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Hybrid Chains: A Collaboration of Ubiquitin and Ubiquitin-Like Modifiers Introducing Cross-Functionality to the Ubiquitin Code2020 Frontiers in Chemistry article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
David A. Pérez Berrocal, Katharina F. Witting, Huib Ovaa, Monique P. C. Mulder
58citations -
TRIP12 structures reveal HECT E3 formation of K29 linkages and branched ubiquitin chains2025 Nature Structural & Molecular Biology article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Samuel A. Maiwald, Ronnald Vollrath, Joanna Liwocha, Matthew D Maletic, Kirby N. Swatek, Monique P. C. Mulder, +1 more
17citations -
A modular Uba1-nanobody fusion enables selective ubiquitin transfer to tagged E2 enzymes2025 Journal of Biological Chemistry article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Charlotte Wijne, Francesca D’Amico, David A. Pérez Berrocal, Monique P. C. Mulder, Hidde L. Ploegh
1citations -
Activity-based protein profiling reveals both canonical and novel ubiquitin pathway enzymes in Plasmodium2025 PLoS Pathogens article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Cameron L. C. Smith, Mohsen Hajisadeghian, Gerbrand J. van der Heden van Noort, Michael J. Deery, Adán Pinto-Fernández, Benedikt Mathias Kessler, +1 more
2citations -
Chemogenetic ubiquitin E1 inhibitor TAK-243 CRISPR screen uncovers HAPSTR1/HUWE1 axis in chromatin proteostasis and cell cycle control2026 Science Advances article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Nila K. van Overbeek, Linda Clijsters, Martina Wirth, Ilona J. de Graaf, Klaas de Lint, Sidrit Uruci, +12 more
0citations -
Ubiquitin ligation to F-box protein targets by SCF–RBR E3–E3 super-assembly2021 Nature article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access cited by 1 patent
Daniel Horn‐Ghetko, David T. Krist, Jesuraj Rajan Prabu, Kheewoong Baek, Monique P. C. Mulder, Maren Klügel, +4 more
205citations -
Structural snapshots along K48-linked ubiquitin chain formation by the HECT E3 UBR52023 Nature Chemical Biology article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Laura A. Hehl, Daniel Horn‐Ghetko, Jesuraj Rajan Prabu, Ronnald Vollrath, Duc Tung Vu, David A. Pérez Berrocal, +3 more
74citations -
BioE3 identifies specific substrates of ubiquitin E3 ligases2023 Nature Communications article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access cited by 2 patents
Orhi Barroso‐Gomila, Laura Merino‐Cacho, Veronica Muratore, Coralia Pérez, Vincenzo Taibi, Elena Maspero, +9 more
57citations -
RNF168 E3 ligase participates in ubiquitin signaling and recruitment of SLX4 during DNA crosslink repair2021 Cell Reports article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Yoko Katsuki, Masako Abe, Seon Young Park, Wenwen Wu, Hiromasa Yabe, Miharu Yabe, +6 more
13citations -
Deciphering non-canonical ubiquitin signaling: biology and methodology2024 Frontiers in Molecular Biosciences article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Nila K. van Overbeek, Tim Aguirre, Gerbrand J. van der Heden van Noort, Blagoy Blagoev, Alfred C.O. Vertegaal
11citations -
Strategy for Development of Site-Specific Ubiquitin Antibodies2020 Frontiers in Chemistry article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Ila van Kruijsbergen, Monique P. C. Mulder, Michael Uckelmann, Tibor van Welsem, John de Widt, Aldo Spanjaard, +4 more
12citations -
Inhibiting UCH-L5: Rational Design of a Cyclic Ubiquitin-Based Peptide Inhibitor2022 Frontiers in Molecular Biosciences article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Dharjath S. Hameed, Huib Ovaa, Gerbrand J. van der Heden van Noort, Ayşegül Sapmaz
2citations -
A functional screen for bacterial ubiquitin regulation identifies an unusual Pseudomonas aeruginosa E3 ligase2026 The EMBO Journal article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Cameron G. Roberts, Supender Kaur, Shun‐Je Bhark, Aaron J. Ogden, Michael E. Divine, Gus D. Warren, +9 more
0citations -
Specificity and recognition of the ADP-ribosyl-ubiquitin modification in the DNA damage response2026 PLoS Biology article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Chatrin Chatrin, Kang Zhu, Michael D. R. Simmons, Lucy Maginn, Kira Schützenhofer, Yang Lu, +9 more
0citations -
Selective USP32 inhibition reveals endosomal ubiquitin signaling and enables cell-permeable activity-based probes2026 Cell chemical biology article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Stephan Scherpe, Febe C. Vermue, Vito Pol, Raymond Kooij, Adán Pinto-Fernández, Rayman T.N. Tjokrodirijo, +8 more
0citations -
A Pro‐Fluorescent Ubiquitin‐Based Probe to Monitor Cysteine‐Based E3 Ligase Activity2023 Angewandte Chemie International Edition article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
David A. Pérez Berrocal, Thimmalapura M. Vishwanatha, Daniel Horn‐Ghetko, J. Josephine Botsch, Laura A. Hehl, Sebastian Kostrhon, +6 more
4citations -
A Pro‐Fluorescent Ubiquitin‐Based Probe to Monitor Cysteine‐Based E3 Ligase Activity2023 Angewandte Chemie article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
David A. Pérez Berrocal, Thimmalapura M. Vishwanatha, Daniel Horn‐Ghetko, J. Josephine Botsch, Laura A. Hehl, Sebastian Kostrhon, +6 more
0citations