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Hybrid Chains: A Collaboration of Ubiquitin and Ubiquitin-Like Modifiers Introducing Cross-Functionality to the Ubiquitin Code2020 Frontiers in Chemistry article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
David A. Pérez Berrocal, Katharina F. Witting, Huib Ovaa, Monique P. C. Mulder
58citations -
Structural snapshots along K48-linked ubiquitin chain formation by the HECT E3 UBR52023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Laura A. Hehl, Daniel Horn‐Ghetko, Jesuraj Rajan Prabu, Ronnald Vollrath, Duc Tung Vu, David A. Pérez Berrocal, +3 more
11citations -
TRIP12 structures reveal HECT E3 formation of K29 linkages and branched ubiquitin chains2025 Nature Structural & Molecular Biology article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Samuel A. Maiwald, Ronnald Vollrath, Joanna Liwocha, Matthew D Maletic, Kirby N. Swatek, Monique P. C. Mulder, +1 more
17citations -
Mechanism of Lys6 poly-ubiquitin specificity by the L. pneumophila deubiquitinase LotA2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Gus D. Warren, Tomoe Kitao, Tyler G. Franklin, Justine V. Nguyen, Paul P. Geurink, Tomoko Kubori, +2 more
2citations -
A functional screen for ubiquitin regulation identifies an E3 ligase secreted by Pseudomonas aeruginosa2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Cameron G. Roberts, Supender Kaur, Aaron J. Ogden, Michael E. Divine, Gus D. Warren, Donghoon Kang, +8 more
2citations -
A modular Uba1-nanobody fusion enables selective ubiquitin transfer to tagged E2 enzymes2025 Journal of Biological Chemistry article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Charlotte Wijne, Francesca D’Amico, David A. Pérez Berrocal, Monique P. C. Mulder, Hidde L. Ploegh
1citations -
Activity-based protein profiling reveals both canonical and novel ubiquitin pathway enzymes in Plasmodium2025 PLoS Pathogens article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Cameron L. C. Smith, Mohsen Hajisadeghian, Gerbrand J. van der Heden van Noort, Michael J. Deery, Adán Pinto-Fernández, Benedikt Mathias Kessler, +1 more
2citations -
Identification of a new Plasmodium falciparum E2 ubiquitin conjugating enzyme2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Cameron L. C. Smith, Mohsen Hajisadeghian, Gerbrand J. van der Heden van Noort, Adán Pinto-Fernández, Benedikt Mathias Kessler, Katerina Artavanis‐Tsakonas
0citations -
Chemogenetic ubiquitin E1 inhibitor TAK-243 CRISPR screen uncovers HAPSTR1/HUWE1 axis in chromatin proteostasis and cell cycle control2026 Science Advances article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Nila K. van Overbeek, Linda Clijsters, Martina Wirth, Ilona J. de Graaf, Klaas de Lint, Sidrit Uruci, +12 more
0citations -
Ubiquitin ligation to F-box protein targets by SCF–RBR E3–E3 super-assembly2021 Nature article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access cited by 1 patent
Daniel Horn‐Ghetko, David T. Krist, Jesuraj Rajan Prabu, Kheewoong Baek, Monique P. C. Mulder, Maren Klügel, +4 more
205citations -
Survey of the human proteostasis network: the ubiquitin-proteasome system2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Suzanne Elsasser, Evan T. Powers, Thomas Stoeger, Xiaojing Sui, Roy Kurtzbard, Patricia Martínez-Botía, +14 more
6citations -
Proximity interaction analysis of the Plasmodium falciparum putative ubiquitin ligase Pf RNF1 reveals a role in RNA regulation2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Malaria Research and Control Open access
Afia Farrukh, Jean Pierre Musabyimana, Ute Distler, Stefan Tenzer, Gabriele Pradel, Che Julius Ngwa
0citations -
Structural snapshots along K48-linked ubiquitin chain formation by the HECT E3 UBR52023 Nature Chemical Biology article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Laura A. Hehl, Daniel Horn‐Ghetko, Jesuraj Rajan Prabu, Ronnald Vollrath, Duc Tung Vu, David A. Pérez Berrocal, +3 more
74citations -
Drug resistance-associated mutations in Plasmodium UBP-1 disrupt ubiquitin hydrolysis2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Malaria Research and Control Open access
Ryan C. Henrici, Maryia Karpiyevich, Megan R. Ansbro, Johanna Hoshizaki, Gerbrand J. van der Heden van Noort, David Benjamin Ascher, +3 more
0citations -
BioE3 identifies specific substrates of ubiquitin E3 ligases2023 Nature Communications article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access cited by 2 patents
Orhi Barroso‐Gomila, Laura Merino‐Cacho, Veronica Muratore, Coralia Pérez, Vincenzo Taibi, Elena Maspero, +9 more
57citations -
RNF168 E3 ligase participates in ubiquitin signaling and recruitment of SLX4 during DNA crosslink repair2021 Cell Reports article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Yoko Katsuki, Masako Abe, Seon Young Park, Wenwen Wu, Hiromasa Yabe, Miharu Yabe, +6 more
13citations