A Aralex Aachen research explorer

Institute RWTH Aachen University

Institute for Biomedical Technologies Sign in to save

5 authors · 20 authorships · All papers →

People 5

5 results

Papers 13

Decoding myofibroblast origins in human kidney fibrosis
2020 Nature article Medicine Chronic Kidney Disease and Diabetes Open access cited by 5 patents

801

citations
Platelet-instructed SPP1+ macrophages drive myofibroblast activation in fibrosis in a CXCL4-dependent manner
2023 Cell Reports article Medicine Cardiac Fibrosis and Remodeling Open access

336

citations
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
2021 Cell stem cell article Medicine COVID-19 Clinical Research Studies Open access cited by 1 patent

257

citations
Human pluripotent stem cell-derived kidney organoids for personalized congenital and idiopathic nephrotic syndrome modeling
2022 Development article Medicine Renal Diseases and Glomerulopathies Open access cited by 2 patents

51

citations
Enhanced fatty acid oxidation through metformin and baicalin as therapy for COVID-19 and associated inflammatory states in lung and kidney
2023 Redox Biology article Medicine COVID-19 Clinical Research Studies Open access

40

citations
ADAMTS12 promotes fibrosis by restructuring extracellular matrix to enable activation of injury-responsive fibroblasts
2024 Journal of Clinical Investigation article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access cited by 1 patent

33

citations
Human pluripotent stem cell-derived kidney organoids for personalized congenital and idiopathic nephrotic syndrome modeling
2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Renal Diseases and Glomerulopathies Open access

9

citations
Protocol to analyze bioenergetics in single human induced-pluripotent-stem-cell-derived kidney organoids using Seahorse XF96
2023 STAR Protocols article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access

3

citations
Enhanced fatty acid oxidation through Metformin and Baicalin as therapy for COVID-19 and associated inflammatory states in lung and kidney
2023 Free Radical Biology and Medicine article Biochemistry, Genetics and Molecular Biology Metabolism, Diabetes, and Cancer Open access

1

citations
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
2021 Zenodo (CERN European Organization for Nuclear Research) article Medicine SARS-CoV-2 and COVID-19 Research Open access

0

citations
SARS-CoV-2 infects kidney cells and causes kidney injury and fibrosis
2021 Zenodo (CERN European Organization for Nuclear Research) article Medicine COVID-19 Clinical Research Studies Open access

0

citations
SARS-CoV-2 infects kidney cells and causes kidney injury and fibrosis
2021 Zenodo (CERN European Organization for Nuclear Research) dataset Medicine COVID-19 Clinical Research Studies Open access

0

citations
Cyclic uremia without kidney injury drives cardiovascular disease with rapid onset of immunosenescence and heart failure
2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Dialysis and Renal Disease Management Open access

0

citations

13 results