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Proinflammatory phenotype of iPS cell-derived JAK2 V617F megakaryocytes induces fibrosis in 3D in vitro bone marrow niche2024 Stem Cell Reports article Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Niclas Flosdorf, Janik Böhnke, Marcelo A. S. Toledo, Niklas Lutterbach, Vanesa Gómez Lerma, Martin Graßhoff, +18 more
18citations -
CALR frameshift mutations in MPN patient-derived iPSCs accelerate maturation of megakaryocytes2021 Stem Cell Reports article Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Kathrin Olschok, Lijuan Han, Marcelo A. S. Toledo, Janik Böhnke, Martin Graßhoff, Ivan G. Costa, +14 more
25citations -
CALR frameshift mutations in MPN patient-derived iPS cells accelerate maturation of megakaryocytes2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Kathrin Olschok, Lijuan Han, Marcelo A. S. Toledo, Janik Böhnke, Martin Graßhoff, Ivan G. Costa, +14 more
0citations -
Melatonin nanoparticles inhibit mutant hematopoiesis & restore bone marrow architecture in myeloproliferative neoplasms2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Circadian rhythm and melatonin Open access
Siddharth Gupta, Alessandro Motta, Sara Elsafy, Shiva Khorshid, Alessia Nucci, Vishrutha Sampath, +21 more
0citations -
Spatial profiling of the spleen in mouse and human myelofibrosis reveals complement-driven immune-stromal interactions as a therapeutic target2026 Cell stem cell article Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Bérénice Dugué, Pia Wanner, Mayra L. Ruiz Tejada Segura, Mohamed Saad, Lucas Greven, Katrin Götz, +33 more
2citations -
NicheSphere reveals Spp1⁺ macrophages as central hubs coordinating fibrotic remodeling in myeloproliferative neoplasms2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Hélène F.E. Gleitz, Mayra L. Ruiz Tejada Segura, James Shiniti Nagai, Stijn N. R. Fuchs, Gerjanne Vroeg in de Wei, Inge Snoeren, +16 more
1citations -
PDE3A-SLFN12 Molecular Glues Target Multiple KIT D816V Cell Types in Preclinical Models of Mast Cell Malignancies2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Phosphodiesterase function and regulation Open access
Xuhuang Fu, Anne Kaiser, Payal Chawla, Axel Choidas, Peter Habenberger, Tiago Maié, +17 more
0citations -
Cell-Specific Role of Platelet-Derived Growth Factor Subunit B (PDGF-B) in Kidney Fibrosis2024 Journal of the American Society of Nephrology article Medicine Systemic Sclerosis and Related Diseases
Barbara M. Klinkhammer, Eva Miriam Buhl, Tim Caspers, Dickson W.L. Wong, Michaël Goedertier, David Laurin Hölscher, +2 more
0citations -
2003 – PHYSICALLY INTERACTING CELL SEQUENCING IN BONE MARROW FIBROSIS REVEALS DISTINCT CELLULAR NICHES IN FIBROSIS2024 Experimental Hematology article Biochemistry, Genetics and Molecular Biology Cancer Genomics and Diagnostics Open access
Hélène F.E. Gleitz, James Shiniti Nagai, Mayra Ruiz, Stijn N. R. Fuchs, Inge Snoeren, Aurélie Boeree, +4 more
0citations -
Plasmacytoid dendritic cells regulate megakaryocyte and platelet homeostasis2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Platelet Disorders and Treatments Open access
Florian Christoph Gaertner, Hellen Cristina Ishikawa-Ankerhold, Susanne Stutte, Jutta Weitz, Anne Dueck, Zhe Zhang, +22 more
2citations