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Mechanobiological feedback loops and quantitative decision thresholds in organ fibrosis: Translational principles for antifibrotic therapy0citations
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Diet and exercise reduce pre-existing NASH and fibrosis and have additional beneficial effects on the vasculature, adipose tissue and skeletal muscle via organ-crosstalk
Anita M. van den Hoek, Jelle C. B. C. de Jong, Nicole Worms, Anita van Nieuwkoop, Marijke Voskuilen, Aswin L. Menke, +4 more
53citations -
Fibrosis: cross-organ biology and pathways to development of innovative drugs2025 Nature Reviews Drug Discovery review Medicine Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Open access
Florian Rieder, Laura E. Nagy, Toby M. Maher, Jörg H. W. Distler, Rafael Kramann, Boris Hinz, +1 more
100citations -
Biomedical applications of polysaccharide nanoparticles for chronic inflammatory disorders: Focus on rheumatoid arthritis, diabetes and organ fibrosis2021 Carbohydrate Polymers article Pharmacology, Toxicology and Pharmaceutics Advanced Drug Delivery Systems Open access
Prince Allawadhi, Vishakha Singh, Kannan Govindaraj, Isha Khurana, Lopmudra P. Sarode, Umashanker Navik, +4 more
89citations -
Publisher Correction: Fibrosis: cross-organ biology and pathways to development of innovative drugs2025 Nature Reviews Drug Discovery erratum Medicine Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Open access
Florian Rieder, Laura E. Nagy, Toby M. Maher, Jörg H. W. Distler, Rafael Kramann, Boris Hinz, +1 more
12citations -
New Aspects of Kidney Fibrosis–From Mechanisms of Injury to Modulation of Disease2022 Frontiers in Medicine article Medicine Chronic Kidney Disease and Diabetes Open access cited by 1 patent
Marcus Johannes Moeller, Rafael Kramann, Twan Lammers, Bernd Höppe, Eicke Latz, Isis Ludwig‐Portugall, +5 more
51citations -
Betaine alleviates doxorubicin‐induced nephrotoxicity by preventing oxidative insults, inflammation, and fibrosis through the modulation of Nrf2/HO−1/NLRP3 and TGF‐β expression2023 Journal of Biochemical and Molecular Toxicology article Medicine Chemotherapy-induced organ toxicity mitigation Open access
Poonam Yadav, Sumeet Kumar Singh, Sampat Singh Tanwar, Abhishek Sehrawat, Amit Khurana, Jasvinder Singh Bhatti, +1 more
30citations -
Fibrosis and Immune Cell Infiltration Are Separate Events Regulated by Cell-Specific Receptor Notch3 Expression2020 Journal of the American Society of Nephrology article Medicine Chronic Kidney Disease and Diabetes Open access
Sabine Brandt, Tobias Malte Ballhause, Delia Lidia Șalaru, Hien Minh Le-Deffge, Yan Fu, Lars Philipsen, +10 more
30citations -
End of preservation normothermic machine perfusion of porcine kidneys after ischaemic injury reprograms metabolism and induces fibrosis after transplant despite unchanged function: insights from the renal proteome2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Organ Transplantation Techniques and Outcomes Open access
John F. Mulvey, Corinna Snashall, Kaithlyn M. Rozenberg, Maria Letizia Lo Faro, Marco Eijken, Stine Lohmann, +10 more
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Oncofetal protein CRIPTO regulates wound healing and fibrogenesis in regenerating liver and is associated with the initial stages of cardiac fibrosis2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Liver physiology and pathology Open access
Sofia Karkampouna, Danny van der Helm, Bart van Hoek, Hein W. Verspaget, Marie‐José Goumans, Minneke J. Coenraad, +2 more
2citations