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• ▲ Christian Preisinger

  Universitätsklinikum Aachen · RWTH Aachen University Biochemistry, Genetics and Molecular Biology
  4.04k

  citations

  30

  h-index

  33

  Aachen papers
• ▲ Mirna Barsoum

  Fraunhofer Institute for Molecular Biology and Applied Ecology · RWTH Aachen University Biochemistry, Genetics and Molecular Biology
  218

  citations

  7

  h-index

  12

  Aachen papers

2 results

• Pharmacological induction of selective endoplasmic reticulum retention as a strategy for cancer therapy

  2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Endoplasmic Reticulum Stress and Disease Open access

  69

  citations
• AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy

  2020 Nature Communications article Medicine Autophagy in Disease and Therapy Open access

  44

  citations
• The nucleoporin Nup50 activates the Ran guanine nucleotide exchange factor RCC1 to promote NPC assembly at the end of mitosis

  2021 The EMBO Journal article Biochemistry, Genetics and Molecular Biology Nuclear Structure and Function Open access

  30

  citations
• The iRhom homology domain is indispensable for ADAM17-mediated TNFα and EGF receptor ligand release

  2021 Cellular and Molecular Life Sciences article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access

  25

  citations
• A structural model of the iRhom–ADAM17 sheddase complex reveals functional insights into its trafficking and activity

  2023 Cellular and Molecular Life Sciences article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access

  18

  citations
• Targeting of BCR-ABL1 and IRE1α induces synthetic lethality in Philadelphia-positive acute lymphoblastic leukemia

  2020 Carcinogenesis article Medicine Chronic Myeloid Leukemia Treatments

  14

  citations
• TurboID-Based IRE1 Interactome Reveals Participants of the Endoplasmic Reticulum-Associated Protein Degradation Machinery in the Human Mast Cell Leukemia Cell Line HMC-1.2

  2024 Cells article Biochemistry, Genetics and Molecular Biology Endoplasmic Reticulum Stress and Disease Open access

  8

  citations
• The parkinsonism-associated protein FBXO7 cooperates with the BAG6 complex in proteasome function and controls the subcellular localization of the complex

  2021 Biochemical Journal article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access

  7

  citations
• Serum/Plasma Proteome in Non-Malignant Liver Disease

  2024 International Journal of Molecular Sciences article Chemistry Advanced Proteomics Techniques and Applications Open access

  5

  citations
• Loss of the parkinsonism‐associated protein FBXO7 in glutamatergic forebrain neurons in mice leads to abnormal motor behavior and synaptic defects

  2023 Journal of Neurochemistry article Medicine Parkinson's Disease Mechanisms and Treatments Open access

  5

  citations
• A structural model of the iRhom-ADAM17 sheddase complex reveals functional insights into its trafficking and activity

  2023 Research Square preprint Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access

  2

  citations
• 1-Phosphatidylinositol 3-Phosphate 5-Kinase Inhibition by Apilimod Promotes an Adipocyte-Like Vascular Smooth Muscle Cell Phenotype and Prevents Arterial Calcification

  2026 Circulation Research article Biochemistry, Genetics and Molecular Biology Dermatological and Skeletal Disorders

  2

  citations
• Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

  2025 Molecular Oncology article Biochemistry, Genetics and Molecular Biology Chromatin Remodeling and Cancer Open access

  2

  citations
• Dual proteotoxic stress accelerates liver injury via activation of p62‐Nrf2

  2021 The Journal of Pathology article Medicine Liver physiology and pathology Open access

  2

  citations
• The Unfolded Protein Response Mediates Resistance in AML and Its Therapeutic Targeting Enhances TKI Induced Cell Death in FLT3-ITD + AML

  2021 Blood conference-abstract Medicine Acute Myeloid Leukemia Research

  2

  citations
• The nucleoporin Nup50 activates the Ran guanyl-nucleotide exchange factor RCC1 to promote mitotic NPC assembly

  2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Nuclear Structure and Function Open access

  1

  citations

16 results