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Adverse effects of delayed antimicrobial treatment and surgical source control in adults with sepsis: results of a planned secondary analysis of a cluster-randomized controlled trial
Hendrik Rüddel, Daniel O. Thomas-Rüddel, Konrad Reinhart, Friedhelm Bach, Herwig Gerlach, Matthias Lindner, +81 more
75citations -
S3-Leitlinie Sepsis – Prävention, Diagnose, Therapie und Nachsorge – Update 20252025 Medizinische Klinik - Intensivmedizin und Notfallmedizin article Medicine Sepsis Diagnosis and Treatment Open access
Frank Martin Brunkhorst, Michael Adamzik, Hubertus Axer, Michael W Bauer, Christian Bode, Hans-Georg Bone, +44 more
26citations -
Elevated Serum KIM-1 in Sepsis Correlates with Kidney Dysfunction and the Severity of Multi-Organ Critical Illness2024 International Journal of Molecular Sciences article Medicine Acute Kidney Injury Research Open access
Jonathan Frederik Brozat, Neval Harbalioğlu, Philipp Hohlstein, Samira Abu Jhaisha, Maike R. Pollmanns, Jule K. Adams, +7 more
17citations -
Depletion of Neonatal Neutrophilic Cells Worsens the Outcome of E. coli Sepsis in Newborn Mice2026 European Journal of Immunology article Immunology and Microbiology Neutrophil, Myeloperoxidase and Oxidative Mechanisms Open access
Julian Schwarz, Janine Hebel, Stefanie Dietz‐Ziegler, Jessica Rühle, Trim Lajqi, Thorsten W Orlikowsky, +3 more
0citations -
Enterobacter cloacae as a Rare Cause of Cerebral Abscesses in a Neonatal Late-Onset Sepsis—a Case Report and Literature Review with Focus on Risk Factors, Diagnostics, and Treatment2024 Journal of Pediatric Infectious Diseases article Biochemistry, Genetics and Molecular Biology Enterobacteriaceae and Cronobacter Research
Yildiz Yildirim, Ruy Perez, Rüdiger Wentzell, Clemens Andrée, Martin Weinzierl, Norbert Utz, +1 more
0citations -
Soluble Neuropilin-1 Is Elevated in Sepsis and Correlates with Organ Dysfunction and Long-Term Mortality in Critical Illness2024 International Journal of Molecular Sciences article Medicine Sepsis Diagnosis and Treatment Open access
Philipp Hohlstein, Eileen Schumacher, Samira Abu Jhaisha, Jule K. Adams, Maike R. Pollmanns, Carolin Victoria Schneider, +7 more
3citations -
The 24-Hour Leukocyte Gap as a novel predictor for sepsis in adult severe blunt trauma2025 Langenbeck s Archives of Surgery article Immunology and Microbiology Immune Response and Inflammation Open access
Michel Paul Johan Teuben, Alba Shehu, Ester Mikova, Rald V. M. Groven, Felix Karl-Ludwig Klingebiel, Roman Pfeifer, +1 more
0citations -
Differential Gene Expression in Circulating CD14+ Monocytes Indicates the Prognosis of Critically Ill Patients with Sepsis2020 Journal of Clinical Medicine article Immunology and Microbiology Immune cells in cancer Open access
Anke Liepelt, Philipp Hohlstein, Hendrik Gussen, Anna C. Aschenbrenner, Thomas Ulas, Lukas Buendgens, +7 more
34citations -
Endoplasmic reticulum stress and the unfolded protein response in skeletal muscle of subjects suffering from peritoneal sepsis: Data from a cross-sectional and experimental study
Christian von Loeffelholz, René Winkler, Falk Rauchfuß, UB Metzing, Utz Settmacher, Christian Stoppe, +5 more
0citations -
Effects of a clinical metagenomics intervention on clinical outcomes, healthcare costs, and health-related quality of life in patients with sepsis or septic shock: results of the randomized-controlled DigiSep trial
Thorsten Brenner, Annabell Skarabis, Stefan Josef Schaller, Thilo von Groote, Christian Putensen, Ulf Günther, +45 more
3citations