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Non-apoptotic FAS signaling controls mTOR activation and extrafollicular maturation in human B cells2024 Science Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Julian Staniek, Geoffroy Andrieux, Melanie Boerries, Iga Janowska, Manuel Fuentes, Paula Díez, +37 more
25citations -
Leucine Reconstitutes Phagocytosis-Induced Cell Death in E. coli-Infected Neonatal Monocytes—Effects on Energy Metabolism and mTOR Signaling2021 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Cell death mechanisms and regulation Open access
Stephan Dreschers, Kim Ohl, Julia Möllmann, Klaus Tenbrock, Thorsten W Orlikowsky
5citations -
2,8-Dihydroxyadenine-induced nephropathy causes hexosylceramide accumulation with increased mTOR signaling, reduced levels of protective SirT3 expression and impaired renal mitochondrial function2023 Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease article Medicine Chronic Kidney Disease and Diabetes Open access
Julia Moellmann, Katja Krueger, Dickson W.L. Wong, Barbara M. Klinkhammer, Eva Miriam Buhl, Jonas Dehairs, +7 more
19citations -
Personalized Medicine Approach in a DCM Patient with LMNA Mutation Reveals Dysregulation of mTOR Signaling2022 Journal of Personalized Medicine article Medicine Cardiomyopathy and Myosin Studies Open access
Balram Neupane, Kabita Pradhan, Audrey Ortega-Ramírez, Parwez Aidery, Vytautas Kučikas, Matthias Marks, +6 more
11citations -
German longevity study reveals novel rare pro-longevity alleles clustering in mTOR signaling pathway2025 GeroScience article Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Daniel Kolbe, Janina Dose, Pasquale C. Putter, Malte Ziemann, Matthias Laudes, P. Eline Slagboom, +3 more
4citations -
The sodium‐glucose co‐transporter‐2 inhibitor ertugliflozin modifies the signature of cardiac substrate metabolism and reduces cardiac mTOR signalling, endoplasmic reticulum stress and apoptosis
Julia Moellmann, Pascal A. Mann, Ben Arpad Kappel, Florian Kahles, Barbara M. Klinkhammer, Peter Boor, +5 more
52citations -
Models of KPTN-related disorder implicate mTOR signalling in cognitive and overgrowth phenotypes2023 Brain article Biochemistry, Genetics and Molecular Biology Genetics and Neurodevelopmental Disorders Open access
Maria O. Levitin, Lettie E. Rawlins, Gabriela Sánchez-Andrade, Osama A. Arshad, Stephan C. Collins, Stephen J. Sawiak, +35 more
12citations -
Multi-omics analyses of cancer-linked clinical salmonellae reveal bacterial-induced host metabolic shift and mTOR-dependent cell transformation2024 Cell Reports article Agricultural and Biological Sciences Salmonella and Campylobacter epidemiology Open access
Virginie Stévenin, Claudia E. Coipan, Janneke W. Duijster, Daphne M. van Elsland, Linda Voogd, Lise Bigey, +8 more
5citations -
Simultaneous targeting of AMPK and mTOR is a novel therapeutic strategy against prostate cancer2024 Cancer Letters article Biochemistry, Genetics and Molecular Biology PI3K/AKT/mTOR signaling in cancer Open access
Gangyin Zhao, Gabriel Forn‐Cuní, Marvin Scheers, Pier Pieterszoon Lindenbergh, Jie Yin, Quint C. van Loosen, +3 more
22citations -
mTORC1 signaling in antigen-presenting cells of the skin restrains CD8+ T cell priming2022 Cell Reports article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Leonard R. Pelgrom, Thiago A. Patente, Frank Otto, Lonneke V. Nouwen, Arifa Ozir‐Fazalalikhan, Alwin J. van der Ham, +4 more
8citations -
Deletion of mTOR in liver epithelial cells enhances hepatic metastasis of colon cancer2021 The Journal of Pathology article Biochemistry, Genetics and Molecular Biology PI3K/AKT/mTOR signaling in cancer Open access
Long R. Jiao, Roman Eickhoff, Sandra Jumpertz, Merve Erdem, Andreas Kroh, Hans Duimel, +7 more
7citations -
Hepatocellular loss of mTOR aggravates tumor burden in nonalcoholic steatohepatitis-related HCC2023 Neoplasia article Biochemistry, Genetics and Molecular Biology PI3K/AKT/mTOR signaling in cancer Open access
Andreas Kroh, Jeanette Walter, Athanassios Fragoulis, Diana Möckel, Twan Lammers, Fabian M. Kiessling, +10 more
8citations -
MYC is a clinically significant driver of mTOR inhibitor resistance in breast cancer2023 The Journal of Experimental Medicine article Biochemistry, Genetics and Molecular Biology PI3K/AKT/mTOR signaling in cancer Open access
Jinhyuk Bhin, Julia Yemelyanenko, Xue Chao, Sjoerd Klarenbeek, Mark Opdam, Yuval Malka, +18 more
26citations -
CD27 costimulation supports metabolic fitness of CD4+ T cells by enhancing de novo nucleotide and protein synthesis2025 The Journal of Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Thi Tran Ngoc Minh, Lotte J. Verleng, Ellen Schrama, Julia Busselaar, Mo D. Staal, Evert de Vries, +5 more
6citations -
The interplay between tauopathy and aging through interruption of UPR/Nrf2/autophagy crosstalk in the Alzheimer’s disease transgenic experimental models2023 International Journal of Neuroscience article Medicine Alzheimer's disease research and treatments
Javad Amini, Naser Sanchooli, Mohammad-Hossein Milajerdi, Maryam Baeeri, Mohammad Haddadi, Nima Sanadgol
19citations -
Plexin C1 modulates metabolic programming for resolution of severe inflammation2025 Cell Communication and Signaling article Immunology and Microbiology Phagocytosis and Immune Regulation Open access
Andreas Körner, Michael Koeppen, Jasvir Kaur, Julia Catherine Fitzgerald, Sarantos Kostidis, Torsten Kaussen, +5 more
1citations -
Comparative genomic profiling of glandular bladder tumours2020 Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin article Medicine Urinary and Genital Oncology Studies Open access
Angela Maurer, Nadina Ortiz-Bruechle, Karolína Guricová, Michael Rose, Ronja Morsch, Stefan Garczyk, +12 more
44citations