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Stopping Versus Continuing Metformin in Patients With Advanced CKD: A Nationwide Scottish Target Trial Emulation Study2024 American Journal of Kidney Diseases article Medicine Diabetes Treatment and Management Open access
Emilie J. Lambourg, Edouard L. Fu, Stuart J. McGurnaghan, Bryan Ronald Conway, Neeraj Dhaun, Christopher Henry Grant, +13 more
7citations -
The influence of metformin treatment on the circulating proteome2025 EBioMedicine article Biochemistry, Genetics and Molecular Biology Metabolism, Diabetes, and Cancer Open access
Ben J. Connolly, LAURA J. MCCREIGHT, Roderick C. Slieker, Khaled Bedair, Louise A. Donnelly, Juliette A. de Klerk, +15 more
5citations -
Metformin alters mitochondria-related metabolism and enhances human oligodendrocyte function2025 Nature Communications article Neuroscience Neurogenesis and neuroplasticity mechanisms Open access
Nina-Lydia Kazakou, Nadine Bestard-Cuche, Laura J. Wagstaff, Kellie Horan, Luise A. Seeker, Sunniva M. K. Bøstrand, +7 more
18citations -
Quantitative Systems Pharmacology Modeling Framework of Autophagy in Tuberculosis: Application to Adjunctive Metformin Host-Directed Therapy2022 Antimicrobial Agents and Chemotherapy article Medicine Tuberculosis Research and Epidemiology Open access
Krina Mehta, Tingjie Guo, Robert S. Wallis, Piet H. van der Graaf, J. G. Coen van Hasselt
5citations -
Study protocol of a randomized, double-blind, placebo-controlled, multi-center trial to treat antipsychotic-induced weight gain: the Metformin-Lifestyle in antipsychotic users (MELIA) trial
Nini de Boer, Sinan Gülöksüz, Caroline G. C. M. van Baal, Leonie Willebrands, Jeroen Deenik, Christiaan H. Vinkers, +18 more
5citations -
Effects of Hydrochlorothiazide and Metformin on Aquaresis and Nephroprotection by a Vasopressin V2 Receptor Antagonist in ADPKD2022 Clinical Journal of the American Society of Nephrology article Biochemistry, Genetics and Molecular Biology Genetic and Kidney Cyst Diseases Open access
Bart J. Kramers, Iris W. Koorevaar, Maatje D.A. van Gastel, Harry van Goor, Kenneth R. Hallows, Hiddo J.L. Heerspink, +7 more
36citations -
Increased Post-Hypoxic Oxidative Stress and Activation of the PERK Branch of the UPR in Trap1-Deficient Drosophila melanogaster Is Abrogated by Metformin2021 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Endoplasmic Reticulum Stress and Disease Open access
Alma Kokott-Vuong, Jennifer Jung, Aaron T. Fehr, Nele Kirschfink, Rozina Noristani, Aaron Voigt, +4 more
17citations -
Metformin as adjunctive therapy in combination with multidrug treatment for multibacillary leprosy: A protocol for a randomized double-blind, controlled Phase 2 trial in Indonesia (MetLep Trial)
Hana Krismawati, Sri Vitayani Muchtar, Mutia Rahardjani, Nindya N Utami, Margareta Oktaviani, Khairunnisa Puspatriani, +14 more
5citations -
A Phase Ib Clinical Trial of Metformin and Chloroquine in Patients with IDH1-Mutated Solid Tumors2021 Cancers article Biochemistry, Genetics and Molecular Biology Metabolism, Diabetes, and Cancer Open access
Mohammed Khurshed, Remco Jurriaan Molenaar, Myra Ellen Van Linde, Ron A. A. Mathôt, Eduard A. Struys, Tom van Wezel, +4 more
30citations -
Effects of Hydrochlorothiazide and Metformin on Aquaresis and Nephroprotection by a Vasopressin V2 Receptor Antagonist in ADPKD: A Randomized Crossover Trial.2022 PubMed article Biochemistry, Genetics and Molecular Biology Genetic and Kidney Cyst Diseases Open access
Bart J. Kramers, Iris W. Koorevaar, Maatje D.A. van Gastel, Harry van Goor, Kenneth R. Hallows, Hiddo J.L. Heerspink, +6 more
24citations -
Metformin and statin use associate with plasma protein N-glycosylation in people with type 2 diabetes2020 BMJ Open Diabetes Research & Care article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access cited by 1 patent
Sunny S Singh, Annemieke Naber, Viktoria Dotz, Emma Schoep, Elham Memarian, Roderick C. Slieker, +8 more
15citations -
Enhanced fatty acid oxidation through Metformin and Baicalin as therapy for COVID-19 and associated inflammatory states in lung and kidney2023 Free Radical Biology and Medicine article Biochemistry, Genetics and Molecular Biology Metabolism, Diabetes, and Cancer Open access
Verónica Miguel, Jessica Tituaña, Belén Sirera, J. Ignacio Herrero, Irene Ranz, Laura Fernández, +9 more
1citations -
Données récentes sur le mécanisme d'action de la metformine dans le diabète de type 2 Recent advances on elucidating the mechanism of metformin action in type 2 diabetes0citations
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Sociodemographic and biological determinants of insulin initiation in type 2 diabetes: a cohort study using routinely collected primary care data2025 British Journal of General Practice article Medicine Diabetes Treatment and Management Open access
Sukainah Alfaraj, Rimke Cathelijne Vos, Marco René Spruit, Rolf H. H. Groenwold, Dennis Owen Mook-Kanamori
0citations