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MMR vaccination induces a trained immunity program characterized by functional and metabolic reprogramming of γδ T cells2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Immune responses and vaccinations
Rutger Jan Röring, Priya A. Debisarun, Javier Botey-Bataller, Tsz Kin Suen, Ozlem Pinar Bulut, Gizem Kılıç, +19 more
4citations -
Mixed-Integer Optimization for Loopless Flux Distributions in Metabolic Networks2024 arXiv (Cornell University) preprint Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
João Dionísio, Tim Donkiewicz, Leon Eifler, Ambros Gleixner, Katrin Halbig, Ivo Hedtke, +9 more
89citations -
TCA cycle rewiring underpins implantation and histone acetylation programming2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Eleni Kafkia, David Pladevall‐Morera, Lidia Argemi‐Muntadas, Gangqi Wang, Roberta Noberini, Sandra Bagés‐Arnal, +6 more
2citations -
Metabolic Syndrome Parameters, Determinants, and Biomarkers in Adult Survivors of Childhood Cancer: Protocol for the Dutch Childhood Cancer Survivor Study on Metabolic Syndrome (Dutch LATER METS) (Preprint)
Vincent G. Pluimakers, Marta F. Fiocco, Jenneke E. van Atteveld, Monique G. G. Hobbelink, Dorine Bresters, Eline van Dulmen‐den Broeder, +12 more
0citations -
XomicsToModel: Omics data integration and generation of thermodynamically consistent metabolic models2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
German Preciat, Agnieszka B. Wegrzyn, Ines Thiele, Thomas Hankemeier, Ronan M. T. Fleming
10citations -
O-GlcNAcylation drives macrophage IL-4 responsiveness and tissue residency through metabolic and cell cycle calibration2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Graham A. Heieis, Conor M. Finlay, Thiago A. Patente, Martina Erbì, Thijs van der Meer, Jordan O'Keeffe, +7 more
3citations -
Integration of a fasting-mimicking diet program in primary care for type 2 diabetes reduces the need for medication – a 12-month randomised controlled trial
Elske L. van den Burg, Marjolein P. Schoonakker, Petra G. van Peet, M. Elske van den Akker‐van Marle, Hildo J. Lamb, Valter Daniel Longo, +2 more
4citations -
Spatiotemporal heterogeneity of glioblastoma is dictated by microenvironmental interference2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Glioma Diagnosis and Treatment Open access
Vidhya Madapusi Ravi, Paulina Will, Jan Kueckelhaus, Na Sun, Kevin Joseph, Henrike Salié, +20 more
12citations -
A Novel FNDC1-NAMPT-NAD axis is Implicated in Small and Large-vessel Arterial Disease and Drives Vascular Calcification2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Parathyroid Disorders and Treatments Open access
Sujin Lee, Yugene Y. Guo, Lova Prasadareddy Kajuluri, Kangsan Roh, Kuldeep Singh, Wanlin Jiang, +28 more
0citations -
Adaptive laboratory evolution rewires Pseudomonas putida for resource-efficient acetate assimilation2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Nicolás Gurdo, Aparajitha Srinivasan, Tommaso Tagliani, Melanie Filbig, Nicolas T. Wirth, Josefin Johnsen, +13 more
0citations -
Same-section spatial metabolo-transcriptomics using Stereo-meta-seq reveals DHA-driven kidney maturation2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Roan H van Scheppingen, Baihua Wu, Yumeng Zhang, Sytske Schep, Ulli Winter, Yilong Zou, +9 more
0citations -
Polyploid cardiomyocytes define disease-specific transcriptional states in the mammalian heart2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Congenital heart defects research Open access
Paul Kießling, Mehdi Joodaki, Daryna Pikulska, Emilia Scheidereit, Giulia Cesaro, Mayra Ruiz, +52 more
5citations -
O-GlcNAcylation and low glycolysis underpin Th2 polarization by dendritic cells2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Leonard R. Pelgrom, Marjolein Quik, Thiago A. Patente, Graham A. Heieis, Alexey Sergushichev, Jie Kang, +18 more
0citations -
Zero-Shot Metabolite Prediction from Gene Expression via Physics-Informed Graph Neural Networks2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Claudio Novella-Rausell, Ton J. Rabelink, Ahmed Essam Mahfouz
0citations -
FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Liver Disease Diagnosis and Treatment Open access
Cong Liu, Milena Schönke, Borah Spoorenberg, Joost M. Lambooij, Hendrik J.P. van der Zande, Enchen Zhou, +12 more
8citations -
Disentangling the genetic basis of rhizosphere microbiome assembly in tomato2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Agricultural and Biological Sciences Plant-Microbe Interactions and Immunity Open access
Ben O. Oyserman, Stalin Sarango Flores, Thom Griffioen, Xinya Pan, Elmar van der Wijk, Lotte J. U. Pronk, +10 more
7citations -
The immediate cellular response to whole-genome doubling is conserved across polyploid contexts2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Agricultural and Biological Sciences Chromosomal and Genetic Variations Open access
Cindy C. Geerlings, Gabriella Darmasaputra, Christa Jordan Ortiz, Susana M. Chuva de Sousa Lopes, Hans C. Clevers, Matilde Galli
0citations -
Distinct colorectal cancer genotypes shape microbial ecosystems and reveal stage-specific microbiota dependencies2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Valentina Brunner, Nicholas Bodenstein, Antonio Enrico Zaurito, M Silva, Frederic Saab, Fabian Springer, +18 more
0citations -
The VarA-CsrA regulatory pathway influences cell shape in Vibrio cholerae2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Bacterial Genetics and Biotechnology Open access
Leonardo F. Lemos Rocha, Katharina Peters, Jamie S. Depelteau, Ariane Briegel, Waldemar Vollmer, Melanie Blokesch
0citations -
Impaired community assembly after depletion of key rhizosphere microorganisms compromises plant health2022 Research Square preprint Agricultural and Biological Sciences Plant-Microbe Interactions and Immunity Open access
Yanyan Zhou, Zhen Yang, Jinguang Liu, Xingxiang Wang, Chuan‐Chao Dai, Víctor J. Carrión, +1 more
0citations