemia/reperfusion injury2021 Brain Behavior and Immunity article Immunology and Microbiology Complement system in diseases Open access
Domenico Mercurio, Arianna Piotti, Alessia Valente, Marco Oggioni, Yolanda Ponstein, Edwin V Amersfoort, +3 more
18citations -
Inhibition of complement activation by CD55 overexpression in human induced pluripotent stem cell derived kidney organoids2023 Frontiers in Immunology article Immunology and Microbiology Complement system in diseases Open access
Lonneke H. Gaykema, Rianne Y. van Nieuwland, Mette C. Dekkers, Mieke F. van Essen, Sebastiaan Heidt, Arnaud Zaldumbide, +3 more
17citations -
Medical Records-Based Genetic Studies of the Complement System2021 Journal of the American Society of Nephrology article Immunology and Microbiology Complement system in diseases Open access
Atlas Khan, Ning Shang, Lynn Petukhova, Jun Zhang, Yufeng Shen, Scott Joseph Hebbring, +15 more
16citations -
Moss-produced human complement factor H with modified glycans has an extended half-life and improved biological activity2024 Frontiers in Immunology article Immunology and Microbiology Complement system in diseases Open access cited by 2 patents
Todor Tschongov, Swagata Konwar, Andreas E Busch, Christian Sievert, Andrea Hartmann, Marina Noris, +7 more
16citations -
DNA Nanostructure-Templated Antibody Complexes Provide Insights into the Geometric Requirements of Human Complement Cascade Activation2024 Journal of the American Chemical Society article Immunology and Microbiology Complement system in diseases Open access cited by 2 patents
Leoni Abendstein, Willem E. M. Noteborn, Luc S. Veenman, Douwe J. Dijkstra, Fleur S. van de Bovenkamp, Leendert Adrianus Trouw, +1 more
16citations -
Oral iptacopan monotherapy in paroxysmal nocturnal haemoglobinuria: final 48-week results from the open-label, randomised, phase 3 APPLY-PNH trial in anti-C5-treated patients and the open-label, single-arm, phase 3 APPOINT-PNH trial in patients previously untreated with complement inhibitors2025 The Lancet Haematology article Immunology and Microbiology Complement system in diseases Open access
Antonio Maria Risitano, Austin Gladston Kulasekararaj, Phillip Scheinberg, Alexander Röth, Bing Han, Jaroslaw Pawel Maciejewski, +48 more
15citations -
Factor B Inhibition with Oral Iptacopan Monotherapy Demonstrates Sustained Long-Term Efficacy and Safety in Anti-C5-Treated Patients (pts) with Paroxysmal Nocturnal Hemoglobinuria (PNH) and Persistent Anemia: Final 48-Week Results from the Multicenter, Phase III APPLY-PNH Trial
Antonio Maria Risitano, Austin Gladston Kulasekararaj, Alexander Roeth, Phillip Scheinberg, Yutaka Ueda, Eros Di Bona, +29 more
14citations -
Development, Characterization, and in vivo Validation of a Humanized C6 Monoclonal Antibody that Inhibits the Membrane Attack Complex2022 Journal of Innate Immunity article Immunology and Microbiology Complement system in diseases Open access
Heidi Gytz Olesen, Iliana Michailidou, Wioleta Milena Zelek, Jeroen P. Vreijling, Patrick Ruizendaal, Ferry de Klein, +11 more
14citations -
Inhibition of complement factor C5a or C5aR for cholesterol crystal embolism–related vascular thrombosis with microvascular injury and its consequences2024 Kidney International article Immunology and Microbiology Complement system in diseases Open access cited by 1 patent
Chao Han, Elmina Mammadova‐Bach, Kanako Watanabe‐Kusunoki, Tâmisa Seeko Bandeira Honda, Yihong Li, Chenyu Li, +16 more
13citations
Most active Aachen authors
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Jens Panse 10,288 citations overall71 papers
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Régis Peffault de Latour 20,463 citations overall20 papers
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Leendert Adrianus Trouw 13,728 citations overall20 papers
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Antonio Maria Risitano 16,882 citations overall16 papers
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Cees van Kooten 25,919 citations overall10 papers
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Paul W.H.I. Parren 32,989 citations overall6 papers
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Haiyu Wang 1,710 citations overall6 papers
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Douwe J. Dijkstra 371 citations overall6 papers
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Leoni Abendstein 215 citations overall6 papers