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Centre for Human Drug Research
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600 stored papers ·
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Open access
Fundamentals and developments in fluorescence-guided cancer surgery
2021
Nature Reviews Clinical Oncology
review
Medicine
Optical Imaging and Spectroscopy Techniques
Open access
391
citations
The impact of lockdown on pediatric ED visits and hospital admissions during the COVID19 pandemic: a multicenter analysis and review of the literature
2021
European Journal of Pediatrics
article
Medicine
COVID-19 and healthcare impacts
Open access
214
citations
Poly(N‐isopropylacrylamide) and Its Copolymers: A Review on Recent Advances in the Areas of Sensing and Biosensing
2024
Advanced Functional Materials
article
Biochemistry, Genetics and Molecular Biology
Hydrogels: synthesis, properties, applications
Open access
147
citations
LRRK2 Inhibition by BIIB122 in Healthy Participants and Patients with Parkinson's Disease
2023
Movement Disorders
article
Medicine
Parkinson's Disease Mechanisms and Treatments
Open access
cited by 2 patents
133
citations
First-in-Human Assessment of cRGD-ZW800-1, a Zwitterionic, Integrin-Targeted, Near-Infrared Fluorescent Peptide in Colon Carcinoma
2020
Clinical Cancer Research
article
Medicine
Optical Imaging and Spectroscopy Techniques
cited by 2 patents
114
citations
Glucocerebrosidase: Functions in and Beyond the Lysosome
2020
Journal of Clinical Medicine
article
Medicine
Lysosomal Storage Disorders Research
Open access
cited by 2 patents
113
citations
Safety, pharmacokinetics and target engagement of novel RIPK1 inhibitor SAR443060 ( DNL747 ) for neurodegenerative disorders: Randomized, placebo‐controlled , double‐blind phase I/Ib studies in healthy subjects and patients
2022
Clinical and Translational Science
article
Medicine
Alzheimer's disease research and treatments
Open access
cited by 1 patent
112
citations
Indocyanine green near-infrared fluorescence bowel perfusion assessment to prevent anastomotic leakage in minimally invasive colorectal surgery (AVOID): a multicentre, randomised, controlled, phase 3 trial
2024
The Lancet. Gastroenterology & hepatology
article
Medicine
Colorectal Cancer Surgical Treatments
Open access
104
citations
Cyclic Ruthenium-Peptide Conjugates as Integrin-Targeting Phototherapeutic Prodrugs for the Treatment of Brain Tumors
2023
Journal of the American Chemical Society
article
Medicine
Metal complexes synthesis and properties
Open access
93
citations
Dose-Finding Study of a CEA-Targeting Agent, SGM-101, for Intraoperative Fluorescence Imaging of Colorectal Cancer
2020
Annals of Surgical Oncology
article
Medicine
Optical Imaging and Spectroscopy Techniques
Open access
80
citations
Fluorescence-guided surgery in colorectal cancer; A review on clinical results and future perspectives
2021
European Journal of Surgical Oncology
article
Medicine
Optical Imaging and Spectroscopy Techniques
Open access
76
citations
A Large‐Scale Full GBA1 Gene Screening in Parkinson's Disease in the Netherlands
2020
Movement Disorders
article
Medicine
Lysosomal Storage Disorders Research
Open access
cited by 2 patents
75
citations
Inflammatory plasma biomarkers in subjects with preclinical Alzheimer’s disease
2022
Alzheimer s Research & Therapy
article
Medicine
Dementia and Cognitive Impairment Research
Open access
73
citations
Licogliflozin for nonalcoholic steatohepatitis: a randomized, double-blind, placebo-controlled, phase 2a study
2022
Nature Medicine
article
Medicine
Liver Disease Diagnosis and Treatment
Open access
72
citations
Single-cell profiling reveals age-associated immunity in atherosclerosis
2023
Cardiovascular Research
article
Immunology and Microbiology
Atherosclerosis and Cardiovascular Diseases
Open access
70
citations
Current management of uveal melanoma: A review
2023
Clinical and Experimental Ophthalmology
article
Medicine
Ocular Oncology and Treatments
Open access
69
citations
Characterization of the central nervous system penetrant and selective purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder
2023
Translational Psychiatry
article
Medicine
Treatment of Major Depression
Open access
67
citations
Tolerance to Opioid‐Induced Respiratory Depression in Chronic High‐Dose Opioid Users: A Model‐Based Comparison With Opioid‐Naïve Individuals
2020
Clinical Pharmacology & Therapeutics
article
Medicine
Opioid Use Disorder Treatment
Open access
65
citations
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Crossover Study to Evaluate the Pharmacodynamic Effects of VX-150, a Highly Selective NaV1.8 Inhibitor, in Healthy Male Adults
2021
Pain Medicine
article
Medicine
Pain Mechanisms and Treatments
Open access
61
citations
Characterisation of the pharmacodynamic effects of the P2X7 receptor antagonist JNJ-54175446 using an oral dexamphetamine challenge model in healthy males in a randomised, double-blind, placebo-controlled, multiple ascending dose trial
2020
Journal of Psychopharmacology
article
Biochemistry, Genetics and Molecular Biology
Adenosine and Purinergic Signaling
61
citations
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