-
In Vitro Three‐Dimensional Liver Models for Nanomaterial DNA Damage Assessment2021 Small article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access
Samantha V. Llewellyn, Marije Niemeijer, Penny E. H. Nymark, Martijn J. Moné, Bob van de Water, Gillian E. Conway, +2 more
49citations -
Optimization of a pre-metabolization procedure using rat liver S9 and cell-extracted S9 in the Ames fluctuation test2020 The Science of The Total Environment article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment
Ying Shao, Andreas Schiwy, Lisa Glauch, Luise Henneberger, Maria König, Marie Mühlenbrink, +5 more
31citations -
An Adverse Outcome Pathway Network for Chemically Induced Oxidative Stress Leading to (Non)genotoxic Carcinogenesis2023 Chemical Research in Toxicology article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access
Christina H. J. Veltman, Jeroen L. A. Pennings, Bob van de Water, Mirjam Luijten
28citations -
New approach methodologies to facilitate and improve the hazard assessment of non-genotoxic carcinogens—a PARC project2023 Frontiers in Toxicology article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access
Marc Audebert, Ann-Sophie Aßmann, Amaya Azqueta, Pavel Babica, Emilio Benfenati, Sylvie Bortoli, +28 more
27citations -
Using a high-throughput method in the micronucleus assay to compare animal-free with rat-derived S92020 The Science of The Total Environment article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment
Julia Brendt, Carina Lackmann, Sebastian Heger, Mirna Velki, Sarah E. Crawford, Hongxia Xiao, +3 more
22citations -
Aneugen Versus Clastogen Evaluation and Oxidative Stress-Related Mode-of-Action Assessment of Genotoxic Compounds Using the ToxTracker Reporter Assay2020 Toxicological Sciences article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment
Inger Brandsma, Nynke Moelijker, Remco S. Derr, Giel Hendriks
22citations -
Optimization of the Ames RAMOS test allows for a reproducible high-throughput mutagenicity test2020 The Science of The Total Environment article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment
Kira Kauffmann, Alexander Deitert, Julian Finklenburg, Julia Brendt, Andreas Schiwy, Henner Hollert, +1 more
21citations -
Following the adverse outcome pathway from micronucleus to cancer using H2B-eGFP transgenic healthy stem cells2020 Archives of Toxicology article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access
Bastian Niklas Hölzel, Kurt Pfannkuche, Bernhard Allner, Hans Thomas Allner, Jürgen Hescheler, Daniel Derichsweiler, +6 more
20citations -
The influence of alkyl substitution on the in vitro metabolism and mutagenicity of benzo[a]pyrene2022 Chemico-Biological Interactions article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access
Danlei Wang, Angelique P. Groot, Albrecht Seidel, Lulu Wang, Effimia Kiachaki, Peter J. Boogaard, +1 more
20citations -
Is a liver comparable to a liver? A comparison of different rat-derived S9-fractions with a biotechnological animal-free alternative in the Ames fluctuation assay2020 The Science of The Total Environment article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment
Julia Brendt, Sarah E. Crawford, Mirna Velki, Hongxia Xiao, Beat Thalmann, Henner Hollert, +1 more
19citations -
Assessing the genotoxic potential of freshwater sediments after extensive rain events – Lessons learned from a case study in an effluent-dominated river in Germany2021 Water Research article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment
Aliaksandra Shuliakevich, Melis Muz, Jörg Oehlmann, Laura Nagengast, Katja Schröder, Yvonne Wolf, +5 more
18citations -
Combining Different In Vitro Bioassays to Evaluate Genotoxicity of Water-Accommodated Fractions from Petroleum Products2020 Toxics article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access
Sarah Johann, Mira Goßen, Peter Behnisch, Henner Hollert, Thomas‐Benjamin Seiler
18citations -
Alternative type of Ames test allows for dynamic mutagenicity detection by online monitoring of respiration activity2020 The Science of The Total Environment article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment
Kira Kauffmann, Lisa Gremm, Julia Brendt, Andreas Schiwy, Kerstin Bluhm, Henner Hollert, +1 more
16citations -
HESI GTTC ring trial: Concordance between Ames and rodent carcinogenicity outcomes for N-nitrosamines (NAs) with rat and hamster metabolic conditions2025 Regulatory Toxicology and Pharmacology article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access
Joel P. Bercu, Alejandra Trejo‐Martin, Connie L. Chen, Maik Schuler, Jennifer R. Cheung, Tetyana Cheairs, +29 more
15citations -
Selection of assay, organism, and approach in biomonitoring significantly affects the evaluation of genotoxic potential in aquatic environments2020 Environmental Science and Pollution Research article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment
Jovana Jovanović Marić, Margareta Kračun‐Kolarević, Stoimir Kolarević, Karolina Sunjog, Jovana Kostić, Björn Deutschmann, +4 more
13citations -
Transcriptomic-based evaluation of trichloroethylene glutathione and cysteine conjugates demonstrate phenotype-dependent stress responses in a panel of human in vitro models2022 Archives of Toxicology article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access
Liliana Capinha, Yaran Zhang, Anna‐Katharina Holzer, Anna‐Katharina Ückert, Melinda Zana, Giada Carta, +8 more
12citations -
Exposure to complex mixtures of urban sediments containing Tyre and Road Wear Particles (TRWPs) increases the germ-line mutation rate in Chironomus riparius2025 Aquatic Toxicology article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access
Markus Schmitz, Volker Linnemann, Martin Krayer Von Krauss, Henner Hollert, Markus Pfenninger
11citations -
Concept for the Evaluation of Carcinogenic Substances in Population-Based Human Biomonitoring2022 International Journal of Environmental Research and Public Health article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access
Klaus‐Michael Wollin, Petra Apel, Yvonni Chovolou, Ulrike Pabel, Thomas Schettgen, Marike Kolossa‐Gehring, +1 more
10citations -
Substantiate a read-across hypothesis by using transcriptome data—A case study on volatile diketones2023 Frontiers in Toxicology article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access
Matthias M. Wehr, Walter Zobl, Jeannette Koschmann, Britta Anna Kühne, Tanja Hansen, Jan Knebel, +5 more
7citations -
Advancing Genotoxicity Assessment by Building a Global AOP Network2025 Environmental and Molecular Mutagenesis article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access
Emmanuel Demuynck, Tamara Vanhaecke, Anouck Thienpont, Davie Cappoen, Freddy Van Goethem, Levi M. T. Winkelman, +12 more
6citations -
Towards an advanced testing strategy for genotoxicity using image-based 2D and 3D HepG2 DNA damage response fluorescent protein reporters2021 Mutagenesis article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access
Bas ter Braak, Marije Niemeijer, Liesanne Wolters, Sylvia E. Le Dévédec, Peter Bouwman, Bob van de Water
6citations -
EMA commentary on the ICH guideline for testing for carcinogenicity of pharmaceuticals2023 British Journal of Clinical Pharmacology article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access
Jan Willem van der Laan, Sonja Beken, Milton Bonelli, Susanne Brendler‐Schwaab, Rosemary Kane, Markku Pasanen, +5 more
5citations -
Opportunities for More Tailored Approaches to Genotoxicity Testing and Carcinogenicity Strategy for Oligonucleotide Therapeutics: Outcome of an Industry Survey2025 Nucleic Acid Therapeutics article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access
Joel D. Parry, Tod A. Harper, Patrik Urban Andersson, Joanne M. Elloway, Natalie S. Holman, William E. Achanzar, +9 more
3citations