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A small molecule screen identifies novel inducers of EMT that may increase epicardium-driven repair of the heart2020 European Heart Journal article Biochemistry, Genetics and Molecular Biology Congenital heart defects research
Esther Dronkers, Tessa van Herwaarden, Marie‐José Goumans, Anke M. Smits
1citations -
Identifying Novel Inhibitors for Hepatic Organic Anion Transporting Polypeptides by Machine Learning-Based Virtual Screening2022 Journal of Chemical Information and Modeling article Computer Science Computational Drug Discovery Methods Open access
Alzbeta Tuerkova, Brandon J. Bongers, Ulf Norinder, Orsolya Ungvári, Virág Székely, Andrey Tarnovskiy, +4 more
24citations -
Automated Parallel Synthesis Accelerates Virtual Screening Hit Discovery2026 Journal of the American Chemical Society article Biochemistry, Genetics and Molecular Biology Chemical Synthesis and Analysis Open access
Sean M. McKenna, Martin Šícho, Cas van der Horst, Jesse Maasland, Edith van der Nol, Gianluca Turco, +4 more
0citations -
Engineering and application of a biosensor with focused ligand specificity2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Dennis Della Corte, Hugo L. van Beek, Falk Syberg, Marcus Schallmey, Felix Tobola, Kai U. Cormann, +9 more
110citations -
Novel assays monitoring direct glucocorticoid receptor protein activity exhibit high predictive power for ligand activity on endogenous gene targets2022 Biomedicine & Pharmacotherapy article Biochemistry, Genetics and Molecular Biology Estrogen and related hormone effects Open access
Laura Van Moortel, Jonathan Thommis, Brecht Maertens, Dorien Clarisse, Delphine De Sutter, Claude Libert, +4 more
20citations -
Multicentric Analytical and Inter-observer Comparability of Four Clinically Developed Programmed Death-ligand 1 Immunohistochemistry Assays in Advanced Clear-cell Renal Cell Carcinoma
Ulrich J. Sommer, Markus Eckstein, Johannes U Ammann, Till A. Braunschweig, Stephan Macher-Göppinger, Kristina Schwamborn, +10 more
13citations -
High-throughput competitive binding assay for targeting RNA tertiary structures with small molecules: application to pseudoknots and G-quadruplexes2025 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology RNA and protein synthesis mechanisms Open access
Sophie E.L. Wintermans, Jana S Hoffmann, Victor van Kuijk, Yelda Durmus, Mariska D. Tacoma, Indy Broekhuizen, +6 more
1citations -
High throughput identification of human monoclonal antibodies and heavy-chain-only antibodies to treat snakebite2024 Toxicon X article Biochemistry, Genetics and Molecular Biology Venomous Animal Envenomation and Studies Open access
Julien Slagboom, Wietse M. Schouten, Rien van HAPEREN, Mieke Veltman, Mátyás A. Bittenbinder, Freek J. Vonk, +4 more
7citations -
Combining AlphaFold with Focused Virtual Library Design in the Development of Novel CCR2 and CCR5 Antagonists2025 Journal of Chemical Information and Modeling article Computer Science Computational Drug Discovery Methods Open access
Khaled Essa, Kian Noorman van der Dussen, Yao Yao, Bente T.M. Bleijs, Natalia V. Ortiz Zacarı́as, Laura H. Heitman, +4 more
1citations -
Structure-Based Discovery of Mouse Trace Amine-Associated Receptor 5 Antagonists2023 Journal of Chemical Information and Modeling article Computer Science Computational Drug Discovery Methods Open access
Alessandro Nicoli, Verena Weber, Carlotta Bon, Alexandra Steuer, Stefano Gustincich, Raul R. Gainetdinov, +3 more
7citations -
Directed evolution of VanR biosensor specificity in yeast2020 Biotechnology Notes article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Vasil D’Ambrosio, Subrata Pramanik, Kati Goroncy, Tadas Jakočiūnas, David Schönauer, Mehdi D. Davari, +3 more
29citations -
Low Molecular Weight Inhibitors Targeting the RNA-Binding Protein HuR2023 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Benjamin Philipp Joseph, Verena Weber, Lisa Knüpfer, Alejandro Giorgetti, Mercedes Alfonso‐Prieto, Sybille Krauß, +2 more
10citations