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Molecular basis of ligand binding and receptor activation at the human A3 adenosine receptor2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Adenosine and Purinergic Signaling Open access
Liudi Zhang, Jesse I. Mobbs, Felix M. Bennetts, Hariprasad Venugopal, Anh T. N. Nguyen, Arthur Christopoulos, +5 more
1citations -
Engineered chemotaxis core signaling units indicate a constrained kinase-off state2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Bacterial Genetics and Biotechnology Open access
Alise R. Muok, Teck Khiang Chua, Madhur Srivastava, Wen Jing Yang, Zachary A. Maschmann, Petr P. Borbat, +5 more
4citations -
Structural polymorphism of α-synuclein fibrils alters pathway of Hsc70 mediated disaggregation2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Parkinson's Disease Mechanisms and Treatments Open access
Jessica Tittelmeier, Thi Lieu Dang, Tracy Bellande, Virginie Redeker, Alexander Kai Buell, Ronald Melki, +3 more
4citations -
DNA polymerase actively and sequentially displaces single-stranded DNA-binding proteins2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Longfu Xu, Shikai Jin, Mia Urem, Seung‐Joo Lee, Meindert Hugo Lamers, Xun Chen, +2 more
0citations -
Impact of Phosphorylation on the Physiological Form of Human alpha-Synuclein in Aqueous Solution2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Parkinson's Disease Mechanisms and Treatments Open access
Emile De Bruyn, Anton Emil Dorn, Giulia Rossetti, Claudio O. Fernández, Tiago F. Outeiro, Jörg Bernhard Schulz, +1 more
2citations -
Diclofenac and other Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) are Competitive Antagonists of the human P2X3 Receptor2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Adenosine and Purinergic Signaling Open access
Laura Grohs, Linhan Cheng, Saskia Cönen, Bassam G. Haddad, Astrid S. Obrecht, Idil Toklucu, +6 more
0citations -
AlphaFold 3 captures oligomeric states and interaction dynamics of MLO ion channels2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Protein Structure and Dynamics Open access
Jan Hübbers, Chandan Kumar Das, Alexander Speck, Myriam Elisabeth Fuerst, Hanna Simon, Marie Laufens, +4 more
1citations -
Exploring Conformational Transitions of RNA Dimers via Machine Learning Potentials2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology RNA and protein synthesis mechanisms Open access
Leonardo Rafael Medrano Sandonas, Macarena Tolmos Nehme, Luis Fernando Cofas‐Vargas, Gustavo E. Olivos-Ramírez, Gianaurelio Cuniberti, Simón Poblete, +1 more
0citations -
A blueprint for high affinity SARS-CoV-2 Mpro inhibitors from activity-based compound library screening guided by analysis of protein dynamics2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Computer Science Computational Drug Discovery Methods Open access
Jonas Goßen, Simone Albani, Anton Hanke, Benjamin Philipp Joseph, Cathrine C. Bergh, Maria Kuzikov, +14 more
5citations -
Transport mechanism of DgoT, a bacterial homolog of SLC17 organic anion transporters2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Drug Transport and Resistance Mechanisms Open access
Nataliia Dmitrieva, Samira Gholami, Claudia Alleva, Paolo Carloni, Mercedes Alfonso‐Prieto, Christoph Fahlke
2citations -
Unraveling the Phase Behavior, Mechanical Stability, and Protein Reconstitution Properties of Polymer-Lipid Hybrid Vesicles2023 ChemRxiv preprint Biochemistry, Genetics and Molecular Biology Lipid Membrane Structure and Behavior Open access
Wagner Augusto Müller, Paul A. Beales, André Rodrigues Muniz, Lars J. C. Jeuken
0citations -
Rational evolution of a recombinant DNA polymerase for efficient incorporation of unnatural nucleotides by dual-site boosting2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization Open access
Ruyin Cao, Lili Zhai, Qingqing Xie, Zi Wang, Yue Zheng, Wenwei Zhang, +5 more
0citations -
Unraveling the Phase Behavior, Mechanical Stability, and Protein Reconstitution Properties of Polymer-Lipid Hybrid Vesicles2023 ChemRxiv preprint Biochemistry, Genetics and Molecular Biology Lipid Membrane Structure and Behavior Open access
Wagner Augusto Müller, Paul A. Beales, André Rodrigues Muniz, Lars J. C. Jeuken
0citations -
Water-triggered, irreversible conformational change of SARS-CoV-2 main protease on passing from the solid state to aqueous solution2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Protein Structure and Dynamics Open access
Narjes Ansari, Valerio Rizzi, Paolo Carloni, Michele Parrinello
4citations