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An international, multicentre, interventional, randomised, assessor-blinded trial to MAXimise the METHotrexate therapy potential in patients with active rheumatoid arthritis (MethMax trial): study protocol for a randomised controlled trial
Karolina Anderle, Daniela Sieghart, Martina Durechova, François Bonnay, Andreas Kerschbaumer, Katerina Chatzidionysiou, +13 more
0citations -
Accelerating vaccine trial conduct in a pandemic with a hot spot‐based inclusion strategy using trial and epidemic simulation2021 Clinical and Translational Science article Mathematics Statistical Methods in Clinical Trials Open access
Johan L. van der Plas, Michiel Joost van Esdonk, Ingrid M. C. Kamerling, Adam F. Cohen
7citations -
Ensuring Transparency and Quality of Clinical Trial Reporting in Clinical Pharmacology & Therapeutics: Prospective Trial Registration and Compliance with Reporting Guidelines Are Required for all Clinical Trials2023 Clinical Pharmacology & Therapeutics article Decision Sciences Meta-analysis and systematic reviews Open access
D. Max Smith, Iris K. Minichmayr, Joseph Frank Standing, Kathleen M. Giacomini, Piet H. van der Graaf, Richard Peck
2citations -
Updated protocol of the SANO trial: a stepped-wedge cluster randomised trial comparing surgery with active surveillance after neoadjuvant chemoradiotherapy for oesophageal cancer
Ben M. Eyck, Berend J. van der Wilk, Bo Jan Noordman, Bas P. L. Wijnhoven, Sjoerd M. Lagarde, Henk H. Hartgrink, +18 more
94citations -
Care after pancreatic resection according to an algorithm for early detection and minimally invasive management of pancreatic fistula versus current practice (PORSCH-trial): design and rationale of a nationwide stepped-wedge cluster randomized trial
F. Jasmijn Smits, AC Henry, CH van Eijck, Marc G. Besselink, O. R. C. Busch, M Arntz, +25 more
0citations -
Economic evaluation of endometrial scratching before the second IVF/ICSI treatment: a cost-effectiveness analysis of a randomized controlled trial (SCRaTCH trial)
Nienke E. van Hoogenhuijze, Rik van EEKELEN, Femke Mol, Inger Birgitta Schipper, Eva R. Groenewoud, Maaike A. F. Traas, +31 more
17citations -
Pain and Opioid Consumption After Laparoscopic Versus Open Gastrectomy for Gastric Cancer: A Secondary Analysis of a Multicenter Randomized Clinical Trial (LOGICA-Trial)2023 Journal of Gastrointestinal Surgery article Medicine Anesthesia and Pain Management Open access
Arjen van der Veen, Mark Ramaekers, Marije Marsman, Hylke J.F. Brenkman, Maarten F. J. Seesing, Misha D. P. Luyer, +27 more
6citations -
Representativeness of trial participants: linking the EORTC boost-no boost trial to the Netherlands cancer registry2022 Journal of Clinical Epidemiology article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access
Anouk Neven, Marissa Corine van Maaren, Kay Schreuder, Ries Kranse, Henk Struikmans, Philip M. Poortmans, +4 more
0citations -
The death of a neurotrauma trial lessons learned from the prematurely halted randomized evaluation of surgery in elderly with traumatic acute subdural hematoma (RESET-ASDH) trial
Ranjit D. Singh, Jeroen T.J.M. van Dijck, Thomas Arjan van Essen, Hayden P. Nix, Rick Vreeburg, Hugo F. den Boogert, +3 more
6citations -
Design and rationale of the prospective, randomized, controlled trial to assess the management of moderate aortic stenosis by clinical surveillance or transcatheter aortic valve replacement: The PROGRESS Trial
Philippe Généreux, Raj Makkar, Jeroen Joost Bax, Philippe Pîbarot, Brian R. Lindman, Brandon Park, +3 more
3citations -
Levothyroxine in euthyroid thyroid peroxidase antibody positive women with recurrent pregnancy loss (T4LIFE trial): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial2022 The Lancet Diabetes & Endocrinology article Medicine Thyroid Disorders and Treatments Open access
Marie‐Louise van der Hoorn, Ole Bjarne Christiansen, Madelon van Wely
