Papers matching “pharmacodynamic evaluation” 13
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Fixed dosing of tocilizumab in ICU admitted COVID-19 patients is a superior choice compared to bodyweight based dosing; an observational population pharmacokinetic and pharmacodynamic study
Dirk Jan A. R. Moes, David J. van Westerloo, Sandra M. Arend, Jesse Joachim Swen, Annick de Vries, Henk‐Jan Guchelaar, +4 more
3citations -
Divergent spontaneous antibiotic-resistance evolution confers reciprocal and exploitable collateral sensitivity effects2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Antibiotic Resistance in Bacteria Open access
Apostolos Liakopoulos, Sebastian Tommi Tandar, Irene V Hoogendijk, Efthymia Fragkiskou, Zheren Zhang, Bastienne Vriesendorp, +3 more
0citations -
Quantitative Systems Pharmacology Modeling Framework of Autophagy in Tuberculosis: Application to Adjunctive Metformin Host-Directed Therapy2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Tuberculosis Research and Epidemiology Open access
Krina Mehta, Tingjie Guo, Robert S. Wallis, Piet H. van der Graaf, J. G. Coen van Hasselt
0citations -
Randomized placebo-controlled crossover study to assess tolerability and pharmacodynamics of zagociguat, a soluble guanylyl cyclase stimulator, in healthy elderly.
Sebastiaan J. W. van Kraaij, Laura G. J. M. Borghans, Erica Surya Klaassen, Pim Gal, Jeroen van der Grond, Ken Tripp, +3 more
0citations -
Proof of Pharmacology of Org 48775-0, a p38 MAP-kinase inhibitor, in Healthy Volunteers2020 preprint Biochemistry, Genetics and Molecular Biology Protein Kinase Regulation and GTPase Signaling Open access
Matthijs Moerland, Andrea J. Kales, Ulla N ssander, Pierre A. M. Peeters, Rob L. H. Nelissen, Jacobus Burggraaf
0citations -
SAFETY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF A CLC-1 INHIBITOR - A FIRST-IN-CLASS COMPOUND THAT ENHANCES MUSCLE EXCITABILITY: A PHASE I, SINGLE- AND MULTIPLE-ASCENDING DOSE STUDY2024 medRxiv preprint Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Titia Q. Ruijs, Catherine M.K.E. de Cuba, Jules A. A. C. Heuberger, Jane Bold, Thomas Groennebaek, Klaus Gjervig Jensen, +12 more
1citations -
Favourable pharmacokinetics of intradermal adalimumab over subcutaneous administration: results of a randomized controlled trial2020 preprint Pharmacology, Toxicology and Pharmaceutics Advancements in Transdermal Drug Delivery Open access
Justin Jacobse, Wouter ten Voorde, Anushka Tandon, Stefan G. Romeijn, Hendrika W. Grievink, Koen van der Maaden, +16 more
1citations -
Allele-specific collateral and fitness effects determine the dynamics of fluoroquinolone-resistance evolution2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Antibiotic Resistance in Bacteria Open access
Apostolos Liakopoulos, Linda B. S. Aulin, Matteo Buffoni, Efthymia Fragkiskou, J. G. Coen van Hasselt, Daniel E. Rozen
4citations
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