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A Multi-Omics Approach Reveals Enrichment in Metabolites Involved in the Regulation of the Glutathione Pathway in LIN28B-Dependent Cancer Cells2024 International Journal of Molecular Sciences article Medicine Neuroblastoma Research and Treatments Open access
Matteo Stocchero, Diana Corallo, Silvia Bresolin, Marcella Pantile, Paola Pirillo, Roberta Bortolozzi, +7 more
2citations -
Hyperpathway: visualizing organization of pathway-molecule enriched interactions in omics studies via hyperbolic bipartite network embedding2026 npj Systems Biology and Applications article Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Ilyes Abdelhamid, Ziheng Liao, Yuchi Liu, Armel Lefebvre, Aldo Acevedo, Carlo Vittorio Cannistraci
0citations -
Hyperpathway: visualizing organization of pathway-molecule enriched interactions in omics studies via hyperbolic bipartite network embedding2026 npj Systems Biology and Applications article Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Ilyes Abdelhamid, Ziheng Liao, Yuchi Liu, Armel Lefebvre, Carlo Vittorio Cannistraci
0citations -
Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data2020 Genome biology article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Christian H. Holland, Jovan Tanevski, Javier Perales-Patón, Jan G. Gleixner, Manu P. Kumar, Elisabetta Mereu, +6 more
367citations -
Discovering heart failure patient pathways through event enrichment and abstraction2026 International Journal of Medical Informatics article Business, Management and Accounting Business Process Modeling and Analysis Open access
Anton Antonov, Harry H. Beyel, Marlo Verket, Christopher T. Schwanen, Viki Peeva, Marco Pegoraro, +5 more
0citations -
Effects of enrichment strategies on outcome of adrecizumab treatment in septic shock: Post-hoc analyses of the phase II adrenomedullin and outcome in septic shock 2 trial2022 Frontiers in Medicine article Medicine Sepsis Diagnosis and Treatment Open access cited by 4 patents
Dirk P. T. van Lier, Adrien Picod, Gernot Marx, Pierre‐François Laterre, Oliver Hartmann, Claudia Knothe, +6 more
22citations -
OP0155 RA RISK GENES ARE DIFFERENTIALLY EXPRESSED BETWEEN (PEAC) PATHOTYPES IN SYNOVIUM WITH A CLEAR ENRICHMENT IN THE LYMPHOID-RICH PATHOTYPE2025 Annals of the Rheumatic Diseases conference-abstract Medicine Rheumatoid Arthritis Research and Therapies Open access
Inez C Den Hond, Marcel J. T. Reinders, Myles Lewis, Costantino Pitzalis, Rachel Knevel, Erik B. van den Akker
1citations -
PlantMetWiki: a FAIR knowledge graph for plant metabolic pathway cross-species representation and integration2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Elena Del Pup, M Muller, Marvin Martens, Egon Willighagen, Marnix H. Medema, Denise Slenter, +1 more
0citations -
German longevity study reveals novel rare pro-longevity alleles clustering in mTOR signaling pathway2025 GeroScience article Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Daniel Kolbe, Janina Dose, Pasquale C. Putter, Malte Ziemann, Matthias Laudes, P. Eline Slagboom, +3 more
4citations -
Neutrophil degranulation, NETosis and platelet degranulation pathway genes are co-induced in whole blood up to six months before tuberculosis diagnosis2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Tuberculosis Research and Epidemiology Open access
Stuart Meier, James A. Seddon, Elizna Maasdorp, Léanie Kleynhans, Nelita du Plessis, Andre Gareth Loxton, +13 more
3citations -
The Omega‐6 Lipid pathway shift is associated with neutrophil influx and structural lung damage in early cystic fibrosis lung disease2024 Clinical & Translational Immunology article Medicine Cystic Fibrosis Research Advances Open access
Lisa J. M. Slimmen, Jelle Y. Broos, B. Manaï, Silvia Estevão, Martin A. Giera, Gijs Kooij, +2 more
4citations -
Additional file 2 of Metabolomic predictors of phenotypic traits can replace and complement measured clinical variables in population-scale expression profiling studies2022 Figshare dataset Biochemistry, Genetics and Molecular Biology Metabolomics and Mass Spectrometry Studies Open access
Anna Niehues, Daniele Bizzarri, Marcel J. T. Reinders, P. Eline Slagboom, Alain J. van Gool, Erik B. van den Akker, +1 more
0citations -
A collaborative network analysis for the interpretation of transcriptomics data in Huntington’s disease2025 Scientific Reports article Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Ozan Özışık, Nazli Sila Kara, Tooba Abbassi‐Daloii, Morgane Térézol, Elsa C. Kuijper, Núria Queralt-Rosiñach, +7 more
1citations -
Collaborative network analysis for the interpretation of transcriptomics data in rare diseases, an application to Huntington’s disease2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Ozan Özışık, Tooba Abbassi‐Daloii, Morgane Térézol, Núria Queralt-Rosiñach, Annika Jacobsen, Osman Uğur Sezerman, +5 more
0citations