Papers matching “phenotypic drug discovery” 52
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In vitro Three-Dimensional Sprouting Assay of Angiogenesis using Mouse Embryonic Stem Cells for Vascular Disease Modeling and Drug Testing2021 Journal of Visualized Experiments article Biochemistry, Genetics and Molecular Biology Angiogenesis and VEGF in Cancer cited by 2 patents
Georgios Galaris, Jérémy H. Thalgott, Eliott Teston, Franck Lebrin
4citations -
Impedance-Based Phenotypic Readout of Transporter Function: A Case for Glutamate Transporters2022 Frontiers in Pharmacology article Biochemistry, Genetics and Molecular Biology Amino Acid Enzymes and Metabolism Open access
Hubert J. Sijben, Laura Dall’ Acqua, Rongfang Liu, Eirini Christodoulaki, Svenja Onstein, Gernot Wolf, +6 more
9citations -
Data and code supporting: From Phenotypic Screening to Target and Compound Prioritization for Autosomal Dominant Polycystic Kidney Disease2026 Zenodo (CERN European Organization for Nuclear Research) dataset Computer Science Computational Drug Discovery Methods Open access
David Alencar Araripe, Margarita Iljin, Hester Bange, Leo Price, Rongfang Liu, Daan van der Es, +3 more
0citations -
Data and code supporting: From Phenotypic Screening to Target and Compound Prioritization for Autosomal Dominant Polycystic Kidney Disease2026 Zenodo (CERN European Organization for Nuclear Research) dataset Computer Science Computational Drug Discovery Methods Open access
David Alencar Araripe, Margarita Iljin, Hester Bange, Leo Price, Rongfang Liu, Daan van der Es, +3 more
0citations -
White Paper: Mimetics of Class 2 Tumor Suppressor Proteins as Novel Drug Candidates for Personalized Cancer Therapy2022 Cancers article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access
Edgar Dahl, Sophia Villwock, Peter Habenberger, Axel Choidas, Michael Rose, Bert Klebl
17citations -
Systematic assessment of transcriptomic and phenotypic biological profiling for mechanism-based hazard assessment using target-annotated reference chemicals in renal proximal tubular epithelial cells2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Computer Science Computational Drug Discovery Methods Open access
Hugo W van Kessel, Marlene Wedler, Palle Steen Helmke, Dace Zigure, Stephen Ferguson, Joshua Harrill, +5 more
0citations -
A phenotype-driven data and drug repurposing strategy used to identify potential treatments targeting chondrocyte hypertrophy in osteoarthritis2025 Biomedicine & Pharmacotherapy article Medicine Osteoarthritis Treatment and Mechanisms Open access
Judith Veldman, Mauricio N. Ferrao Blanco, Nicole Kops, Wendy J. L. M. Koevoet, Eric M. Bindels, Gregory van Beek, +5 more
0citations -
INNV-35. Artificial intelligence in Neuro-Oncology: Mapping the field2025 Neuro-Oncology article Medicine Artificial Intelligence in Healthcare and Education Open access
Sebastian Voigtlaender, Thomas Allen Nelson, Philipp Karschnia, Eugene Vaios, Michelle M. Kim, Philipp Lohmann, +7 more
0citations -
A High Content Imaging and Machine Learning Approach to Identify the Anti-Cancer Effect of Novel Small Molecules on Brain Cancer Patient-Derived Organoids2025 Microscopy and Microanalysis article Biochemistry, Genetics and Molecular Biology Cell Image Analysis Techniques Open access
Rizwan Ali, Yassinali Tamboli, Saba M. Alsubaie, Sikander Hayat, Mohamed Boudjelal
0citations -
Cryopreservation of human adult ventricular tissue for the preparation of viable myocardial slices2024 Cardiovascular Research article Medicine Tissue Engineering and Regenerative Medicine Open access
Alessandra Maria Lodrini, Azra Husetić, Boudewijn P. T. Kruithof, Jesper Hjortnaes, Meindert Palmen, Anke M. Smits, +1 more
0citations -
Addition of trans fat and alcohol has divergent effects on atherogenic diet-induced liver injury in rodent models of steatohepatitis2020 American Journal of Physiology-Gastrointestinal and Liver Physiology article Medicine Liver Disease Diagnosis and Treatment Open access
Samuel Joseph Daniels, Diana Julie Leeming, Sönke Detlefsen, Maria Fuglsang Bruun, Sara Toftegaard Hjuler, Kim Henriksen, +6 more
5citations -
Modeling Hepatocellular Carcinoma and its microenvironment on a chip Hepatocellular carcinoma PDChip2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Engineering 3D Printing in Biomedical Research Open access
Orsola Mocellin, Stéphane Treillard, Abbie Robinson, Aleksandra Olczyk, Thomas Olivier, Chee Ping Ng, +9 more
1citations -
Nintedanib Targets KIT D816V Neoplastic Cells Derived from Induced Pluripotent Stem cells of Systemic Mastocytosis2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Mast cells and histamine Open access
Marcelo A. S. Toledo, Malrun Gatz, Stephanie Sontag, Karoline Veronika Gleixner, Gregor Eisenwort, Kristina Feldberg, +21 more
4citations