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The NLRP1 inflammasome emerges as a promising therapeutic target and prognostic biomarker across multiple cancer types: A comprehensive pan-cancer analysis2024 Research Square preprint Biochemistry, Genetics and Molecular Biology Inflammasome and immune disorders Open access
Leila Habibipour, Mahboubeh Sadeghi, Alireza Raghibi, Amirhossein Mohajeri Khorasani, Pegah Mousavi, Nima Sanadgol
0citations -
High Density Lipoprotein pathway as a therapeutic target for coronary heart disease: individual participant meta-analysis in 28,597 individuals with 4197 coronary events
Amy R. Mulick, David Prieto‐Merino, Therese Tillin, Aki Samuli Havulinna, Martin J. Shipley, Desirée Valera‐Gran, +17 more
4citations -
Deconvolution of cellular subsets in human tissue based on targeted DNA methylation analysis at individual CpG sites2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access
Marco F. Schmidt, Tiago Maié, Edgar Dahl, Ivan G. Costa, Wolfgang Wagner
2citations -
Implicating genes, pleiotropy and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis2021 medRxiv preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Stavroula Kanoni, Sarah E. Graham, Yuxuan Wang, Ida L. Surakka, Shweta Ramdas, Xiang Zhu, +91 more
8citations -
Analysis of pre-symptomatic Drosophila models for ALS and SMA reveals convergent impact on functional protein complexes linked to neuro-muscular degeneration2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Amyotrophic Lateral Sclerosis Research Open access
Marina L. García‐Vaquero, Barbara Flix, Marcelo Henrique Neves Pereira, Lucile Palin, Tânia Monteiro Marques, Francisco Rodrigues Pinto, +4 more
0citations -
Comparative phosphoproteome analysis of primary and metastatic uveal melanoma cell lines2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Ocular Oncology and Treatments Open access
Kseniya Glinkina, Román González‐Prieto, Amina F.A.S. Teunisse, Maria Chiara Gelmi, Martine Johanna Jager, Alfred C.O. Vertegaal, +1 more
0citations -
The Drug Rediscovery Protocol (DRUP trial): A Dutch National Study on behalf of the Center for Personalized Cancer Treatment (CPCT) to Facilitate Patient Access to Commercially Available, Targeted Anti-cancer Drugs to determine the Potential Efficacy in Treatment of Advanced Cancers with a Known Molecular Profile2020 Research Square preprint Biochemistry, Genetics and Molecular Biology Cancer Genomics and Diagnostics Open access
Emile E. Voest, Henk M.W. Verheul, Hans A. J. Gelderblom, Daphne L. van der Velden, Louisa Rose Hoes, Hanneke van der Wijngaart, +1 more
1citations -
MUSICiAn: Genome-wide Identification of Genes Involved in DNA Repair via Control-Free Mutational Spectra Analysis2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Colm Seale, Marco Barazas, Robin van Schendel, Marcel Tijsterman, Joana P. Gonçalves
3citations -
Toward navigating emotional states using real-time representational similarity analysis fMRI neurofeedback - a feasibility study2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience EEG and Brain-Computer Interfaces Open access
Assunta Ciarlo, Michael Lührs, Alexander Atanasyan, David Böken, Jürgen Roßmann, Michael Schluse, +7 more
0citations -
Searchlight Optimization Using Representational Similarity Analysis for Subject-Level Voxel Selection in Emotional State Decoding2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Functional Brain Connectivity Studies Open access
Xuelei Wang, Jana Zweerings, Michael Lührs, Fengyu Cong, Klaus Mathiak, David E.J. Linden, +3 more
0citations -
Structure-function analysis of the nsp14 N7-guanine methyltransferase reveals an essential role in Betacoronavirus replication2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine SARS-CoV-2 and COVID-19 Research Open access
Natacha S. Ogando, Priscila El Kazzi, Jessika C. Zevenhoven-Dobbe, Brenda W. Bontes, Alice Decombe, Clara C. Posthuma, +5 more
0citations -
Bayesian multi-model-based 13 C 15 N-metabolic flux analysis quantifies carbon-nitrogen metabolism in mycobacteria2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Khushboo Borah, Martin Beyß, Ye Xu, Jim Barber, Catia Costa, Jane Newcombe, +5 more
3citations -
PHLOWER - Single cell trajectory analysis using Hodge Decomposition2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Mingbo Cheng, Jitske Jansen, Katharina C. Reimer, James Shiniti Nagai, Zhijian Li, Paul Kießling, +5 more
0citations -
Higher Versus Lower Oxygenation Strategies in The General Intensive Care Unit Population: A Systematic Review, Meta-Analysis and Meta-Regression of Randomized Controlled Trials.
Lea Imeen van der Wal, Chloe C.A. Grim, David J. van Westerloo, M.J. Schultz, Evert de Jonge, Hendrik J. F. Helmerhorst
1citations -
Population genomic analysis reveals cryptic population structure in the commercially important Lake Malawi cichlid Copadichromis mloto2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genetic diversity and population structure Open access
Wilson Sawasawa, Alexander Hooft van Huysduynen, Sophie Gresham, Harold Sungani, Bosco Rusuwa, Gudrun De Boeck, +3 more
1citations -
Structural and functional analysis of the Mycobacterium tuberculosis MmpS5L5 efflux pump presages a pathway to increased bedaquiline resistance2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Tuberculosis Research and Epidemiology Open access
Adam J. Fountain, Jan Böhning, Stephen H. McLaughlin, Tomos E. Morgan, Paul H. Edelstein, Mark A. Troll, +4 more
4citations