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Identification of a novel pyroptosis related long noncoding RNA subtypes, development of a prognostic model and characteristics of the tumor microenvironment in gastric cancer0citations
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Bulk RNA sequencing deconvolution of pancreatic ductal adenocarcinoma identifies cancer-associated fibroblast subsets associated with survival and tumor microenvironment composition2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Pancreatic and Hepatic Oncology Research Open access
Nicole Dam, Mischa Steketee, Gaby J. Strijk, Willem de Koning, Lukas J.A.C. Hawinkels, Vera Kemp, +2 more
0citations -
Methylation-Guided Stratification of Colorectal Cancer Reveals Immune Subtypes with Distinct Clinical Outcomes2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation
Eiman I. Ahmed, Raghvendra Mall, Christophe Michel Raynaud, Heba Saadeh, Shimaa Sherif, Rania Alanany, +4 more
0citations -
Spatial Structure of Tumor and Immune Cells Shape Outcomes in ER⁺HER2⁻ and Triple-Negative Breast Cancer2025 medRxiv preprint Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access
Iris Nederlof, Siamak Hajizadeh, Rolf Harkes, Barbara Andrade Barbosa, Michiel de Maaker, Ingrid Hofland, +19 more
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Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity and cancer-emergent oncogenic drivers2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cancer-related molecular mechanisms research Open access
Jeffrey Wang, Jung Min Suh, Brian J Woo, Albertas Navickas, Kristle Garcia, Keyi Yin, +10 more
7citations -
Multiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Glioma Diagnosis and Treatment Open access
Hannah Voß, Shweta Godbole, Simon Schlumbohm, Yannis Schumann, Martin Mynarek, Stefan Rutkowski, +14 more
1citations -
The Impact of Digital Histopathology Batch Effect on Deep Learning Model Accuracy and Bias2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Computer Science AI in cancer detection Open access
Frederick Matthew Howard, James M. Dolezal, Sara E. Kochanny, Jefree J. Schulte, Heather Chen, Lara Rosaline Heij, +7 more
25citations -
Pan-Cancer landscape of protein activities identifies drivers of signalling dysregulation and patient survival2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cancer Genomics and Diagnostics Open access
Abel Sousa, Aurélien J. F. Dugourd, Danish Memon, Borgþór Pétursson, Evangelia Petsalaki, Julio Sáez-Rodríguez, +1 more
6citations -
SPAG6 promotes cell migration and induces epithelial-to-mesenchymal transition in luminal breast cancer cells2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access
Jolein Mijnes, Sarah Bringezu, Carmen Schalla, Michael Rose, Sonja von Serényi, Ruth Knüchel‐Clarke, +2 more
4citations -
Machine learning approach identifies miRNA signatures for breast cancer detection and classification from patient urine samples2024 Research Square preprint Biochemistry, Genetics and Molecular Biology MicroRNA in disease regulation Open access
Jochen Maurer, Matthias Rübner, Chao‐Chung Kuo, Birgit Klein, Julia Franzen, Julia Wittenborn, +4 more
1citations -
DEEP LEARNING APPROACH FOR RENAL CELL CARCINOMA DETECTION, SUBTYPING, AND GRADING2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Computer Science AI in cancer detection Open access
Maroof Abdul Aziz, Fatemeh Javadian, Sherin Susheel Mathew, Gopal Avinash, Johannes Stegmaier, Abin Jose
0citations -
Spatially-resolved tumour infiltrating immune cells and prognosis in breast cancer2024 medRxiv preprint Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access
Aaron J. Bernstein, Renske Keeman, Amber N. Hurson, Fiona M. Blows, Manjeet K. Bolla, Jodi L. Miller, +57 more
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Inter-Spheroid Proximity and Matrix Remodeling Determine CAF-Mediated Cancer Cell Invasion2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions Open access
Pranav Mehta, Ankur Bordoloi, Cor J. Ravensbergen, M. Kristen David, Wilma E. Mesker, Gerrit‐Jan Liefers, +2 more
1citations -
TIGIT drives the immunosuppressive environment by downregulation of metalloproteinases MMP2 and MMP14 in perihilar cholangiocarcinoma2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cholangiocarcinoma and Gallbladder Cancer Studies Open access
Lara Rosaline Heij, Konrad Reichel, Willem de Koning, Jan Bednarsch, Xiuxiang Tan, Julia Campello Deierl, +13 more
0citations -
TGFβ signaling in cancer-associated fibroblasts drives a hepatic gp130-dependent pro-metastatic inflammatory program in CMS4 colorectal cancer subtype2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Tom J. Harryvan, Subinuer Abudukelimu, Imke Stouten, EJ van der Wel, Kristiaan Lenos, OJ Sansom, +1 more
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Integrating cell interaction with transcript factors to obtain a robust gene panel for prognostic prediction and therapies in cholangiocarcinoma2022 Research Square preprint Medicine Cholangiocarcinoma and Gallbladder Cancer Studies Open access
Tingjie Wang, Chuanrui Xu, Dan Xu, Xiaofei Yang, Yaxin Liu, Xiujuan Li, +4 more
0citations