95citations -
Adjuvant hepatic arterial infusion pump chemotherapy with floxuridine for patients with resectable colorectal liver metastases and a low clinical risk score: A randomized controlled trial—The PUMP trial.2026 Journal of Clinical Oncology conference-abstract Medicine Colorectal Cancer Treatments and Studies
Loubna Outmani, Florian Buisman, Wills F. Filipe, Karen Bolhuis, Leni van Doorn, Pascal Gabriël Doornebosch, +14 more
3citations -
Randomized controlled trial of an internet-based self-guided hand exercise program to improve hand function in people with systemic sclerosis: the Scleroderma Patient-centered Intervention Network Hand Exercise Program (SPIN-HAND) trial
Linda Kwakkenbos, Marie‐Eve Carrier, Joep Welling, Brooke Levis, A.H. Levis, Maureen Sauvé, +89 more
15citations -
The ENSURE trial for women with low-risk, early-stage endometrial cancer: A randomized controlled trial comparing the effect of a reduced (4 visits/3 yr) versus usual (8-11 visits/3 yr) follow-up schedule on patient satisfaction, health care use, and disease perception.2022 Journal of Clinical Oncology conference-abstract Medicine Endometrial and Cervical Cancer Treatments
Lonneke Veronique van de Poll-Franse, Belle Hadewijch de Rooij, Carien L. Creutzberg, Roy F.P.M. Kruitwagen, Luc R.C.W. van Lonkhuijzen, Mirjam J. A. Apperloo, +5 more
0citations -
Total neoadjuvant FOLFIRINOX versus neoadjuvant gemcitabine-based chemoradiotherapy and adjuvant gemcitabine for resectable and borderline resectable pancreatic cancer (PREOPANC-2 trial): study protocol for a nationwide multicenter randomized controlled trial
Quisette P. Janssen, Jacob L. van Dam, Bert A. Bonsing, Koop P Bosscha, P. P. L. O. Coene, Casper H.J. van Eijck, +14 more
168citations -
Pragmatic randomised controlled trial of very early etanercept and MTX versus MTX with delayed etanercept in RA: the VEDERA trial2020 Annals of the Rheumatic Diseases article Medicine Rheumatoid Arthritis Research and Therapies Open access
Paul E. Emery, Sarah Horton, Raluca Bianca Dumitru, Kamran Naraghi, Désirée M F M van der Heijde, Richard J. Wakefield, +2 more
32citations -
How effective is topical miconazole or amorolfine for mild to moderately severe onychomycosis in primary care: the Onycho Trial – a randomised double-blind placebo-controlled trial
Roeland M. Watjer, Tobias Nicolaas Bonten, Khisraw Sayed, Koen D. Quint, Martha T. van der Beek, Bart J.A. Mertens, +2 more
1citations -
Assessing the efficacy and safety of mycophenolate mofetil versus azathioprine in patients with autoimmune hepatitis (CAMARO trial): study protocol for a randomised controlled trial
Romée J.A.L.M. Snijders, Anna Stoelinga, Tom J.G. Gevers, Simon Pape, Maaike Biewenga, Robert C. Verdonk, +20 more
12citations -
The impact of deep versus standard neuromuscular block on intraoperative safety during laparoscopic surgery: an international multicenter randomized controlled double-blind strategy trial — EURO-RELAX TRIAL
Gabby T. J. A. Reijnders‐Boerboom, Salome Dell‐Kuster, Monique van Velzen, Chris H. Martini, Franco Valenza, Paolo L. Proto, +8 more
7citations -
Study protocol for the DISTINCT trial: inDividual, targeted thrombosIS prophylaxis versus the standard ‘one-size-fits-all’ approach in patients undergoing Total hIp or total kNee replaCemenT – a national, multicentre, randomised, multiarm, open-label trial
Ruben Y Kok, Leti van Bodegom‐Vos, Harmen B. Ettema, Rolf H. H. Groenwold, Wilbert B. van den Hout, Menno V. Huisman, +8 more
0citations -
Care after pancreatic resection according to an algorithm for early detection and minimally invasive management of pancreatic fistula versus current practice (PORSCH-trial): design and rationale of a nationwide stepped-wedge cluster-randomized trial
F. Jasmijn Smits, Anne Claire Henry, Casper H.J. van Eijck, Marc G. Besselink, Olivier R. Busch, Mark J. Arntz, +25 more
45citations